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SARS2wEverything.aln
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SARS2wEverything.aln
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>Wencheng
----------MKLIILFLVLPCVEC--------------------------VE-----YI
KC---------S---TTQLGFLDLEKITYSLFDL--------------------------
--GDVGV-----------------------------------------------------
----------------------------------------NSTTLING----YFPSKDI-
-----------------------------------------------------NNW---L
CEKTG----------------------VSELYYGQAFYTILNKEGSAS------------
-----------------------------LKFL-------------------IQPIVYS-
------------------------------NS--SY-----VVFMV-----------YKS
GVL--------------------------DFSICYRNYF------QFAWN--IDPPP---
----------------------------PISCAFNR------------------------
------------RIYFG----------------DRHIYLGVIWRHGYVKIIT----PNFV
QQFELDNMHLEVIRVATGRYGSTS-----------SYVIVMPFQIVDKRSIFLVNYNQSG
YVSNLLNCSES-IEAQLKCKSRSFELQSGVYELAL-----EERVGGYYTVVTNVTGDC--
-----------N------NIKYLFSNFT-----------GNKQPLYAGNFASMSC-----
------------IVPFNFSINNGLLNNNSQLRGPNGEFKPFI--------DCKGINPIGL
F----------GSNGTCY---------SGM-----------KWRYWTRRFSGYNMSIEGV
AESFYDGGIGENECY----G-LLK------------------------------------
-------------------------GGQ----------------YN--------------
------DLWRFT-----------EVLYYKVR----------------FMEKG--------
-------------------------------------------------LDVCYGNLP--
---------------------PAPQVNKCNVWTFNDITFEGVLLE-TN----KTFNPQLK
ALYK---G--SMVVMIRIF-GIVYEVVPCIKTRLSVIY--NANNKNYSTLYRVANCNQID
TK-RSV-----HPV----------GLL----SRDGINTP----CGCLRNAMFSPNITVDS
Y--S--CKTLL----SDGYCVVF-------------------NNGSTEVVPIGIVGANTT
YNMPI-LEESFVELALDHVLVSESEYFQTEMPVFDIDCEKYICDNSESCRMLLEQYAGFC
SKITSDVKGN-SQLLNANTLAMYKNIV--PSGSIK---PIENF-----------G---D-
-FN-----------------MSM-FIDK------SG---------------RSV--LEDL
LFDKIVTTGPGFY-DDYYKC---RTT-------TVKDLVCAQYYNGIMVIPPIQDAETIG
MYGGIVAAGMTMGLFG---GQ---ATMGTWQTAMSARLNAVGVTQGMIMEDVQKLANGFN
TLATSV--------------SKMASVTADALSRIQGVVNANALQVELLARATMDNFGAIS
SNFEIIEKRLKQVQAEQQMDRVINGKMNALLNFVSNYKLKVSELTSIQQLVKQKVQECVH
AQSLRNGFCGS-GLHVMSIPQLVPNGVMFLHFSLVKNNSIIVKQTPGLCKED---K----
-------INCIV----PKSGI----------FVSKND--------SN-----WYITPRNK
YVPKNITNSDIIFTTYSE-NFTVINNTIQFPGI--EF--PQDGDFDGQIKNV---TLELQ
SLK---DVVANMSYLDLSNHTA--------------LLKNISEEVKKMNITVSQFKQYVK
YVKWPWYVWLLIVMALIAFGLVCFWIFMCTGCC-GLCDC--IRRSCRDSNTYEP------
--------------IEKIHIQ----
>SorexT14
----------MLILVFLSLVTVSLQ-----------------------------------
------------------------------------------------------------
--NVVVPFDN----YCNLD-------------------------ARYH------------
----------------------------------------NITVQSEK----PFNFNAT-
-----------------------------FYTTNQTC-----FDVNCTSSNTSNTF----
-------------------------------NSSDTITYSNCSSVTFN------GCVVKQ
FCVTQPCHCYYQTQQ----VSGFVFDGLSHTFV--------------PEISNYHVADVV-
------------------------------NK--TL-----T---------------RTT
NLC--------------------------SSVNVTIDYKQFLMLSSVEIN--STFVVTQF
VPSYVYNQDNFT----------------IKGDNFWVVANTTTVFVLQPKTPSNETLSLY-
-IKITNSSG-SLFVNVTICNYFRVLNNTDNTNTSSLVYTNCVFEKVAGGLQVVTLGVIWR
K--NVVTLHWLAQEVVTIELPFDPQWYGGDPALNGLYCNGWYANSLESPHTYLLKTNASG
HIVNSLWCNPDDELSSLQCAYKTFNLNRGVYSRTVHQK--VVYLQRF-SSTPKCVTN---
-----------KVNA--------DLVVR-------------GGFYATLTNCDYDLHGLLN
ISLLPQRWGGVNYTIP--PVVVPWVLKNP--DGTSRLWQ-----------QCVGVDVASA
N-------------TQCF---------KSI----------------SVSFVT--------
-----NA-----YLL----E-LLP------------------------------------
-------------------------GQC----------------V---------------
------SYYGYF--------TTGAAGLVAKN------------AIVGTFDLS--------
----------------------------------------------SGDTQTCMYQ----
-QQNTT---------------FEIPQNVCVSFTFDSQTIKGILTQ-FN----TTYP--SN
YTNILKHN--GVVKYVRID-GVSYVVKPC--------------------LFESVVKIVNN
ATYNHT------------------IISTSLCGENGTNTT----IGCIQTGFVNETLN---
---T--CDYSL----GNGFCANV---------------NKSMDVYKFIPSK-----QTND
YVVPI-SGMYNITLPTSYEPFTSTAYYQTRLEKLQVDCQHFVCDSNIHCLTLLQKYGDIC
TKITGDVNTVMASLTSLELDALQTVAL--EGLNVD-------Y-----------G---S-
-FN-----------------FSG-LMPQ-----RGT---------------RSF--IEDL
LFDKIVTTGPQFY-KDYYDC----HK---DK--TINDLLCAQQYNGMLVVPPIMDDATIA
MYGTIAGASVSAGMFG---GQ---AGMITWNTAVSARLNALGITQEVMQSDIQKIANAVN
GIVDHV--------------SNLAKTVAGGFEVIQAVVNQNGAQMMALVDGLQENFGAIS
NNFETINNRLNKLEADQQMDRLINGRLNVLQSFMTNYKIKVSAMQATQHTVNSIIKECVY
AQSTRNGFCGD-GKHIMSFMQNAPDGIFFIHFTMKPVQYINVTTTPGLCINN---T----
---------GIA----PKDGI----------FVFVNG--------------TWMVSPRNI
YNPRNVSNSDIVHYISCEANYTLVNNTIGSVVL-PQL-PNIGDDFNNLYENT---SKALE
EIK---NIYFNFTNLNLTTEIE--------------RLNSIAEEVKKLNITLSELGRYER
YVKWPWYVWLAIAVVMIVLVFILGCLLFMTGCC-GCCGC--CGGCCGKACSKPP------
-DY---------EELEKLHVA----
>AlphaCorona2012
----------MKLLTVLTLLACIRL---------------------------------VC
GCTDVNFDLFKT---ILS------------------------------------------
--TNRGS-----------------------------------------------------
--------------------------------I-------NGTAVISG----AYPSTNI-
-----------------------------------------------------SEW----
--------------------------------FCSGTVGRPSGIAKGI------------
--------------GIFAQTANVDYG-----------------SGGGGYTFSVSPSHST-
------------------------------NL--TW-----ELWVHRAW--------GAN
KPV--------------------------TIRLC--KWF-------QALP--FNQTSHQQ
----------------------------DAGPTNAIECLVNGS-----------------
-FPSHSALN-YMFGVTW----------------YEGLVRVIFPPTVFEMQLD---GLQW-
---------------EIVRFTGPI-----SGGKMTRFNVIK------DISSILVSTDAHG
AVDNFVYCDSG-FVSALQCKLRRFSLPPGVYSNTEVEY--PSALYTVVSNMTSCPERP--
-----------STSCTSSYCPLKRAVFS--NC----IVNYTSWVYDSSVKSNFQHL----
------------------ILPNGLFNPFI---------------------ECNGLNKIVT
N--------------SCV---------PGF-------------VLRVGRGKA--------
----LNK-----TVT------VPYLKT---------------------------------
-------------------------SEC--------------------------------
------FGWAWN--------DPQDSIFDW--------------WIADFVSSG--------
-------------------------------------------------AYVCTSN-P--
---------------------VAPRTGVCMTYTVEKTTFQGVLYE-SN----FTFSQYYN
LLY---AG--SQLKYVRIL-GIVYEVAACFEASYDVLF---ASNSSYGLLYRSFDCNQIH
IN-AER-----FRS----------RLLP---QHNGTATA----LGCLFNATYAPNDTFV-
---N--CSNPL----GDGFCADL--------------------KGTVAVRRMGFEAHDTT
YVANV-ISERYISLAIDQQLVLTEQFLQTTMPKFSVNCETYICDVSKACKNLLFRYGGFC
QKIEADIRGA-GVLLDSDISELYSTIVAKSSSLVP---QTDRF-----------N-----
--------------------VSQFFLPKNTAPSPPS-----------PYSSRSA--IEDI
LFSKIETTGPGFY-GDYYNC---KKN-------AIQDLTCAQYHNGILVIPPIMDAETMG
MYGGIAAGAVSLGIFG---GQ---AAIATWNTAIAGRLNALGVVQNALVDDVNKLANGFN
QLTSQV--------------GKLALSTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS
TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVY
AQSLRNGFCGQ-GLHVLSLMQNAPSGIMFFHYSLIPNNTITVKTTPGLCESDEIGA----
--------KCIV----AKNGI----------FV--SA-----------NLSYWQWSPRNI
YKPENLTFTNVIAVSR-GANYTTLNRTFDIPELNQSF--PIDEEFREYFQNM---SSELQ
ALK---NLTADMSKLNISEEIK--------------LINEIAHNVSMMHVEVEKFQKYVN
YVKWAWWQWLLIFIALTLLAGLMVWCCLATGCC-GMCGC--LAATCASCCDCKG---TKL
QSY----------EIEKIHIQ----
>RhinoHKU2
----------MKLFIVFVLLFRVCY-----------------------------------
CCDYVDFRLFNG---IFS------------------------------------------
--TSRGL-----------------------------------------------------
--------------------------------S-------NTTTVITG----AYPSTNK-
-----------------------------------------------------AKWFCPT
NVGR---------------------------PVGTGVGIGVYAQTAQA------------
-----------SYETGGSGAGGYTFS--------------------------VSPKHVT-
------------------------------NL--TW-----SLWVHRPW--------GAN
ANV--------------------------TVRLC--RWW-----QKFSFN--ETAHFQ--
----------------------------PAGPSSAFECLVNGS-----------------
-FPSSQHKG-YMFGVTW----------------YNDFVRIIFPPTVFELQLD---GLQW-
---------------EYVQFTGPV-----NAGRMTKFNVVT------EISSVLVLTDQSG
AVTRYSYCADG-FVNGLQCKLRLFDIPPGVYSNSEVEY--PVALYTVVHNMSVCPQRP--
-----------ESYCGSNYCPFKRVVFS--NC----VVNYTSWTSGLLRDYQHL------
------------------VLPNGKFNPFT---------------------ECNGLNRIVD
---------------DCV---------TGF-------------VLRVGRGTA--------
----VNR-----TVI------TPYLKP---------------------------------
-------------------------NEC--------------------------------
------FGWSWN--------DYQDSIYDW--------------WIADFVSTG--------
-------------------------------------------------AFVCEKN-P--
---------------------DAPRTGVCITYTIEKVTFQGVLYE-SN----FTFAQYYN
VLYF---G--SQLKYVRIL-GKVYEVAPCFEASYDVLF---RSSSSFGLLYRSFDCNQLR
IS-ASR-----FAE----------RLLP---SHNGTATA----LGCLFNATYAPNDTMV-
---N--CTNPL----GDGFCADL--------------------LSNVVVRRMTFEKHDTT
YVAPV-TNERFTELPLDHQLVLTEQFLQTTMPKFSISCETYICDVSKACKNLLFRYGGFC
QKIEADIRGA-GVLLDSDVSGLYSTIAAKTSSITP---TTDRF-----------N-----
--------------------VSQFFLPK-----VQS--------NSERFESRSV--IEDL
LFSKIETTGPGFY-GDYYNC---KKN-------AIQDLTCAQYHNGILVIPPVMDAETLG
MYGGIAAASLTLGIFG---GQ---AGITTWSLAMAGRLNALGVVQNALVDDVNKLANGFN
QLTASV--------------GKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS
TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVY
AQSLRNGFCGQ-GLHVLSLMQNAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGS----
--------KCIV----AKDGV----------LV--SA-----------NLSYWQWSPRNL
YKPENLTFANVIAVSR-GANYTTLNRTFDIPELNSTF--PIDEEFREYFQNM---SSELQ
ALK---NLTADMSKLNISAEIQ--------------LINEIAHNVSNMRVEVEKFQRYVN
YVKWAWWQWLIIFIALTLLAGLMLWCCLATGCC-GMCGC--LAATCASCCDCRG---TKL
QSY----------EIEKIHIQ----
>Swine
----------MKLFTVFTLLASIRV---------------------------------LY
GCESVDFNLFNT---IFS------------------------------------------
--THRGL-----------------------------------------------------
--------------------------------S-------NTTSVITG----AYPSTNK-
-----------------------------------------------------SDW----
--SCN-------------------------------------------------------
------------TRTGHLSGSGFGIG---LYVQTPREQYQYGGSGAGGYTIAVSPIHVT-
------------------------------NL--TW-----ELWIHRKW--------GVN
SVV--------------------------TVRLC--RWW------QFMSF--NSTSHAA-
----------------------------DAGPTNAFECLINGS-----------------
-YPTHRNTG-YMFGVTW----------------YNDLVRIVFPPTVLEMQLD---GLQW-
---------------ERVQFNSPV-----NAGHVTRFNVVK------DISTVLVETNSGG
SVFRYSYCADG-FVNGLQCKLRLFDIPPGVYSNSEVEY--PTALYTVVHNMSACPERP--
-----------DSYCGSNSCPFKRAVFS--NC----IVNYTTWVNPDQRDFQHL------
------------------ILPNGKFNPFT---------------------ECNGLNRIVD
G---------------CV---------PGF-------------VLRVGRGKA--------
----VNR-----TIV------TPYLKP---------------------------------
-------------------------YEC--------------------------------
------FGWSWN--------DNQDSIYDW--------------WIADFVSTG--------
-------------------------------------------------AFVCESN-P--
---------------------EAPKTGVCVTYTVEKVTFQGVLYE-SN----FTFAQYYN
LLYV---G--SQLRYVRIL-GKVYEVSSCFEASYDVLY---RNNQSFGLLYRSFDCNQLH
IK-SAR-----FVD----------RLLP---SHNGTATV----LGCLFNASYAPNDTMV-
---N--CTNPL----GDGFCADL--------------------LGNVAVRRMTFEKHDTT
YVAPV-TNERYTEMPLDHQLILTEQFLQTTMPKFSVSCETYICDVSKACKNLLFRYGGFC
QKVEADIRGA-GILLDGDVSSLYSTIAAKTSSVVP---TTDRF-----------N-----
--------------------VSQFFLPK-----TRS--------SANKYESRSA--IEDL
LFSKIETTGPGFY-GDYYNC---KKN-------AIQDLTCAQYHNGILVIPPIMDAETLG
MYGGIAAASVTLGIFG---GQ---AGMATWSVAMAGRLNALGVVQNALVDDVNKLANGFN
QLTASV--------------SKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS
TNFKVISQRLDKLEADVQMDRLINGRMHVLQLFVTNYKLKIAELRNTHRYVQSLINECVY
AQSLRNGFCGQ-GLHVLSLMQNAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGS----
--------KCIV----AKDGV----------LV--SA-----------NLSYWQWSPRNL
YKPENLTFANVIAVSR-GANYTTLNKTFDIPELNSTF--PIEEEFREYFQNM---SSELQ
VLK---NLTADMSKLNISAEIQ--------------LINEIAHNVSNMRVEVEKFQRYVN
YVKWAWWQWLLIFIALTLLAGLMLWCCLATGCC-GMCGC--LAATCASCCDCRG---TKL
QSY----------EIEKVHVQ----
>SADS
----------MKLFTVFTLLASIRV---------------------------------LY
GCESVDFNLFNT---IFS------------------------------------------
--THRGL-----------------------------------------------------
--------------------------------S-------NTTSVITG----AYPSTNK-
-----------------------------------------------------SDW----
--SCN-------------------------------------------------------
------------TRTGHLSGSGFGIG---LYVQTPREQYQYDGSGAGGYTIAVSPINVT-
------------------------------NL--TW-----ELWIHRKW--------GVN
SVV--------------------------TVRLC--RWW------QFMSF--NSTSHAA-
----------------------------DAGPTNAFECLINGS-----------------
-YPTHRNTG-YMFGVTW----------------YNDLVRIVFPPTVLEMQLD---GLQW-
---------------ERVQFNSPV-----NAGHVTRFNVVK------DISTVLVETNSGG
SVFRYSYCADG-FVNGLQCKLRLFDIPPGVYSNSEVEY--PTALYTVVHNMSACPERP--
-----------DSYCGSNSCPFKRAVFS--NC----IVNYTTWVNPDQRDFQHL------
------------------ILSNGKFNPFT---------------------ECNGLNRIVD
G---------------CV---------PGF-------------VLRVGRGKA--------
----VNR-----TIV------TPYLKP---------------------------------
-------------------------YEC--------------------------------
------FGWSWN--------DNQDSIYDW--------------WIADFVSTG--------
-------------------------------------------------AFVCESN-P--
---------------------EAPKTGVCVTYTVEKVTFQGVLYE-SN----FTFAQYYN
LLYV---G--SQLRYVRIL-GKVYEVSSCFEASYDVLY---RNNQSFGLLYRSFDCNQLH
IK-SAR-----FVD----------RLLP---SHNGTATV----LGCLFNASYAPNDTMV-
---N--CTNPL----GDGFCADL--------------------LGNVAVRRMTFEKHDTT
YVAPV-TNERYTEMPLDHQLILTEQFLQTTMPKFSVSCETYICDVSKACKNLLFRYGGFC
QKVEADIRGA-GILLDGDVSSLYSTIAAKTSPVVP---TTDRF-----------N-----
--------------------VSQFFLPK--TQSSAN-----------KYESRSA--IEDL
LFSKIETTGPGFY-GDYYNC---KKN-------AIQDLTCAQYHNGILVIPPIMDAETLG
MYGGIAAASVTLGIFG---GQ---AGMATWSVAMAGRLNALGVVQNALVDDVNKLANGFN
QLTASV--------------SKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS
TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSIINECVY
AQSLRNGFCGQ-GLHVLSLMQNAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGS----
--------KCIV----AKDGV----------LVSANL-------------SYWQWSPRNL
YKPENLTFANVIAVSR-GANYTTLNKTFDIPELNSTF--PIEEGFREYFQNM---SSELQ
VLK---NLTADMSKLNISAEIQ--------------LINEIAHNVSNMRVEVEKVQRYVN
YVKWAWWQWLLIFIALTLLAGLMLWCCLATGCC-GMCGC--LAATCASCCDCRG---TKL
QSY----------EIEKVHVQ----
>ApodemusAlpha
----------MALIFVLMLITLYRC---------------------------P-----FA
LCNFQVCTDQLR---QQEVYLPNAIS----------------------------------
------------------------------------------------------------
----------------------------------------NATYIATA----VFP-----
----------------------------------------------------TRHW----
--QCG--------------------------SSSNSTPVENKFNGIGV------------
------------------FVHRFNHP---NWWH-----------------FAAYPAAPT-
------------------------------NK--TW----ILFWWHR----------ATQ
AST--------------------------VFQVC--KYP------QPAVD--VLTSGYRC
ESPTNPPC--------------------SAIVNMAIECLINSTFRPTT------------
-FSF------SYVTWYN--------------------------SEINAVIHGQRFSFVYE
-GFLWSNASAFCYDGNGCIFNIPN-----------------------TTSDWLVSTDSSG
AINNFVDCGYD-YESQLKCKNLVFELEPAVYQGAA-----LPIESSV-YYVANDLADCAF
SFADIFSD---GTGN---YGGLRRHVFT--NC----WVNYTSWFLCDDGLACIIFNAIFS
EVVYNLTQPDGLINPFLRCNGLDVFTIVK-------------------------------
---------------GCS---------AGY----------------VLRYQL--------
----FDS-----GQF----NPDAYTPDY--------------------------------
-------------------------MEC-----------------F--------------
------GYFQID------------RSYIVYN--------------AKFITEG--------
-------------------------------------------------LTVCVLQ-P--
---------------------VEPELGVCKQYTIDGVTFQGILHT-SN----ANITTFHN
LLYY---G--DMVSHVRIK-GVVYSVEPCNSFYYSVL----KTRSEVGYLYSGANCNSSD
VV---T-----FSR----------RARA----RLLTDSS----LGCLVDVQLTNNNY---
---T-TCSHPI----GNGLCADV-------------NVTGMPVVGNIYIQP-----HDTD
YARPI-LSPQIISLPLDHVINVKEQFVQTSAPKFDVDCERYICDVSVQCKELLAKYGGYC
PKIVSDIKSS-SLQLDYQVQGIYKTLN--VDVKVP---DI-DF-----------G---A-
-FN-----------------FSM-FESE------PN--------G------RSF--IEDI
LFDKIVTTGPGFY-QDYYDC----KK----M--NLEDITCKQYYNGIMVIPPVMDDTLIT
FWSSAVAGSMTAGLFG---GQ---AGMVSWSIAVAGRLNALGVMQDALVNDVNKLANGFN
NLTQYV--------------ADGFKTTSQALSAIQSVVNNNAQQISQLVQGLSENFGAIS
NNFIVIAERLERLEAQLQMDRLINGRMNILQNFVTNYKLSISELKSQQILAQSLINECVY
AQSNRNGFCGD-GLHLFSLMQRAPDGIMFFHYTLVPNNTIDVETTPGLCLGN---N----
--------VCIA----PRDGL----------FV--KT---------NIRSDVWHFTTRNL
YNPQAITVNNSVVVNG-GVNFTSLNQTIEGIEP-PTI-PSFDEEFEDLYKNI---TLELE
QLK---NITFDPELLNLTYYID--------------RLDELSTNVSQLHVDISEFNKYVQ
YIKWPWYVWLAIFLVLVLFCFMLLWCCCATGCC-GCCGM--LGSACNGCCTKPQ------
-TV----------EFEKVHVQ----
>CoronaJC34
----------MALIFVLMLITLYRC---------------------------P-----FV
LCNFQVCTDQLR---QQEVYLPNAVS----------------------------------
------------------------------------------------------------
----------------------------------------NATYIATA----VFP-----
----------------------------------------------------TRHW----
--HCG--------------------------SSSNSTPGDNKFNGIGV------------
------------------FVHRFNHP---NWWH-----------------FAAYPAAPT-
------------------------------NK--TW----ILFWWHR----------ATQ
AST--------------------------VFQVC--KYQ------QPAVD--VLTSGFRC
EAPTNPPC--------------------SAIVNMAIECLINSTFRPTT------------
-FSF------SYVTWYN--------------------------SEINAVIHGQRFSFVYE
-GFLWSNASAFCYDANGCIFNIPN-----------------------TTSDWLVSTDSSG
AINNFVDCGFD-YESQLKCKNLVFELEPAVYHGAA-----LPIESSV-YYVANDLADCAF
SFADIFSD---GTGN---YGGLRRHVFT--NC----WVNYTSWFLCDDGLACIIFNAIFS
EVVYNLTQPDGLINPFLRCNGLDVYTIVK-------------------------------
---------------GCS---------AGY----------------VLRYQL--------
----FDS-----GQF----NPDAYTPDY--------------------------------
-------------------------MEC-----------------F--------------
------GYFQID------------RSYIVYN--------------AKFITEG--------
-------------------------------------------------LTVCVLQ-P--
---------------------VEPELGVCKQYTIDGVTFQGILHT-SN----ANITTFHN
LLYY---G--DMVSHVRIK-GIVYSVEPCNSFYYSVL----KTRSEVGYLYSGANCNSSD
VV-TFS------------------RRAR---ARTLTDSS----LGCLVDVQLTNNNYT--
---T--CSYPI----GNGLCADV-------------NVTGMPVVGNIYIQP-----HDTD
YARPI-LSPQIVSLPLDHVINVKEQFVQTSAPKFDVDCERYICDVSVQCKELLAKYGGYC
PKIVSDIKSS-SLQLDYQVQGIYKTLN--VDVKVP---DV-DF-----------G---A-
-FN-----------------FSM-FESE------PN--------G------RSF--IEDI
LFDKIVTTGPGFY-QDYYDC----KK----M--NLEDITCKQYYNGIMVIPPVMDDTLIT
FWSSAVAGSMTAGLFG---GQ---AGMVSWSIAVAGRLNALGVMQDALVNDVNKLANGFN
NLTQYV--------------ADGFKTTSQALSAIQSVVNNNAQQISQLVQGLSENFGAIS
NNFLVIAERLERLEAQMQMDRLINGRMNILQNFVTNYKLSISELKSQQILAQSLVNECVY
AQSNRNGFCGD-GLHLFSLMQRAPDGIMFFHYTLVPNNTIDVETTPGLCLGN---N----
--------VCIA----PRDGL----------FV--KT---------NIRSDVWHFTTRNL
YNPQAITVNNSVIVNG-GVNFTSLNQTIEGIEP-PTI-PSFDEEFEDLYKNI---TLELE
QLK---NITFDPELLNLTYYID--------------RLDELSTNVSQLHVDISEFNKYVQ
YIKWPWYVWLAIFLVLVLFSFMLLWCCCATGCC-GCCGM--LGSACNGCCTKPQ------
-TV----------EFEKVHVQ----
>UKRn3
------MIPMIKLNMYFLLFLLFVS-----------------------------------
----------AD---AVIQTCPAPGNVNLDISKL--------------------------
--------------YYGTH-----------------------------------------
----------------------------------------ASINATSQ----VVQVLPQ-
-----------------------------------------------------IPW----
--KCN--------------------------SYSNGASNKFNGIGVFV------------
----------------DLAPAAH------SWHL-----------FVYPSMPTNKTWILS-
------WA----------------------DTDTSF---------------------AGG
TMA-------------------SGIS---YVQIC-----------KYPAN--VVTDITNG
NGCHANHAGAG-----------------ATTCDVILRSPLECVLNRT-------------
-YSQQYAGV-SYITWYN------------------------------DHIIASIQGEVFT
-----FDIGEVL---QWSNFSAFC-----GTMQKCGFSYAT------TPSEWLVRTDNDG
TVIDYVICDTD-FESQLKCKNMVFELTPAVYSGSAVEL--QSAIYYVANELPD----CDF
SFSDVFMD---GTGN---FEGLRRHVFS--NC----WVNYTAWFACADDYACIIFNAIFA
EVRYNLSQPDGLVNPFIKCNGLDLYSITK-------------------------------
---------------GCS---------SGF----------------VLRYQF--------
----YAN-----GSF----DVNSYIPDY--------------------------------
-------------------------MEC-----------------F--------------
------GYFSLY------------NGYVIYN--------------AKFVSNG--------
-------------------------------------------------LTVCVVQ-P--
---------------------VEPELDVCKSYTIDGVTFQGILRN-TT----QQIDSFHN
ILYY---G--DMVSYVRIK-GVVYAVESCNRFYYSVF----KTLSDIGYLYSGATCDSTD
VT---T-----FMT----------KARA----TTFVDSS----LGCFIDVSVTDGNY---
---T-DCLNPI----GNGLCVDV-------------NVTGQPVVGNIFIQT-----HDTD
YARPI-LTAQQIELPIDHYVSVKEQFIQTSTPKFDVDCERYICDVSSDCRELLVKYGGYC
SKILADIKSS-SIQLDYQILGLYKTLA--VDFKVP---DI-EF-----------G---D-
-FN-----------------FSM-YMSE------AN--------G------RSF--IEDL
LFDKIVTTGPGFY-QDYYDC----KK----M--NLQDLTCKQYYNGIMVIPPVMDDTLIT
FWSSAVAGSMTAGLFG---GQ---AGMVSWTVALSGRLNALGVMQDALVEDVNKLANGFN
NLTQYV--------------ADGFKTTSQALSTIQAVVNNNAQQVSQLVQGLSENFGAIS
NNFALIAERLERIEAAMQMDRLINGRMNILQNFVTNYKLSISELKSQQALAQSLINECVY
AQSSRNGFCGD-GLHLFSLMQRAPDGIMFFHYTLKPNNTIIVDTTPGLCLSN---D----
--------VCIA----PKDGL----------FV--RL--------PTTRDTDWHFTTRNR
YSPEPITVNNTLTISG-GVNFTAVNSTIDGIEP-PAN-PSFDEEFAELYNNI---TLELE
QLK---NISFDPAKLNLTYYID--------------RLDELATNVSQLHVDVSEFNKFVQ
YIKWPWYVWLAIFLVLVLFSFLMLWCCCATGCC-GCCGL--CGAACNGCCTKPQ------
-PI----------EFEKVHIQ----
>LuchengRat
----------MYFFLLLLFVSADAA---------------------------------IQ
TCPAPG---------NVNLDISKL------------------------------------
--------------YY--------------------------------------------
----------------------------------------GTQASINA----TFQVVQV-
--------------------------------------------------LPQVPW----
--KCN--------------------------SYSNGPSNKFNGIGVFV------------
-------------------DLASAQH---SWHL-----------FVYPSMPTNKTWILS-
------WA----------------------DTHTSF---------------------EHG
SVI-------------------------SYVQIC-----------KYPSN--VVTDITNG
NGCHTNMAGPG-----------------ATTCDVILSSPLECVLNRT-------------
-YSQQYAGV-SYITWYN------------------------------DHIIASIQGEVFT
-----FDIGEVL---QWSNFSAFC-----GTGNKCGFSYAT------TLSEWLVRTDNDG
TVIDYVICDTD-FESQLKCKNMVFELTPAVYSGSAVEL--QSAIYYVSNELPD----CDF
SFADMFMD---GTGN---FEGLRRHVFS--NC----WVNYTAWFACADDYSCIIFNAIFA
EVRYKLSQPDGLVNPFIKCNGLDLYSITK-------------------------------
---------------GCS---------SGF-----------VLRYQLYANGS--------
----FDV-----NSY----T-PDY------------------------------------
-------------------------MEC-----------------F--------------
------GYFALY------------NGYVIYN--------------AKFVSKG--------
-------------------------------------------------LTVCVVQ-P--
---------------------VEPELDVCKSYTIDGVTFQGILRN-TT----HQIDSFHN
ILYY---G--DMVSYVRIR-GVVYAVESCNRFYYSVF----KTLSAIGYLYSGATCDSTD
VT---T-----FMT----------KARA----TTFVDSS----LGCFIDVSVTDGNY---
---T-DCLNPI----GNGFCVDV-------------NVTGQPVVGNIFIQT-----HDTD
YARPI-LTAQQIELPIDHYVSVKEQFIQTSTPKFDVDCERYICDVSSDCRELLVKYGGYC
SKILADIKSS-SIQLDYQILGLYKTLA--VDFKVP---DI-DF-----------G---D-
-FN-----------------FSM-YMSE------AN--------G------RSF--IEDL
LFDKIVTTGPGFY-QDYYDC----KK----M--NLQDLTCKQYYNGIMVIPPVMDDTLIT
FWSSAVAGSMTAGLFG---GQ---AGMVSWTVALAGRLNALGVMQDALVEDVNKLANGFN
NLTQYV--------------SDGFKTTSQALSTIQAVVNNNAQQVSQLVQGLSENFGAIS
NNFALIAERLERIEAAMQMDRLINGRMNILQNFVTNYKLSISELKSQQALAQSLINECVY
AQSSRNGFCGD-GLHLFSLMQRAPDGIMFFHYTLKPNNTIIVETTPGLCLSN---D----
--------VCIA----PKDGL----------FV--RL--------STARDTDWHFTTRNR
YSPEPITVNNTLTISG-GVNFTVVNSTIDGIEP-PAN-PSFDEEFAELYKNV---TLELE
QLK---NISFDPEMLNLTYYID--------------RLDELATNVSQLHVDVSEFNKFVQ
YIKWPWYVWLAIFLVLVLFSFLMLWCCCATGCC-GCCGL--CGAACNGCCTKPQ------
-PI----------EFEKVHVQ----
>LongquanAlpha
------MIPMTKLNMYFLLLLLFVS-----------------------------------
----------AD---AVIQTCPAPGNVNLDISKL--------------------------
--------------YYGTQ-----------------------------------------
----------------------------------------ASINATSQ----VVQVLPQ-
-----------------------------------------------------IPW----
--KCN--------------------------SYSNGPSNKFNGIGVFV------------
-------------------DLASTAH---SWHL-----------FVYPSMPTNKTWILS-
------WA----------------------DTDTSF---------------------EYG
SGI-------------------------SYVQIC--KYP------SIVVT--DITNGNGC
HANMAGAG--------------------ATTCDVILRSPLECVLNRT-------------
-YPQQYAGV-SYITWYN------------------------------DHIIASIQGEVFT
-----FDIGEVL---QWSNFSAFC-----GTRQKCGFSYAT------TPSEWLVRTDNDG
TVIDYVICDTD-FESQLKCKNTVFELTPAVYSGSAVEL--QSAIYYVANELPD----CDF
SFADIFMD---GTGN---FEGLRRHVFS--NC----WVNYTAWFACADDYACIIFNAIFA
EVRYNLSQPDGLVNPFIKCNGLDLYSITK-------------------------------
---------------GCS---------SGF----------------VLRYQF--------
----YAN-----GSF----DVNSYTPDY--------------------------------
-------------------------MEC-----------------F--------------
------GYFALY------------NGYVIYN--------------AKFVSSG--------
-------------------------------------------------LTVCVVQ-P--
---------------------VEPELDVCKSYTIDGVTFQGILRN-TT----HQIDSFHN
ILYY---G--DMVSYVRIK-GVVYAVESCNRFYSSVF----KTLSALGYLYSGTTCDSTD
VT----------------------TFMTKARATTFVDSS----LGCFIDVSVTDGNYT--
---D--CLNPI----GNGLCVDV-------------NVTGQPVVGNIFIQT-----HDTD
YARPI-LTAQQIELPIDHYVSVKEQFIQTSTPKFDVDCERYICDVSSDCRELLVKYGGYC
SKILADIKSS-SIQLDYHILGLYKTLA--VDFKVP---DI-DF-----------G---D-
-FN-----------------FSM-YMSE------AN--------G------RSF--IEDL
LFDKIVTTGPGFY-QDYYDC----KK----M--NLQDLTCKQYYNGIMVIPPVMDDTLIT
FWSSAVAGSMTAGLFG---GQ---AGMVSWTVALAGRLNALGVMQDALVEDVNKLANGFN
NLTQYV--------------TDGFKTTSQALSTIQAVVNNNAQQVSQLVQGLSENFGAIS
NNFALIAERLERIEAAMQMDRLINGRMNILQNFVTNYKLSISELKSQQALAQSLINECVY
AQSSRNGFCGD-GLHLFSLMQRAPDGIMFFHYTLKPNNTIIVETTPGLCLSN---D----
--------FCIA----PKDGL----------FV--RL--------TTARDTDWHFTTRNR
YSPEPITVNNTL-ITSGGVNFTAVNSTIDGIEP-PAN-PSFAEEFAELYKNV---TLELE
QLK---NISFDPEMLNLTYYID--------------RLDELATNVSQLHVDVSEFNKFVQ
YIKWPWYVWLAIFLVLVLFSFLMLWCCCATGCC-GCCGL--CGAACNGCCTKPQ------
-PI----------EFEKVHVQ----
>EidolonBat
----------MVVLLFAIFSVASAL-------------------------DPN-----RT
ACVANYGSSYLP---SSITSVALSDVNFLSRVVP--------------------------
--------------EFDIA-----------------------------------------
----------------------------------------RTSLVVRQ----SLYVASV-
-----------------------------VFDKISVT------------PPAGQLYNDTS
V------------------------------AFGDGIFVNVHMYRRLQ------------
-------GITDSNLKYCQEPFGVAFG---NTFV---QEPIVIIIIAPGNYGRLPALQIP-
------------------------------TI--AT---------------------VTI
AVC-------------------------SNGTLC--RNP---VLPRWGTS--GNIVVNDA
LKCFGSITYFD-----------------QKNISYTEAASRFN------------------
-FAFLHEDG-NILTYYA--------------------SIGAALNISAPYRFV-PYRRVPA
-GFNPSVAQFFQVYTRPIPYDRTC-----QVYNVSWYSSPL------SKQDVLVSYDNQS
SIIDAASCSSD-ATSELKCILTTFDPPNGVYSLSNY----RSQPSAI-VRLSSADGICNV
NYTHFL-----RPPL---PFYWRRFQIK--SC-----KFDFNTLVSALPTYDLWCKGISP
ERLGSMCFGAVTLDSM--LINTTHYNDLK--SNVPDAFTRFNYKLPTNFYGCVHTYYLND
S--------------SFN---------YAV----------------VNDPGW--------
----FQE--------------IRP------------------------------------
-------------------------GGRPDNPGY----------LN--------------
------TLAYKA----------ASCNEKCFG------------MIVISLTIA--------
----------------------------------------------SGNTMVCPVG----
------ND-------------TNVISGVCVNYNIYGYQGTGVISN--S----SAVIPGSK
VFSLSSHG--DVSLFKY--NNKVYALYPCAYAPITAAF---YAGYNTSLLFNNLQCDLRA
RA--IYEPTS-PYW----------RITQ--QATNAFDTS----AGCVYNAINATNITVS-
---D--CSLLL----GDSYCLRP---------TVSARTLGGESMLELVLYD--PLYDSLV
PITPV----YQIDVPTNFTLAATTEYIQTYASKISIDCSKYLCGDSVQCKNVLLQYGTFC
NDVNTALTRV-FSLLDTALVETVSSLKSTAPADLA-------Y-T---------G---D-
-FN-----------------FTS-LVGC-------------LGTSCNQNSYRSA--LSDL
LFNKVSVADPGFM-QAYQKC----LDSQWGG--NIRDLICTQSFNGISVLPPIVSPSMQA
LYTTALVGGIAASGFT---FGVSSAAVIPFATQLQFRLNGLGVTTNVLMENQKLIANAFN
KALVSI--------------QTGFEATNQALNKIQTVVNHNALQLQALVQQLGNTFGAIS
SSVNEIFSRLDQLEANAEVDRLISGRMVVLNTYVTQLLIQASELRSQAQLANQKMSECVK
AQSSRNDFCGN-GTHVFSIPQVAPNGMLFIHYSYQPTEYKQLYTTAGLCFNG---T----
---------GYV----PKDGL----------FVREDN-----------TSTVWYFTKAAF
YSPSNLSYDNTRQLDSCGVNYTVVNNTVLTPFEPPNF--NFDEEFDKYFKNQ--SSQLNI
TFD---SSQFNATLLDLSGQMK--------------TLDQVVKELNESFINLKELGVYTQ
TIKWPWYAWLGMIAGLVGLAMAVFMLCCMTNCCSGLKGICSCKQC--QYDDYAD------
-VY----------PAVRVSGKRTV-
>BATGCCDC1
---------MFRTLLLAALFNACWC---------------------------A-----RP
TCIKP----------TETWGTP--------------------------------------
--SFTGVEYVPHNTTYVSV--------------------------PLN------------
----------------------------------------KLSCLLPDP---YMAHSGQ-
-----------------------------TVRQKLYM---------------GNTSNTLV
YPVTP--------------------------PMFNLTYGNVTPGVYNTSFLPVFDGLLVH
TYMNRFAHLDNPNRTCQE-PFGVVFG---TTFE-----QDRIAMVIIAPGEFGMWGQVN-
------------------------------RPNTTF---------------------VHV
VAC-------------------------SNATIC--AYP------MFNRW--GPAGSIHA
ENSFVEH---------------------NSSCFLNDTFEIPMGTSRVN------------
-LAFRFQDG-NLLLYHT-----------AWLPTENYTLSGDYP---LRYARSVGVGSNLP
FAQFFQSVARARD--SACAFLHNN-----------LYIAPV------QPKELLVKYNDQG
MPVEIADCSAD-STQELYCITGTFTPSVGVYQLSRY----RAEAKKL-VQVTQQEDSCAI
PYTTIL-----EPPS---PAAWVRATIS--NC-----TFDFESLLRTLPTYNLKCYGISP
ARLSTMCYAGVTLDIF--KLNTTHLSNML--GSVPDAVSIYNYALPSNFYGCVHAYHLNS
T---------------TP---------YAVAVPPGAYPIKPGGRQLFNSFVS--------
------------QVL----D-SPT------------------------------------
-------------------------SQC--------------------------------
------------------------TPANCMG------------VVVIGLTPA--------
----------------------------------------------SGSNLVCPKA----
------ND-------------TQVIEGQCVKYNFYGYAGTGVINQ-SD-----LAIPNNK
LFVTSKSG--AVLAVR--AGDKVYSITPCVSVPISVGY---DPGHQRALVFNGLDCSARA
NAVSMPASEYWTAA----------ASTTARGSEPVLDTP----SGCVYNVNNCTTHTVS-
---V--CEMPI----GNSLCLVS--NFTCSDVATASLSPNLLSLVVYDPTD-----AGLK
VLTPV----YWVSIPTNFTLAATTEYIQTTAPKVNVDCVKYLCGDSERCIDVLSQYGAFC
EDVNKALADV-SAIIDSSMVTMVSELTAGVMWSET---PQANV-----------G---S-
-YN-----------------FSG-LMGC-------------LGSNCQEKQYRSA--ISDL
LYNKVKVADPGFM-GAYQKC----IDEQWGG--SVRDLICTQTFNGISVLPPIVSPGMQA
LYTSLLVGAVASSGYT---FGITSVGVIPFATQLQFRLNGLGVTTNVLMENQKLIANAFN
NALTGI--------------QKGFDATNMALAKMQSVINQHAQQLSTLVDQLGNSFGAIS
SSINEIFSRLDELEANAQVDRLINGRMVVLNTYVTQLLIRASEVKAQAALASQKISECVK
AQSQRNDFCGN-GTHVLSIPQMAPNGVLFLHYSYQPTAYNLVRTAAGLCFND---T----
---------GYA----PLGGL----------FVLPNN--------TD----RWLFTKMSF
YDPVNISVSNTQVLAACGLNYSSVNYTVLEPAVDTSS-FNFTEEFEKWYVNQ--SHIFNN
TFN---ASAFNFSLVDVNEQLA--------------ILTDVVNQLNQSYIDLKQLGTYEY
TVKWPWYVWLGMIAGLVGLVLAVVLLLCMTNCCSCARGVCSCKSCA--YEEHED------
-VY----------PAVRVHGKRTA-
>BAT2006
----------MRLIVVLSLALIACD---------------------------A-----SA
TRPECFDNSNFQ---LHPLNHTVNTTSLVV------------------------------
--NVVNLLLPDPYIAYSGQ--------------------------TLR------------
----------------------------------------QNLFMADLSRTMIYPITPP-
----------------------------------------------------AKDRNGGY
IYNTT----------------------IL--SVASGLFVHTWMYRQDS------------
-----------ASTKYCQEPFGVAFG---DTFI---------------QDRIAIVVIAP-
------------------------------DRLGSW---AQSTYRSVTT--------VHL
VVC-------------------------SNATLC--INP------GFNRW--GPAGNIIA
SNALVDH---------------------SNSCFVNNSFNVNISTSRIN------------
-LAFLFKDG-DLLVYHS-----------NWLPKGSFDFNQSFP--LQYFMTL-PVGGNLP
RAQFFQSIVRQGGTNNGVDDQCTD-------FNINLHIAHL------VNRDLLVSYFDNG
SVANAADCADS-ASQELYCVTGSFQPPTGVYPLSRY----RAQVDGF-VRVTQRGAYCRP
PYNALL-----DPPQ---PVVWRRFMLY--DC-----AFDFSVVIDNLPTHQLQCYGISP
RRLASMCYSSVTIDVM--RINATHLNNLL--NRVPDSFSLYNYAVPDDFYGCLHAFYLNS
T---------------TA---------YAV--------------ANQFRINP--------
----GGR-----QSN------SAY------------------------------------
-------------------------IAT----------------VL--------------
------NAAEYA------------KSYFMYG------------LAVITLKPA--------
----------------------------------------------SGNKLVCPIA----
------ND-------------TDIITDRCVQYSLYGYTGTGVLST-NT----SLTVPKGK
VFTASSTG--AIIGV--FINGTMYSITPCVTVPVSVGY---HANFERVLLFNGLSCSQRS
RAVSRP--TS-TLW----------SLSV--SDGSAIDTL----SGCVVNAILRNGTTVS-
---T--CSMPL----GNSLCLIN-------DTTVAVARAAGLPRLYLVNYDPLYDNNSAT
PMTPV----YWVKIPTNFTLTATDEFIQTNAPKVTIDCARYLCGDSSRCLNVLLHYGTFC
DDINKALAKV-NTILDGALLSLS------KELSINTRDEIQSF-AF------G-G---D-
-YN-----------------FTG-LMGC-------------LGPNCGATTYRSA--LSDL
LYDKVKITDPGFM-QSYQKC----IDSQWGG--SVRDLLCTQTYNGIAVLPPIVSPAMQA
LYTSLLVGAVASSGYT---FGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFN
NALVNI--------------QKGFTETSIALSKMQDVINQHAAQLQTLVTQLGNSFGAIS
SSINEIFSRLEGLAANAEVDRLINGRMMVLNTYVTQLLLQASEAKAQNALAIQKISECVK
AQSLRNDFCGN-GTHVLSIPQLAPNGVLFIHYAYTPTDYALVQTSAGLCYNG---T----
---------GYA----PLRGM----------FVLPNN--------TN----MWHFTSMQF
YNPVNISYSNTQILTSCSVNYTSVNYSVLQPSAPSDY--DFQKEFDKFYKNL--STSFNN
TFN---PNDFNFSMVDVTAQIT--------------SLHQVVNQLNQSFIDLKKLNVYEK
TIKWPWYIWLAMIAGIVGLVLAVIMLMCMTNCCSCFKGMCDCRRCCGSYDSYDD------
-VY----------PAVRVNKKRTV-
>BATHKU9
----------MLLILVLGVSLAAAS---------------------------------RP
ECFNPRFTLTPL---NHTLNYTSIKAKV--------------------------------
------------------------------------------------------------
----------------------------------------SNVLLPDP----YIAYSGQ-
-----------------------------TLRQNLFMA----------------------
-------------------------------DMSNTILYPVTPPANGA------------
------NGGFIYNTSIIPVSAGLFVN---TWMY---------RQPASSRAYCQEPFGVAF
GDTFENDRIAILIMAP--------------DNLGSWSAVAPRNQTN-----------IYL
LVC-------------------------SNATLC--INP------GFNRW--GPAGSFIA
PDALVDH---------------------SNSCFVNNTFSVNISTSRIS------------
-LAFLFKDG-DLLIYHS----------GWLPTSNFEHGFSRGSHPMTYFMSL-PVGGNLP
RAQFFQSIVRS----NAIDKGDGM----CTNFDVNLHVAHL------INRDLLVSYFNNG
SVANAADCADS-AAEELYCVTGSFDPPTGVYPLSRY----RAQVAGF-VRVTQRGSYCTP
PYSVLQ-----DPPQ---PVVWRRYMLY--DC-----VFDFTVVVDSLPTHQLQCYGVSP
RRLASMCYGSVTLDVM--RINETHLNNLF--NRVPDTFSLYNYALPDNFYGCLHAFYLNS
T---------------AP---------YAV--------------ANRFPIKP--------
----GGR-----QSN------SAF------------------------------------
-------------------------IDT----------------VI--------------
------NAAHYS------------PFSYVYG------------LAVITLKPA--------
----------------------------------------------AGSKLVCPVA----
-------ND------------TVVITDRCVQYNLYGYTGTGVLSK-NT----SLVIPDGK
VFTASSTG--TIIGV--SINSTTYSIMPCVTVPVSVGY---HPNFERALLFNGLSCSQRS
RAVTEP--VS-VLW----------SASA--TAQDAFDTP----SGCVVNVELRNTTIVN-
---T--CAMPI----GNSLCFIN-----GSIATANADSLPRLQLVNYDPLY---DNSTAT
PMTPV----YWVKVPTNFTLSATEEYIQTTAPKITIDCARYLCGDSSRCLNVLLHYGTFC
NDINKALSRV-STILDSALLSLVK------ELSINTRDEVTTF-SF------D-G---D-
-YN-----------------FTG-LMGC-------------LGPNCGATTYRSA--FSDL
LYDKVRITDPGFM-QSYQKC----IDSQWGG--SIRDLLCTQTYNGIAVLPPIVSPAMQA
LYTSLLVGAVASSGYT---FGITSAGVIPFATQLQFRLNGIGVTTQVLVENQKLIASSFN
NALVNI--------------QKGFTETSIALSKMQDVINQHAAQLHTLVVQLGNSFGAIS
SSINEIFSRLEGLAANAEVDRLINGRMMVLNTYVTQLLIQASEAKAQNALAAQKISECVK
AQSLRNDFCGN-GTHVLSIPQLAPNGVLFIHYAYTPTEYAFVQTSAGLCHNG---T----
---------GYA----PRQGM----------FVLPNN--------TN----MWHFTTMQF
YNPVNISASNTQVLTSCSVNYTSVNYTVLEPSV-PGD-YDFQKEFDKFYKNL--STIFNN
TFN---PNDFNFSTVDVTAQIK--------------SLHDVVNQLNQSFIDLKKLNVYEK
TIKWPWYVWLAMIAGIVGLVLAVIMLMCMTNCCSCFKGMCDCRRCCGSYDSYDD-----V
YPA---------VRVNKKRTV----
>Zhejiang2013
--------MVARYRLCILQLILSAC----------------------------------H
LSITRDVQPYVH---EANCTKQVATEGPFMAAYPL-------------------------
--GKYGFINT----YYPDR--------------------------IFR------------
--------------------------------S-------NTTALFTD----LFPVIGT-
----------------------------TVTPWKAFN------------ALTTNERKDKR
NFERH--------------------------PFGEGVFVTIKHTQVS-------------
---------------GPSTPPMYLFG---TYFN-----------------SSSYTLAIS-
------------------------------LD--GL-----Y---------------RRI
EVC--------------------------NFQVC--QNP------VMYYA--KVSNPAQG
NPLIYSQRAYTD----------------YNSCVSQTSQSFNITSQGDKNGAFSKDTITT-
-YVFKYQNG-IFSVFHG---------------FHNGTDHVPYPKPAFEFPLDIPI-----
---THFIIPPTV---EEPAQGQGY-----TRGNYVVYYAQL------KKSTFMFGFDSNG
LITRYIDCAAG-PKDELMCSQGSFNITPGVYTTTNYRA--TPKQHVV-ITSADVSAEC--
PFQSLINVTEATIPS---PAFWRRHYVR--NC-----NYDISVFTDNADVYSLQCYGVAP
SSLADMCWEEAHIDYM--KISEKDIFSFK--PSGAGDFAKYNYKLPSDFMGCTVVFTNQE
L--------------TCNATSGQLCHVYT---------------NNLTNYPAEATAWDKS
HYESIER-----YQM----W-SSENV----------------------------------
-------------------------YNCELQEVG----------PQ--------------
-------QFNRMPRNCYVRSNNSNDYWQPMS---FRGVNSLMVAMAITLKPT--------
----------------------------------------------RTSATVCGYK----
-QKT-----------------TPLVLNECITYHIYGYKGTGVIVS-AN----YTFQ-SFQ
TVQLTSTG--SLHSFKY--NNTIYGILPCAQAQVSIVTAG-SNHDNVAVVYNGLGCNAFQ
SK-MQG--VDNTEW----------SVYT------NFSSPIDTPVGCLTGAIQAQENST--
---E--CQFAL----GLDSCVNY---TADTRLRTARAADRALTFNYMYFAQ----ELPSQ
SEQSVAFDNSTLQIPINFTIGIEYETIPVTMPKVTVDCAQYVCGDNSECRTLLVQYGTFC
ETINDALRGV-ALQQDVNQKDVFSSVR--RLAKVSSPMNLGNL-N---------G-----
-FN-----------------FSS-ILNQ--EAINGN-----------NFQARSA--IEDL
FFDKIETADVGFQ-KKYDEC----TG---GS--VVKDLGCAQSFNGLMVLPPQMTDAHVA
AYTTS----AALGSFF----------SIPNTMQMAYRFNGIAVTQKVLVDNQKQIANKFN
QAMMSV--------------QTGFKATSSALEKLQKVVNDNAQALNNLVAQLTNNFGAIS
SAINDITQRLDKLEADAQIDRLINGRLQVLQTFVTQQLIRASEIRASAKLAAQKMSECVQ
GQSQRLDFCGR-GMHLMSFPQAAPYGMVFLHVLYKPTDYINVTTVPAICSND--------
--------VAYF----PVDGV----------FVYYNN--------------SLMFTKRNY
FEPEIITIDNIRSAGSCNVDVTYVNHTIYNPEM-PEL-EDFKQELEEIRKNFSTGLPNRP
NFTLPGLEGINASMVDLSEEVK--------------ILNDVVKELNASLINLQELGVNSQ
YIKWPWYIWLGFIAGLIAIVMATIMLCCMTSCCSCFKGLCACKRCCDSFDEPDE------
--------------PIKYHYP----
>Beta04
----------MFILLLLPIVLAQQD-----------------------------------
SC-------------NHIVQLPNS------------------------------------
--MVRGVYNSGSKVYYPDDINRV-------------------------------------
----------------------------------------STSILFND----YFLPFNS-
-----------------------------NLTNRQTL---------------GNTNNNRF
DVFTE--------------------------PFLDGVYFAATEHSNVL------------
--------------------RGWIFG---TSFT----------------NTTQSALFYN-
------------------------------NG--TN---------------------VVI
EVC--------------------------NFNFC--LVP------RVHA---LPNGSSIS
YIYTS-----------------------KANCTYTYVSQSFSLNGAICSSNCDKFKDFRE
-FIFKYSEG-FLHVYSG------------YKAISQGNGFVPSFSALKPFGKF-PIGILVT
N----FSVILTSFYHDSTTTKLAA---------SSLFYGHL------RPITMLLQYDENG
TIYNAIDCSQD-PLSELKCSLKAVNVSKGIYQTSNFRV--TPSQSVA--RYPNITNLC--
PFSQVFNAT--RFPS---VYAWTRERIS--NC-----IADYSVLYNSTSFSTFRCYGVSP
TKLNDLCFSNVYADSM--VVRGDEVRQIA--PSQTGVIADYNYKLPDDFTGCVIAWNSKA
K----------DENGQYF---------YRL--------------FRKSKLLP--------
----FQR-----DVS----N-VTYGSGKN-------------------------------
-------------------------DGCNPSEAD-------CYWPL--------------
------LKYGFT--------SSVSQDYQPYR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-RS------------------TELVYNKCVNFNFNGLTGVGVLTN-SS----KKFL-PFQ
QYGRDNSD--FVNAVRDPPTNAILDITPCSFGGVSVITPGTNLTNEVAVLYQDVNCTDVP
TL-LSLNDYN-VGW----------RVYS--TGTSRFQIQ----AGCLIGAQYQNVTK---
---E--CDIPI----GAGVCASY------------TTKARTSSTPALFAYT-----MSLG
ATQSPAYANNTVLIPTNFSVSVITEVLPVSMAKTAIDCNMYICGDSTECSRLLLQYGSFC
EQLNRALAGV-ALEQDKNTQDVFAQVK--AVYKTP---TFTDF-G---------G-----
-FN-----------------FSS-VLPQ--PG-KPS--------Q------RSF--IEDL
LFNKVTLSDAGFM-KEYGNC----LG---DV--AARDLICAQKFNGLTVLPPLLTDEMIA
QYTSSLVGGTIASGWT---AGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFN
NAITQI--------------QSSLTTTSTALSKLQDVINQNANALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSAQTYVTQQLIKAAEVRASANLAATKMSECVL
GQSKRVDFCGK-GFHIMSFPQAAPHGVVFLHMNYIPSSERNFTTVPAICHEG---R----
---------AYF----PREGV----------FI--ND--------NG----NWSITPRNY
YAPSPITTENTFMSGSCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKFFKNH---TSPDL
DLE--DVSKLNASVVDINKEIE--------------KLNNIAQQLNSSLIDLQELGKYEQ
YLKWPWYIWLGFIAGLIAIIMASIMLCCMTSCCSCFKGLCSCGLCCKFDDDSEP------
-VL----------QGVKLHYT----
>Beta08
----------MFILLLLPIVLAQQD-----------------------------------
SCNHIVQLPNSM------------------------------------------------
---VRGVYNSGSKVYYPDDINRV-------------------------------------
----------------------------------------STSILFND----YFLPFNS-
-----------------------------NLTNRQTL---------------GNTNNNRF
DVFTE--------------------------PFLDGVYFAATEHSNVL------------
--------------------RGWIFG---TSFT----------------NTTQSALFYN-
------------------------------NG--TN---------------------VVI
EVC--------------------------NFNFC--LVP------RVHA---LPNGSSIS
YIYTS-----------------------KANCTYTYVSQSFSLNGAICSSNCDKFKDFRE
-FIFKYSEG-FLHVYSG------------YKAISQGNGFVPSFSALKPFGKF-PIGILVT
N----FSVILTSFYHDSTTTKLAA---------SSLFYGHL------RPITMLLQYDENG
TIYNAIDCSQD-PLSELKCSLKAVNVSKGIYQTSNFRV--TPSQSVA--RYPNITNLC--
PFSQVFNAT--RFPS---VYAWTRERIS--NC-----IADYSVLYNSTSFSTFRCYGVSP
TKLNDLCFSNVYADSM--VVRGDEVRQIA--PSQTGVIADYNYKLPDDFTGCVIAWNSKA
K----------DENGQYF---------YRL--------------FRKSKLLP--------
----FQR-----DVS----N-VTYGSGKN-------------------------------
-------------------------DGCNPSEAD-------CYWPL--------------
------LKYGFT--------SSVSQDYQPYR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-RS------------------TELVYNKCVNFNFNGLTGVGVLTN-SS----KKFL-PFQ
QYGRDNSD--FVNAVRDPPTNAILDITPCSFGGVSVITPGTNLTNEVAVLYQDVNCTDVP
TL-LSLNDYN-VGW----------RVYS--TGTSRFQIQ----AGCLIGAQYQNVTK---
---E--CDIPI----GAGVCASY------------TTKARTSSTPALFAYT-----MSLG
ATQSPAYANNTVLIPTNFSVSVITEVLPVSMAKTAIDCNMYICGDSTECSRLLLQYGSFC
EQLNRALAGV-ALEQDKNTQDVFAQVK--AVYKTP---TFTDF-G---------G-----
-FN-----------------FSS-VLPQ--PG-KPS--------Q------RSF--IEDL
LFNKVTLSDAGFM-KEYGNC----LG---DV--AARDLICAQKFNGLTVLPPLLTDEMIA
QYTSSLVGGTIASGWT---AGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFN
NAITQI--------------QSSLTTTSTALSKLQDVINQNANALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSAQTYVTQQLIKAAEVRASANLAATKMSECVL
GQSKRVDFCGK-GFHIMSFPQAAPHGVVFLHMNYIPSSERNFTTVPAICHEG---R----
---------AYF----PREGV----------FI--ND--------NG----NWSITPRNY
YAPSPITTENTFMSGSCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKFFKNH---TSPDL
DLE--DVSKLNASVVDINKEIE--------------KLNNIAQQLNSSLIDLQELGKYEQ
YLKWPWYIWLGFIAGLIAIIMASIMLCCMTSCCSCFKGLCSCGSCCKFDDDSEP------
-VL----------QGVKLHYT----
>Beta05
----------MFILLLLPIVLAQQD-----------------------------------
SCNHIVQLPNSM------------------------------------------------
---VRGVYNSGSKVYYPDDINRV-------------------------------------
----------------------------------------STSILFND----YFLPFNS-
-----------------------------NLTNRQTL---------------GNTNNNRF
DVFTE--------------------------PFLDGVYFAATEHSNVL------------
--------------------RGWIFG---TSFT----------------NTTQSALFYN-
------------------------------NG--TN---------------------VVI
EVC--------------------------NFNFC--LVP------RVHA---LPNGSSIS
YIYTS-----------------------KANCTYTYVSQSFSLNGAICSSNCDKFKDFRE
-FIFKYSEG-FLHVYSG------------YKAISQGNGFVPSFSALKPFGKF-PIGILVT
N----FSVILTSFYHDSTTTKLAA---------SSLFYGHL------RPITMLLQYDENG
TIYNAIDCSQD-PLSELKCSLKAVNVSKGIYQTSNFRV--TPSQSVA--RYPNITNLC--
PFSQVFNAT--RFPS---VYAWTRERIS--NC-----IADYSVLYNSTSFSTFRCYGVSP
TKLNDLCFSNVYADSM--VVRGDEVRQIA--PSQTGVIADYNYKLPDDFTGCVIAWNSKA
K----------DENGQYF---------YRL--------------FRKSKLLP--------
----FQR-----DVS----N-VTYGSGKN-------------------------------
-------------------------DGCNPSEAD-------CYWPL--------------
------LKYGFT--------SSVSQDYQPYR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-RS------------------TELVYNKCVNFNFNGLTGVGVLTN-SS----KKFL-PFQ
QYGRDNSD--FVNAVRDPPTNAILDITPCSFGGVSVITPGTNLTNEVAVLYQDVNCTDVP
TL-LSLNDYN-VGW----------RVYS--TGTSRFQIQ----AGCLIGAQYQNVTK---
---E--CDIPI----GAGVCASY------------TTKARTSSTPALFAYT-----MSLG
ATQSPAYANNTVLIPTNFSVSVITEVLPVSMAKTAIDCNMYICGDSTECSRLLLQYGSFC
EQLNRALAGV-ALEQDKNTQDVFAQVK--AVYKTP---TFTDF-----------G---G-
-FN-----------------FSS-VLPQ--PGKPSQ---------------RSF--IEDL
LFNKVTLSDAGFM-KEYGNC----LG---DV--AARDLICAQKFNGLTVLPPLLTDEMIA
QYTSSLVGGTIASGWT---AGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFN
NAITQI--------------QSSLTTTSTALSKLQDVINQNANALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSAQTYVTQQLIKAAEVRASANLAATKMSECVL
GQSKRVDFCGK-GFHIMSFPQAAPHGVVFLHMNYIPSSERNFTTVPAICHEG---R----
---------AYF----PREGV----------FI--ND--------NG----NWSITPRNY
YAPSPITTENTFMSGSCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKFFKNH-----TSP
DLDLEDVSKLNASVVDINKEIE--------------KLNNIAQQLNSSLIDLQELGKYEQ
YLKWPWYIWLGFIAGLIAIIMASIMLCCMTSCCSCFKGLCSCGSCCKFDDDSEP------
-----------VLQGVKLHYT----
>Beta06
-----------MLFFLFLQFTLVNS-----------------------------------
QCVNLTGRTPLN---PNYTNS---------------------------------------
--SQRGV-------YYPDT--------------------------IYR------------
--------------------------------S-------DTLVLSQG----YFLPFYS-
-----------------------------NVSWYYSL---------------TANNAATK
RTDNP----------------------IL--DFKDGIYFAATEHSNIV------------
--------------------RGWIFG---TTLD----------------NTSQSLLIVN-
------------------------------NA--TN---------------------VII
KVC--------------------------NFDFC--YDP------YLSGY--YHNNKTWS
IREFAVYSS-------------------YANCTFEYVSKSFMLNISGNGGLFNTLRE---
-FVFRNVDG-HFKIYSK------------FTPVNLNRGLPTGLSVLQPLVEL----PVSI
NITKFRTLLTIHRGDPMPNNGWTA-------FSAAYFVGYL------KPRTFMLKYDENG
TITDAVDCALD-PLSETKCTLKSLTVQKGIYQTSNFRV--QPTQSVV--RFPNITNVC--
PFHNVFNAT--RFPS---VYAWERTKIS--DC-----IADYTVFYNSTSFSTFKCYGVSP
SKLIDLCFTSVYADTF--LIRFSEVRQVA--PGQTGVIADYNYKLPDDFTGCVIAWNTAK
Q-----------DVGNYF---------YRS--------------HRSTKLKP--------
----FER-----DLS----S-DEN------------------------------------
-------------------------GVR----------------TL--------------
------STYDFN--------PNVPLEYQATR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-LS------------------TQLVKNQCVNFNFNGLKGTGVLTD--S----SKRFQSFQ
QFGKDASD--FIDSVRDPQTLEILDITPCSFGGVSVITPGTNTSLEVAVLYQDVNCTDVP
TT-IHADQLT-PAW----------RIYA--TGANVFQTQ----AGCLIGAEHVNASY---
---E--CDIPI----GAGICASY----------HAASILRSTSQKAIVAYT-----MSLG
AENSIAYANNSIAIPTNFSISVTTEVMPVSMAKTSVDCTMYICGDSIECSNLLLQYGSFC
TQLNRALSGI-AIEQDKNTQEVFAQVK--QIYKTP---PIKDF-G---------G-----
-FN-----------------FSQ-ILPD--PS-KPS--------K------RSF--IEDL
LFNKVTLADAGFI-KQYGDC----LG---GV--SARDLICAQKFNGLTVLPPLLTDEMIA
AYTSALVSGTATAGWT---FGIGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFN
SAIGKI--------------QESLTSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGK-GYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHNG---K----
---------AHF----PREGV----------FV--SN--------GT----HWFVTQRNF
YEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQ-PEL-DSFKEELDKYFKNH---TSPDV
DLG--DISGINASVVNIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE------
-PV---------LKGVKLHYT----
>6vsb_B
--------------------AYTNS-----------------------------------
------------------------------------------------------------
--FTRGV-------YYPDK--------------------------VFR------------
--------------------------------S-------SVLHSTQD----LFLPFFS-
----------------------------------------------------NVTW----
-FHNP----------------------VL--PFNDGVYFASTEKSNII------------
--------------------RGWIFG---TTLD----------------SKTQSLLIVN-
------------------------------NA--TN---------------------VVI
KVC--------------------------EFQFC--NDP-------FLSE--FRVYSS--
----------------------------ANNCTFEYVSQPFLKNLRE-------------
-FVFKNIDG-YFKIYSK-------------------HTPPQGFSALEPLVDL-PIGINIT
---RFQTLLAA------------------------YYVGYL------QPRTFLLKYNENG
TITDAVDCALD-PLSETKCTLKSFTVEKGIYQTSNFRV--QPTESIV--RFPNITNLC--
PFGEVFNAT--RFAS---VYAWNRKRIS--NC-----VADYSVLYNSASFSTFKCYGVSP
TKLNDLCFTNVYADSF--VIRGDEVRQIA--PGQTGKIADYNYKLPDDFTGCVIAWNSNN
L-----------DSYNYL---------YRN-------------------LKP--------
----FER-----DIS----T-EIY------------------------------------
--------------------------NC---YFP----------LQ--------------
-------SYGFQ------PT----VGYQPYR------------VVVLSFELL--------
----------------------------------------------HAPATVCGPK----
-KS------------------TNLVKNKCVNFNFNGLTGTGVLTE-SN----KKFL-PFQ
QFGRDIAD--TTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVT
-------------------------------GSNVFQTR----AGCLIGAEHVNNSY---
---E--CDIPI----GAGICAVA--------------------SQSIIAYT-----MSLG
AENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFC
TQLNRALTGI-AVEQDKNTQEVFAQVK--QIYKTP---PIKDF-----------G---G-
-FN-----------------FSQ-ILPD------PS--------K------RSF--IEDL
LFNKVTL----------------------------------QKFNGLTVLPPLLTDEMIA
QYTSALLAGTITSGWT---FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFN
SAIGKI--------------QDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGK-GYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG---K----
---------AHF----PREGV----------FV--SN--------GT----HWFVTQRNF
YEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQ--------------------------P
ELD---------------------------------------------------------
------------------------------------------------------------
-------------------------
>Pangolin
-----------MLFFFFLHFALVNS-----------------------------------
QCVNLTGRAAIQ---PSFTNS---------------------------------------
--SQRGV-------YYPDT--------------------------IFR------------
--------------------------------S-------NTLVLSQG----YFLPFYS-
-----------------------------NVSWYYAL---------------TKTNSAEK
RVDNP----------------------VL--DFKDGIYFAATEKSNIV------------
--------------------RGWIFG---TTLD----------------NTSQSLLIVN-
------------------------------NA--TN---------------------VII
KVC--------------------------NFQFC--YDP------YLSGY--YHNNKTWS
TREFAVYSS-------------------YANCTFEYVSKSFMLDIAGKSGLFDTLRE---
-FVFRNVDG-YFKIYSK------------YTPVNVNSNLPIGFSALEPLVEI-PAGINIT
---KFRTLLTIHRGDPMPNNGWTV-------FSAAYYVGYL------APRTFMLNYNENG
TITDAVDCALD-PLSEAKCTLKSLTVEKGIYQTSNFRV--QPTESIV--RFPNITNLC--
PFGEVFNAT--TFAS---VYAWNRKRIS--NC-----VADYSVLYNSTSFSTFKCYGVSP
TKLNDLCFTNVYADSF--VVRGDEVRQIA--PGQTGRIADYNYKLPDDFTGCVIAWNSNN
L------DSKVGGNYNYL---------YRL--------------FRKSNLKP--------
----FER-----DIS----T-EIYQAGS--------------------------------
-------------------------TPCNGVEGF------NCYFPL--------------
------QSYGFH--------PTNGVGYQPYR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-QS------------------TNLVKNKCVNFNFNGLTGTGVLTE-SS----KKFL-PFQ
QFGRDIAD--TTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVP
VA-IHADQLT-PTW----------RVYS--TGSNVFQTR----AGCLIGAEHVNNTY---
---E--CDIPI----GAGICASY----------QTQTNSRSVSSQAIIAYT-----MSLG
AENSVAYANNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSIECSNLLLQYGSFC
TQLNRALTGI-AVEQDKNTQEVFAQVK--QIYKTP---PIKDF-----------G---G-
-FN-----------------FSQ-ILPD--PSKPSK---------------RSF--IEDL
LFNKVTLADAGFI-KQYGDC----LG---DI--AARDLICAQKFNGLTVLPPLLTDEMIA
QYTSALLAGTITSGWT---FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFN
SAIGKI--------------QDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGK-GYHLMSFPQSAPHGVVFLHVTYVPSQEKNFTTTPAICHEG---K----
---------AHF----PREGV----------FV--SN--------GT----HWFVTQRNF
YEPQIITTDNTFVSGSCDVVIGIVNNTVYDPLQ-PEL-DSFKEELDKYFKNH---TSPDV
DLG--DISGINASVVNIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYIWLGFIAGLIAIIMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE------
-PV-L--------KGVKLHYT----
>WIV16
----------MFIFLFFLTLTSGSD---------------------------------LE
SCTTFDDVQAPN---YPQHSS---------------------------------------
--SRRGV-------YYPDE--------------------------IFR------------
--------------------------------S-------DTLYLTQD----LFLPFYS-
-----------------------------NVTGFHTI---------------NHRF----
--DNP----------------------VI--PFKDGVYFAATEKSNVV------------
--------------------RGWVFG---STMN----------------NKSQSVIIIN-
------------------------------NS--TN---------------------VVI
RAC--------------------------NFELC--DNP------FFAVS--KPTGTQTH
TMIFDN----------------------AFNCTFEYISDSFSLDVAEKSGNFKHLRE---
-FVFKNKDG-FLYVYKG------------YQPIDVVRDLPSGFNILKPIFKL-PLGINIT
---NFRAILTAF---LPAQDTWGT-------SAAAYFVGYL------KPATFMLKYDENG
TITDAVDCSQN-PLAELKCSVKSFEIDKGIYQTSNFRV--APSKEVV--RFPNITNLC--
PFGEVFNAT--TFPS---VYAWERKRIS--NC-----VADYSVLYNSTSFSTFKCYGVSA
TKLNDLCFSNVYADSF--VVKGDDVRQIA--PGQTGVIADYNYKLPDDFTGCVLAWNTRN
I------DATQTGNYNYK---------YRS--------------LRHGKLRP--------
----FER-----DIS----N-VPFSPDG--------------------------------
-------------------------KPCTPPAFN-------CYWPL--------------
------NDYGFY--------ITNGIGYQPYR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-LS------------------TDLIKNQCVNFNFNGLTGTGVLTP--S----SKRFQPFQ
QFGRDVLD--FTDSVRDPKTSEILDISPCSFGGVSVITPGTNTSSEVAVLYQDVNCTDVP
VA-IHADQLT-PSW----------RVYS--TGNNVFQTQ----AGCLIGAEHVDTSY---
---E--CDIPI----GAGICASY----------HTVSSLRSTSQKSIVAYT-----MSLG
ADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFC
TQLNRALSGI-AVEQDRNTREVFAQVK--QMYKTP---TLKDF-G---------G-----
-FN-----------------FSQ-ILPD--PLK-PT--------K------RSF--IEDL
LFNKVTLADAGFM-KQYGEC----LG---DI--NARDLICAQKFNGLTVLPPLLTDDMIA
AYTAALVSGTATAGWT---FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFN
KAISQI--------------QESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGK-GYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEG---K----
---------AYF----PREGV----------FV--FN--------GT----SWFITQRNF
FSPQIITTDNTFVSGSCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKYFKNH---TSPDV
DLG--DISGINASVVNIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSE------
-PV---------LKGVKLHYT----
>Beta09
----------MFIFIITSLSIVLGR---------------------------E-----LD
NCTTFDDVHSPE---YLQYSS---------------------------------------
--SRRGV-------YYPDD--------------------------IFR------------
--------------------------------S-------NVLHLTQD----FFLPFNS-
-----------------------------NVTGFQSI---------------------NY
KFDNP----------------------II--PFRDGIYFAATEKSNVV------------
--------------------RGWAFG---STMN----------------KQSQSVVIIN-
------------------------------NS--TN---------------------VVI
RAC--------------------------NFELC--DNP------FFAVL--KPTMQQIP
SKIFES----------------------ATNCTFEYVSQAFSLDVQENSGNFKHLRE---
-FVFKNKDG-FLYVYKG------------YQSINAVRGLPSGFNTLKPLFKL-PLGINIT
---NFRTILTAY---VPSESVWGT-------AAAAYFVGYL------KPTTFMLSYDENG
TIVDAIDCSEN-PLSELKCTLKNFNVTKGIYQTSNFRV--SPNTEVV--RFPNITNRC--
PFDKVFNAS--RFPS---VYAWERTKIS--DC-----VADYTVLYNSTSFSTFKCYGVSP
SKLIDLCFTSVYADTF--LIRFSEVRQVA--PGETGVIADYNYKLPDDFTGCVIAWNTAK
Q-----------DQGYYY---------YRS--------------HRKTKLKP--------
----FER-----DLS----S-DDN------------------------------------
-------------------------GVR----------------TL--------------
------STYDFN--------QNVPLDYQATR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-LS------------------TQLVKNQCVNFNFNGLKGTGVLTD--S----SKKFQSFQ
QFGRDASD--FTDSVRDPQTLEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVP
TA-IHADQLT-PAW----------RVYS--TGVNVFQTQ----AGCLIGAEHVNASY---
---E--CDIPI----GAGICASY----------HSAATLRSVGQKSIVAYT-----MSLG
AENSIAYANNSIAIPTNFSISVTTEVMPVSMAKTSVDCTMYICGDSQECSNLLLQYGSFC
TQLNRALSGI-AVEQDKNTQEVFAQVK--QIYKTP---AIKDF-G---------G-----
-FN-----------------FSQ-ILPD--PS-KPT--------K------RSF--IEDL
LFNKVTLADAGFM-KQYGEC----LG---DI--SARDLICAQKFNGLTVLPPLLTDEMIA
AYTAALVSGTATAGWT---FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFN
KAISQI--------------QESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGK-GYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEG---K----
---------AYF----PREGV----------FV--SN--------GT----SWFITQRNF
YSPQIITTDNTFVAGNCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKYFKNH---TSPDV
DFG--DISGINASVVNIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYVWLGFIAGLIAIVMATILLCCMTSCCSCLKGACSCGSCCKFDEDDSE------
-PV---------LKGVKLHYT----
>BetaCoronaSC2018
----------MIILLLFLSSATAQE-----------------------------------
GCGVISNKPQRT---FDQYSS---------------------------------------
--TRRGV-------YYNDD--------------------------IFR------------
--------------------------------S-------DVLHLTQD----YFLPFNS-
-----------------------------NVTRYLSL---------------NADQNRLV
YFDNQ----------------------VV--PFLDGIYYAATERSNVI------------
--------------------RGWIFG---STFD----------------NRSQSAIIVN-
------------------------------NS--TH---------------------ILV
KVC--------------------------NFIIC--KEP------MFTVS-----QNRHF
KSWVYQD---------------------ARNCTYDVAYPSFQLDVSLNNNVNFKHLRE--
-FVFKNVDG-FLKVYSS------------YEPINVLNGIPSGFSVLKPVMSL-PLGINIT
---GVRVVMTMF---SSTQQNFLT-------ENAAYYIGYL------KPRTFMLQFNTNG
TIVNAVDCSQD-PLSELKCTLKNFNVTKGIYQTSNFRV--SPTQEVV--RFPNITNRC--
PFDKVFNAS--RFPS---VYAWERIKIS--DC-----VADYTVLYNSTSFSTFKCYGVSP
SKLIDLCFTSVYADTF--LIRSSEVRQVA--PGETGVIADYNYKLPDDFTGCVIAWNTAK
Q-----------DTGSYY---------YRS--------------HRKTKLKP--------
----FER-----DLS----SDDGN------------------------------------
-------------------------GVY----------------TL--------------
------STYDFN--------PNVPVAYQATR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-LS------------------TQLVKNQCVNFNFNGLTGTGVLTP--S----SKRFQPFQ
QFGRDVSD--FTDSVRDPKTSEILDISPCSFGGVSVITPGTNTSSEVAVLYQDVNCTDVP
TA-IRADQLT-PAW----------RIYS--TGLNVFQTQ----AGCLIGAEHVNASY---
---E--CDIPI----GAGICASY----------HTASTLRSTGQKSIVAYT-----MSLG
AENSIAYANNSIAIPTNFSISVTTEVMPVSMSKTSVDCTMYICGDSQECSNLLLQYGSFC
TQLNRALTGI-AIEQDKNTQEVFAQVK--QMYKTP---AIKDF-G---------G-----
-FN-----------------FSQ-ILPD--PS-KPT--------K------RSF--IEDL
LFNKVTLADAGFM-KQYGEC----LG---DI--SARDLICAQKFNGLTVLPPLLTDDMIA
AYTAALVSGTATAGWT---FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFN
KAISQI--------------QESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGR-GYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEG---K----
---------AYF----PREGV----------FV--SN--------GT----SWFITQRNF
YSPQIITTDNTFVAGNCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKYFKNH---TSPDV
DLG--DISGINASVVNIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYVWLGFIAGLIAIVMATILLCCMTSCCSCLKGACSCGSCCKFDEDDSE------
-PV---------LKGVKLHYT----
>Beta03
----------MKIFLFSLLFSAALA---------------------------------QE
GCGSLSFKPQPK---LAQFSS---------------------------------------
--SKRGV-------YYNDD--------------------------IFR------------
--------------------------------S-------DVLHLTQD----YFLPFHS-
-----------------------------NLTQYFSL---------------NVDSDRQV
YFDNP----------------------TL--NFGDGVYFAATEKSNVI------------
--------------------RGWIFG---STMD----------------NSTQSAIIVN-
------------------------------NS--TH---------------------III
RVC--------------------------NFNLC--KEP------MFTVS-----RGVHF
SSWVYQS---------------------AFNCTYDRVEKSFQLDTAPKTGNFKDLRE---
-YVFKNRDG-FLSVYHS------------YTPVDIIRGIPVGFSVLKPILKL-PIGINIT
---SFKVVMTMY---SQTTSNFLS-------ESAAYYVGNL------KYVTFMFQFNENG
TIADAVDCSQN-PLAELKCTLKNFNVSKGIYQTSNFRV--SPSTEVI--RFPNITNRC--
PFDRVFNAS--RFPS---VYAWERTKIS--DC-----VADYTVLYNSTSFSTFKCYGVSP
SKLIDLCFTSVYADTF--LIRFSEVRQIA--PGETGVIADYNYKLPDEFTGCVIAWNTAN
Q-----------DQGQYY---------YRS--------------SRKTKLKP--------
----FER-----DLS----S-DEN------------------------------------
-------------------------GVR----------------TL--------------
------STYDFY--------PSVPLEYQATR------------VVVLSFELL--------
----------------------------------------------NAPATVCGPK----
-LS------------------TSLIKNQCVNFNFNGLKGTGVLTD--S----SKKFQSFQ
QFGRDASD--FTDSVRDPQTLQILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVP
TA-IRADQLT-PAW----------RVYS--AGVNVFQTQ----AGCLIGAEHVNASY---
---E--CDIPI----GAGICASY----------HTASLLRNTGQKSIVAYT-----MSLG
AENSIAYANNSIAIPTNFSISVTTEVMPVSMAKTSVDCTMYICGDSQECSNLLLQYGSFC
TQLNRALSGI-AVEQDKNTQEVFAQVK--QMYKTP---AIKDF-----------G---G-
-FN-----------------FSQ-ILPD--PSKPTK---------------RSF--IEDL
LFNKVTLADAGFM-KQYGEC----LG---DI--SARDLICAQKFNGLTVLPPLLTDEMIA
AYTAALVSGTATAGWT---FGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFN
KAISQI--------------QESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAIS
SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVL
GQSKRVDFCGK-GYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHQG---K----
---------AHF----PREGV----------FV--SN--------GT----SWFITQRNF
FSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQ-PEL-DSFKEELDKYFKNH---TSPDV
DLG--DISGINASVVNIQKEID--------------RLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYVWLGFIAGLIAIVMATILLCCMTSCCSCLKGACSCGSCCKFDEDDSE------
-PV---------LKGVKLHYT----
>Beta07
----------MKIFLFSLLFSAALA---------------------------------QE
GCGSLSYKPQPK---LAQFSS---------------------------------------
--SKRGV-------YYNDD--------------------------IFRS-----------
----------------------------------------DVLHLTRD----YFLPFHS-
-----------------------------NLTQYFSL---------------NVDSDRQV
YFDNP----------------------TL--NFGDGVYFAATEKSNVI------------
--------------------RGWIFG---STMD----------------NSTQSAIIVN-
------------------------------NS--TH---------------------III
RVC--------------------------NFNLC--KEP------MFTVS-----RGVHF
SSWVYQS---------------------AFNCTYDRVENSFQLDTAPKTGNFKDLRE---
-YVFKNHDG-FLSVYHS------------YTPVDIIRGIPVGFSVLKPILKL-PIGINIT