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Not picking up circular DNA correctly #86

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jorainer opened this issue Oct 29, 2018 · 3 comments
Open

Not picking up circular DNA correctly #86

jorainer opened this issue Oct 29, 2018 · 3 comments

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@jorainer
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jorainer commented Oct 29, 2018

Check perl code and ensure circular DNA is correctly identified. See https://support.bioconductor.org/p/114611/ for the original question.

@jorainer
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Reply from Ensembl support:

Dear Rainer,

On 30/10/2018 11:07, Rainer Johannes wrote:
I was puzzled that is_circular on the mitochondrial DNA returns 0. Below is the code I used - eventually there is something wrong with it. I'm using the Perl API version 94 and perl 5, version 18, subversion 0 (v5.18.0).

You are correct, and we're aware of the inconsistency.

So far, we've never put any effort into correcting it in order to better reflect biological reality but we're gonna solve the issue.

Unfortunately, it won't happen straight away as we have to investigate the impact of the change across several species DBs. Likely to happen for the next release.

Hope that helps,

Alessandro

@jorainer
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jorainer commented Nov 5, 2018

We need to check with the next Ensembl release whether it is fixed.

@jorainer
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Still not fixed (see issue #133).

jorainer added a commit that referenced this issue Apr 26, 2022
- `seqinfo,EnsDb`: manually setting `isCircular` to `TRUE` for chromosomes named
  `"MT"` (issue #133, #86).
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