diff --git a/.github/.OwlBot.lock.yaml b/.github/.OwlBot.lock.yaml
index b771c37c..a9fcd07c 100644
--- a/.github/.OwlBot.lock.yaml
+++ b/.github/.OwlBot.lock.yaml
@@ -1,3 +1,3 @@
 docker:
   image: gcr.io/repo-automation-bots/owlbot-python:latest
-  digest: sha256:a1a891041baa4ffbe1a809ac1b8b9b4a71887293c9101c88e8e255943c5aec2d
+  digest: sha256:9743664022bd63a8084be67f144898314c7ca12f0a03e422ac17c733c129d803
diff --git a/noxfile.py b/noxfile.py
index 94ee6a8f..93ea9b14 100644
--- a/noxfile.py
+++ b/noxfile.py
@@ -84,9 +84,15 @@ def default(session):
     constraints_path = str(
         CURRENT_DIRECTORY / "testing" / f"constraints-{session.python}.txt"
     )
-    session.install("asyncmock", "pytest-asyncio", "-c", constraints_path)
-
-    session.install("mock", "pytest", "pytest-cov", "-c", constraints_path)
+    session.install(
+        "mock",
+        "asyncmock",
+        "pytest",
+        "pytest-cov",
+        "pytest-asyncio",
+        "-c",
+        constraints_path,
+    )
 
     session.install("-e", ".", "-c", constraints_path)
 
diff --git a/samples/snippets/hybrid_glossaries/noxfile.py b/samples/snippets/hybrid_glossaries/noxfile.py
index 125bb619..e73436a1 100644
--- a/samples/snippets/hybrid_glossaries/noxfile.py
+++ b/samples/snippets/hybrid_glossaries/noxfile.py
@@ -39,7 +39,7 @@
 
 TEST_CONFIG = {
     # You can opt out from the test for specific Python versions.
-    'ignored_versions': ["2.7"],
+    'ignored_versions': [],
 
     # Old samples are opted out of enforcing Python type hints
     # All new samples should feature them
@@ -88,8 +88,8 @@ def get_pytest_env_vars() -> Dict[str, str]:
 
 
 # DO NOT EDIT - automatically generated.
-# All versions used to tested samples.
-ALL_VERSIONS = ["2.7", "3.6", "3.7", "3.8", "3.9"]
+# All versions used to test samples.
+ALL_VERSIONS = ["3.6", "3.7", "3.8", "3.9"]
 
 # Any default versions that should be ignored.
 IGNORED_VERSIONS = TEST_CONFIG['ignored_versions']
diff --git a/samples/snippets/noxfile.py b/samples/snippets/noxfile.py
index 125bb619..e73436a1 100644
--- a/samples/snippets/noxfile.py
+++ b/samples/snippets/noxfile.py
@@ -39,7 +39,7 @@
 
 TEST_CONFIG = {
     # You can opt out from the test for specific Python versions.
-    'ignored_versions': ["2.7"],
+    'ignored_versions': [],
 
     # Old samples are opted out of enforcing Python type hints
     # All new samples should feature them
@@ -88,8 +88,8 @@ def get_pytest_env_vars() -> Dict[str, str]:
 
 
 # DO NOT EDIT - automatically generated.
-# All versions used to tested samples.
-ALL_VERSIONS = ["2.7", "3.6", "3.7", "3.8", "3.9"]
+# All versions used to test samples.
+ALL_VERSIONS = ["3.6", "3.7", "3.8", "3.9"]
 
 # Any default versions that should be ignored.
 IGNORED_VERSIONS = TEST_CONFIG['ignored_versions']
diff --git a/scripts/readme-gen/templates/install_deps.tmpl.rst b/scripts/readme-gen/templates/install_deps.tmpl.rst
index a0406dba..275d6498 100644
--- a/scripts/readme-gen/templates/install_deps.tmpl.rst
+++ b/scripts/readme-gen/templates/install_deps.tmpl.rst
@@ -12,7 +12,7 @@ Install Dependencies
    .. _Python Development Environment Setup Guide:
        https://cloud.google.com/python/setup
 
-#. Create a virtualenv. Samples are compatible with Python 2.7 and 3.4+.
+#. Create a virtualenv. Samples are compatible with Python 3.6+.
 
     .. code-block:: bash