diff --git a/.kokoro/presubmit/prerelease-deps-3.8.cfg b/.kokoro/presubmit/prerelease-deps-3.8.cfg
index f06806baf..fabe3e347 100644
--- a/.kokoro/presubmit/prerelease-deps-3.8.cfg
+++ b/.kokoro/presubmit/prerelease-deps-3.8.cfg
@@ -3,5 +3,5 @@
 # Only run this nox session.
 env_vars: {
     key: "NOX_SESSION"
-    value: "prerelease_deps"
-}
\ No newline at end of file
+    value: "prerelease_deps-3.8"
+}
diff --git a/.kokoro/presubmit/snippets-3.10.cfg b/.kokoro/presubmit/snippets-3.10.cfg
new file mode 100644
index 000000000..dde182fb9
--- /dev/null
+++ b/.kokoro/presubmit/snippets-3.10.cfg
@@ -0,0 +1,7 @@
+# Format: //devtools/kokoro/config/proto/build.proto
+
+# Only run this nox session.
+env_vars: {
+    key: "NOX_SESSION"
+    value: "snippets-3.10"
+}
diff --git a/.kokoro/presubmit/snippets-2.7.cfg b/.kokoro/presubmit/system-3.10.cfg
similarity index 82%
rename from .kokoro/presubmit/snippets-2.7.cfg
rename to .kokoro/presubmit/system-3.10.cfg
index 3bd6134d2..30956a3ab 100644
--- a/.kokoro/presubmit/snippets-2.7.cfg
+++ b/.kokoro/presubmit/system-3.10.cfg
@@ -3,5 +3,5 @@
 # Only run this nox session.
 env_vars: {
     key: "NOX_SESSION"
-    value: "snippets-2.7"
+    value: "system-3.10"
 }
diff --git a/noxfile.py b/noxfile.py
index 64eacaff5..6f04940c9 100644
--- a/noxfile.py
+++ b/noxfile.py
@@ -27,8 +27,8 @@
 BLACK_PATHS = ("docs", "google", "samples", "tests", "noxfile.py", "setup.py")
 
 DEFAULT_PYTHON_VERSION = "3.8"
-SYSTEM_TEST_PYTHON_VERSIONS = ["3.8"]
-UNIT_TEST_PYTHON_VERSIONS = ["3.6", "3.7", "3.8", "3.9"]
+SYSTEM_TEST_PYTHON_VERSIONS = ["3.8", "3.10"]
+UNIT_TEST_PYTHON_VERSIONS = ["3.6", "3.7", "3.8", "3.9", "3.10"]
 CURRENT_DIRECTORY = pathlib.Path(__file__).parent.absolute()
 
 # 'docfx' is excluded since it only needs to run in 'docs-presubmit'
@@ -69,7 +69,12 @@ def default(session, install_extras=True):
         constraints_path,
     )
 
-    install_target = ".[all]" if install_extras else "."
+    if install_extras and session.python == "3.10":
+        install_target = ".[bqstorage,pandas,tqdm,opentelemetry]"
+    elif install_extras:
+        install_target = ".[all]"
+    else:
+        install_target = "."
     session.install("-e", install_target, "-c", constraints_path)
 
     session.install("ipython", "-c", constraints_path)
@@ -153,7 +158,11 @@ def system(session):
     # Data Catalog needed for the column ACL test with a real Policy Tag.
     session.install("google-cloud-datacatalog", "-c", constraints_path)
 
-    session.install("-e", ".[all]", "-c", constraints_path)
+    if session.python == "3.10":
+        extras = "[bqstorage,pandas,tqdm,opentelemetry]"
+    else:
+        extras = "[all]"
+    session.install("-e", f".{extras}", "-c", constraints_path)
     session.install("ipython", "-c", constraints_path)
 
     # Run py.test against the system tests.
diff --git a/samples/geography/noxfile_config.py b/samples/geography/noxfile_config.py
index 7d2e02346..315bd5be8 100644
--- a/samples/geography/noxfile_config.py
+++ b/samples/geography/noxfile_config.py
@@ -22,7 +22,12 @@
 
 TEST_CONFIG_OVERRIDE = {
     # You can opt out from the test for specific Python versions.
-    "ignored_versions": ["2.7"],
+    "ignored_versions": [
+        "2.7",
+        # TODO: Enable 3.10 once there is a geopandas/fiona release.
+        # https://github.com/Toblerity/Fiona/issues/1043
+        "3.10",
+    ],
     # An envvar key for determining the project id to use. Change it
     # to 'BUILD_SPECIFIC_GCLOUD_PROJECT' if you want to opt in using a
     # build specific Cloud project. You can also use your own string
diff --git a/samples/geography/requirements.txt b/samples/geography/requirements.txt
index ecd428ab9..e2de86673 100644
--- a/samples/geography/requirements.txt
+++ b/samples/geography/requirements.txt
@@ -24,14 +24,12 @@ importlib-metadata==4.8.1
 libcst==0.3.21
 munch==2.5.0
 mypy-extensions==0.4.3
-numpy==1.19.5; python_version < "3.7"
-numpy==1.21.2; python_version > "3.6"
 packaging==21.0
 pandas==1.1.5; python_version < '3.7'
-pandas==1.3.2; python_version >= '3.7'
+pandas==1.3.4; python_version >= '3.7'
 proto-plus==1.19.2
 protobuf==3.18.0
-pyarrow==5.0.0
+pyarrow==6.0.0
 pyasn1==0.4.8
 pyasn1-modules==0.2.8
 pycparser==2.20
@@ -43,7 +41,7 @@ pytz==2021.1
 PyYAML==5.4.1
 requests==2.26.0
 rsa==4.7.2
-Shapely==1.7.1
+Shapely==1.8.0
 six==1.16.0
 typing-extensions==3.10.0.2
 typing-inspect==0.7.1
diff --git a/samples/magics/requirements.txt b/samples/magics/requirements.txt
index f9b9d023c..5cc7ec33f 100644
--- a/samples/magics/requirements.txt
+++ b/samples/magics/requirements.txt
@@ -1,12 +1,11 @@
-google-cloud-bigquery==2.27.1
 google-cloud-bigquery-storage==2.9.0
 google-auth-oauthlib==0.4.6
 grpcio==1.41.0
 ipython==7.16.1; python_version < '3.7'
-ipython==7.17.0; python_version >= '3.7'
+ipython==7.29.0; python_version >= '3.7'
 matplotlib==3.3.4; python_version < '3.7'
-matplotlib==3.4.1; python_version >= '3.7'
+matplotlib==3.5.0rc1; python_version >= '3.7'
 pandas==1.1.5; python_version < '3.7'
-pandas==1.3.2; python_version >= '3.7'
-pyarrow==5.0.0
+pandas==1.3.4; python_version >= '3.7'
+pyarrow==6.0.0
 pytz==2021.1
diff --git a/samples/snippets/requirements.txt b/samples/snippets/requirements.txt
index f9b9d023c..f79552392 100644
--- a/samples/snippets/requirements.txt
+++ b/samples/snippets/requirements.txt
@@ -1,12 +1,11 @@
-google-cloud-bigquery==2.27.1
 google-cloud-bigquery-storage==2.9.0
 google-auth-oauthlib==0.4.6
 grpcio==1.41.0
 ipython==7.16.1; python_version < '3.7'
-ipython==7.17.0; python_version >= '3.7'
+ipython==7.29.0; python_version >= '3.7'
 matplotlib==3.3.4; python_version < '3.7'
 matplotlib==3.4.1; python_version >= '3.7'
 pandas==1.1.5; python_version < '3.7'
-pandas==1.3.2; python_version >= '3.7'
-pyarrow==5.0.0
+pandas==1.3.4; python_version >= '3.7'
+pyarrow==6.0.0
 pytz==2021.1
diff --git a/setup.py b/setup.py
index 95dad190a..db69c45b1 100644
--- a/setup.py
+++ b/setup.py
@@ -59,7 +59,7 @@
     ]
     + pyarrow_dep,
     "geopandas": ["geopandas>=0.9.0, <1.0dev", "Shapely>=1.6.0, <2.0dev"],
-    "pandas": ["pandas>=0.23.0"] + pyarrow_dep,
+    "pandas": ["pandas>=0.24.2"] + pyarrow_dep,
     "bignumeric_type": pyarrow_dep,
     "tqdm": ["tqdm >= 4.7.4, <5.0.0dev"],
     "opentelemetry": [
@@ -127,6 +127,7 @@
         "Programming Language :: Python :: 3.7",
         "Programming Language :: Python :: 3.8",
         "Programming Language :: Python :: 3.9",
+        "Programming Language :: Python :: 3.10",
         "Operating System :: OS Independent",
         "Topic :: Internet",
     ],
@@ -135,7 +136,7 @@
     namespace_packages=namespaces,
     install_requires=dependencies,
     extras_require=extras,
-    python_requires=">=3.6, <3.10",
+    python_requires=">=3.6, <3.11",
     include_package_data=True,
     zip_safe=False,
 )