diff --git a/sqlalchemy_bigquery/base.py b/sqlalchemy_bigquery/base.py
index 12ab3e36..d1b0a75b 100644
--- a/sqlalchemy_bigquery/base.py
+++ b/sqlalchemy_bigquery/base.py
@@ -247,7 +247,12 @@ def visit_insert(self, insert_stmt, asfrom=False, **kw):
         )
 
     def visit_column(
-        self, column, add_to_result_map=None, include_table=True, **kwargs
+        self,
+        column,
+        add_to_result_map=None,
+        include_table=True,
+        result_map_targets=(),
+        **kwargs,
     ):
         name = orig_name = column.name
         if name is None:
@@ -258,7 +263,12 @@ def visit_column(
             name = self._truncated_identifier("colident", name)
 
         if add_to_result_map is not None:
-            add_to_result_map(name, orig_name, (column, name, column.key), column.type)
+            targets = (column, name, column.key) + result_map_targets
+            if getattr(column, "_tq_label", None):
+                # _tq_label was added in SQLAlchemy 1.4
+                targets += (column._tq_label,)
+
+            add_to_result_map(name, orig_name, targets, column.type)
 
         if is_literal:
             name = self.escape_literal_column(name)
@@ -271,6 +281,7 @@ def visit_column(
             tablename = table.name
             if isinstance(tablename, elements._truncated_label):
                 tablename = self._truncated_identifier("alias", tablename)
+
             return self.preparer.quote(tablename) + "." + name
 
     def visit_label(self, *args, within_group_by=False, **kwargs):
diff --git a/tests/system/conftest.py b/tests/system/conftest.py
index 077f06a8..d9db14ab 100644
--- a/tests/system/conftest.py
+++ b/tests/system/conftest.py
@@ -21,6 +21,7 @@
 from typing import List
 
 import pytest
+import sqlalchemy
 
 from google.cloud import bigquery
 import test_utils.prefixer
@@ -137,3 +138,8 @@ def cleanup_datasets(bigquery_client: bigquery.Client):
             bigquery_client.delete_dataset(
                 dataset, delete_contents=True, not_found_ok=True
             )
+
+
+@pytest.fixture
+def metadata():
+    return sqlalchemy.MetaData()
diff --git a/tests/system/test_sqlalchemy_bigquery.py b/tests/system/test_sqlalchemy_bigquery.py
index 4380b0be..1390d11c 100644
--- a/tests/system/test_sqlalchemy_bigquery.py
+++ b/tests/system/test_sqlalchemy_bigquery.py
@@ -691,3 +691,37 @@ def test_has_table(engine, engine_using_test_dataset, bigquery_dataset):
     assert engine_using_test_dataset.has_table(f"{bigquery_dataset}.sample") is True
 
     assert engine_using_test_dataset.has_table("sample_alt") is False
+
+
+def test_distinct_188(engine, bigquery_dataset):
+    from sqlalchemy.ext.declarative import declarative_base
+    from sqlalchemy import Column, Integer
+    from sqlalchemy.orm import sessionmaker
+
+    Base = declarative_base()
+
+    class MyTable(Base):
+        __tablename__ = f"{bigquery_dataset}.test_distinct_188"
+        id = Column(Integer, primary_key=True)
+        my_column = Column(Integer)
+
+    MyTable.__table__.create(engine)
+
+    Session = sessionmaker(bind=engine)
+    db = Session()
+    db.add_all([MyTable(id=i, my_column=i % 2) for i in range(9)])
+    db.commit()
+
+    expected = [(0,), (1,)]
+
+    assert sorted(db.query(MyTable.my_column).distinct().all()) == expected
+    assert (
+        sorted(
+            db.query(
+                sqlalchemy.distinct(MyTable.my_column).label("just_a_random_label")
+            ).all()
+        )
+        == expected
+    )
+
+    assert sorted(db.query(sqlalchemy.distinct(MyTable.my_column)).all()) == expected