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Replace URS ID for human ncRNAs with symbol #854

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hattrill opened this issue Dec 6, 2023 · 8 comments
Open

Replace URS ID for human ncRNAs with symbol #854

hattrill opened this issue Dec 6, 2023 · 8 comments

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@hattrill
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hattrill commented Dec 6, 2023

When using RNAcentral IDs for human ncRNAs, the URS is displayed in Noctua/Alliance pathway view. Could this be replaced with the symbol?

e.g. http://noctua.geneontology.org/workbench/noctua-visual-pathway-editor/?model_id=gomodel%3A654d809000000802

for the above example URS000012F9EC_9606 (https://rnacentral.org/rna/URS000012F9EC/9606) is displayed, but would like to see hsa-miR-4691-3p

@pgaudet
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pgaudet commented Dec 6, 2023

@balhoff Is this a NEO issue?

@balhoff
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balhoff commented Dec 6, 2023

@pgaudet yes I think so; the actual label value in NEO is 'URS000012F9EC_9606 Hsap'.

@pgaudet
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pgaudet commented Dec 7, 2023

what does the raw data look like? Is is possible to use the gene name? 'hsa-miR-4691-3p' ?

@balhoff
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balhoff commented Dec 7, 2023

The cells in that row (and all the rows) of the GPI look like this:

1. RNAcentral
2. URS000012F9EC_9606	
3.	
4. Homo sapiens (human) hsa-miR-4691-3p	
5.	
6. miRNA
7. taxon:9606		
8. 	
9.
10.

So maybe they should be putting something in column 3 (DB_Object_Symbol)?

@vanaukenk
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@balhoff @pgaudet @hattrill

Yes, RNACentral would need to populate column 3 with the symbol in order for that to be shown in the GO-CAM models.

Also tagging @blakesweeney here to see if RNACentral could update the gpi file GO retrieves. See:
https://github.com/geneontology/go-site/blob/master/metadata/datasets/rnacentral.yaml

@blakesweeney
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Hi, that sounds like a reasonable change for us to make. If there is no rush for it I will schedule it for our next release in 3 months. If there we can do something more quickly once people are back from holidays. Let me know what is preferred.

@vanaukenk
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vanaukenk commented Dec 8, 2023

Thank you @blakesweeney

@hattrill
Do you have a specific time frame in mind for this, i.e. do you need this for a figure in the ncRNA paper?

@hattrill
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@vanaukenk No rush for me. Thanks

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