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PTN001115588 #5232

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rozaru opened this issue May 13, 2024 · 3 comments
Closed

PTN001115588 #5232

rozaru opened this issue May 13, 2024 · 3 comments
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@rozaru
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rozaru commented May 13, 2024

  • PTHR ID & PTN node:
    PTN001115588
  • Sequences with problematic annotation (ID + gene/protein name):
    D. melanogaster
    Chs2 (Q9VNW7)
    kkv (Q8IPN4)
  • Type of Issue: Erroneous source or erroneous propagation, or other issue
    erroneous propagation

In D. melanogaster and likely in other insects, chitin (the product of chitin synthase) is find in the cuticle and peritrophic matrice and is not part of cell wall.
According to the GO definition, cell wall is mainly found in yeast and plants.
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.

  • Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).
@marcfeuermann
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BPs were well annotated but I indeed had to corrects CCs,

@rozaru rozaru reopened this May 23, 2024
@rozaru
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rozaru commented May 23, 2024

@marcfeuermann
Could also the cell septum term be removed for D. melanogaster Chs2 (Q9VNW7) and kkv (Q8IPN4) and arthropods in general as this term described a structure that is likely found only in Bacteria and Fungi.
I wasn't sure if this was included in the "had to corrects CCs" in your comment.
Thanks

@marcfeuermann
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marcfeuermann commented May 28, 2024

This has of course also been corrected.

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