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IPR002225 3-beta-hydroxy-delta5-steroid dehydrogenase activity #5215

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ValWood opened this issue Apr 29, 2024 · 1 comment
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IPR002225 3-beta-hydroxy-delta5-steroid dehydrogenase activity #5215

ValWood opened this issue Apr 29, 2024 · 1 comment
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@ValWood
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ValWood commented Apr 29, 2024

  • InterPro ID / label

HI,
could you have a look at this mapping and see where it comes from? I could not detect a source annotation (at least in eukaryotes), and it isn't a parent of any of the more specific annotations
GO:0003854
3-beta-hydroxy-delta5-steroid dehydrogenase activity
(http://www.ebi.ac.uk/interpro/entry/IPR002225)

https://www.pombase.org/gene/SPBC3F6.02c

  • Example sequences with problematic annotation (ID + gene/protein name):

  • Description of issue

@blazaropinto
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Hi Val,

Thank you very much for that. This term is mapped to human P14060 (PMID:1401999) or C.elegans Q9XWF0 (PMID:18495818), but shouldn't propagate to all proteins in this entry. This entry already has the more general MF GO:0016616, so I'll just remove GO:0003854. The changes will be available in InterPro 100.0.

Best,
Beatriz

@ValWood ValWood changed the title IPR002225 IPR002225 3-beta-hydroxy-delta5-steroid dehydrogenase activity May 2, 2024
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