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Incorrect Unirule mapping: UR000376192 #5211

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ValWood opened this issue Apr 29, 2024 · 4 comments
Open

Incorrect Unirule mapping: UR000376192 #5211

ValWood opened this issue Apr 29, 2024 · 4 comments
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@ValWood
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ValWood commented Apr 29, 2024

UniProt UniRule (ID and label):

UR000376192

Sequences with problematic annotation (ID + gene/protein name):

mapping https://www.pombase.org/gene/SPBC337.15c (coq7)

Description of issue

Coq7 is 3-demethoxyubiquinol 3-hydroxylase activity (GO:0008682) (a monoxygenase)
https://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0008682

I can't see any evidence that coq7 is multifunctional, therefore

I'm not sure
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
IEA with UR000376192

is correct ?

@ValWood
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ValWood commented Apr 29, 2024

Actually, @pgaudet this could be a missing parent?

I realise I assigned incorrectly, reassigning to ivo

@ValWood
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ValWood commented Apr 29, 2024

Actually it is UNiRule, not sure who does these...

@ValWood
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ValWood commented Apr 29, 2024

there does not seem to be any NAD(P)H https://www.pombase.org/term/GO:0008682
so I'll go ahead and filter for now.

@pedruzzi
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Actually it is UNiRule, not sure who does these...

It's a HAMAP, so that would be me. I'll have a look.

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