diff --git a/packages/react-dom/src/client/ReactDOMFiberComponent.js b/packages/react-dom/src/client/ReactDOMFiberComponent.js
index fd3d0b4f0ad97..866528c100842 100644
--- a/packages/react-dom/src/client/ReactDOMFiberComponent.js
+++ b/packages/react-dom/src/client/ReactDOMFiberComponent.js
@@ -390,7 +390,7 @@ export function createElement(
       // `select` elements automatically pick the first item.
       // See https://github.com/facebook/react/issues/13222
       if (type === 'select' && props.multiple) {
-        domElement.setAttribute('multiple', 'true');
+        domElement.multiple = true;
       }
     }
   } else {