enhanced visualization considering hierarchical nature of enrichment terms

[sreichl]

• use this package for simplifying results AND word clouds next to heatmaps!
  • http://www.bioconductor.org/packages/release/bioc/html/simplifyEnrichment.html
  • uses complexHeatmap
• traverse up the GO hierarchy and find most common parent node as systematic high level annotation of multiple GO terms
• implement pathway-based visualization
  • “old” for mapping results on a (KEGG) pathway: pathview https://pathview.r-forge.r-project.org/
  • "new” Systems Biology Graphical Notation includes many more pathway sources, plus vector graphics. SBGNview https://www.bioconductor.org/packages/release/bioc/html/SBGNview.html

[sreichl]

not generally applicable across results, and requires customization. put in docs for downstream analysis.