notebooks/dataprep/01a-UniProtProtein.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# UniProt Viral and Host Protein Data\n",
    "**[Work in progress]**\n",
    "\n",
    "This notebook downloads and standardizes viral and host protein data from UniProt for ingestion into the Knowledge Graph.\n",
    "\n",
    "Data source: [UniProt](https://www.uniprot.org/)\n",
    "\n",
    "Authors: Peter Rose (pwrose@ucsd.edu)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "import os\n",
    "import re\n",
    "import hashlib \n",
    "import urllib\n",
    "import pandas as pd\n",
    "import numpy as np\n",
    "from pathlib import Path"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "pd.options.display.max_rows = None  # display all rows\n",
    "pd.options.display.max_columns = None  # display all columns"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "/Users/peter/Library/Application Support/com.Neo4j.Relate/data/dbmss/dbms-8bf637fc-0d20-4d9f-9c6f-f7e72e92a4da/import\n"
     ]
    }
   ],
   "source": [
    "NEO4J_IMPORT = Path(os.getenv('NEO4J_IMPORT'))\n",
    "print(NEO4J_IMPORT)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Get list of organisms in the Knowledge Graph"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {},
   "outputs": [],
   "source": [
    "organisms = pd.read_csv(\"../../reference_data/Organism.csv\", dtype=str)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [],
   "source": [
    "# exclude organisms without an NCBI taxonomy id\n",
    "organisms = organisms[organisms['id'].str.startswith('taxonomy')]\n",
    "# remove CURIE\n",
    "organisms['taxonomy'] = organisms['id'].apply(lambda x: x.split(':')[1])\n",
    "taxonomy_ids = organisms['taxonomy'].unique()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Download data from UniProt"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {},
   "outputs": [],
   "source": [
    "columns = 'id,entry%20name,p,sequence,length,protein%20names,reviewed,organism-id,feature(CHAIN),feature(PEPTIDE),go(biological%20process)'"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Downloaded 18413 proteins for taxonomy id 2697049\n",
      "Downloaded 10 proteins for taxonomy id 1263720\n",
      "Downloaded 96 proteins for taxonomy id 694009\n",
      "Downloaded 9 proteins for taxonomy id 443239\n",
      "Downloaded 1578 proteins for taxonomy id 31631\n",
      "Downloaded 455 proteins for taxonomy id 11137\n",
      "Downloaded 985 proteins for taxonomy id 277944\n",
      "Downloaded 14 proteins for taxonomy id 12131\n",
      "Downloaded 16 proteins for taxonomy id 12134\n",
      "Downloaded 10 proteins for taxonomy id 766791\n",
      "Downloaded 146 proteins for taxonomy id 693998\n",
      "Downloaded 15 proteins for taxonomy id 1487703\n",
      "Downloaded 12 proteins for taxonomy id 285949\n",
      "Downloaded 194237 proteins for taxonomy id 9606\n",
      "Downloaded 86618 proteins for taxonomy id 10090\n",
      "Downloaded 144 proteins for taxonomy id 59477\n",
      "Downloaded 22 proteins for taxonomy id 608659\n",
      "Downloaded 0 proteins for taxonomy id 49442\n",
      "Downloaded 80 proteins for taxonomy id 9974\n",
      "Downloaded 187 proteins for taxonomy id 143292\n",
      "Downloaded 0 proteins for taxonomy id 71116\n",
      "Downloaded 0 proteins for taxonomy id 9608\n",
      "Downloaded 41789 proteins for taxonomy id 9685\n",
      "Downloaded 54 proteins for taxonomy id 9666\n",
      "Downloaded 5 proteins for taxonomy id 419130\n",
      "Downloaded 16339 proteins for taxonomy id 452646\n",
      "Downloaded 32225 proteins for taxonomy id 10036\n",
      "Downloaded 249 proteins for taxonomy id 9689\n",
      "Downloaded 223 proteins for taxonomy id 9694\n"
     ]
    }
   ],
   "source": [
    "dfs = list()\n",
    "for taxon in taxonomy_ids:\n",
    "    url = f'https://www.uniprot.org/uniprot/?query=organism:{taxon}&columns={columns}&format=tab'\n",
    "    try:\n",
    "        df = pd.read_csv(url, sep='\\t', dtype='str')\n",
    "        if df.shape[0] > 0:\n",
    "            print(f'Downloaded {df.shape[0]} proteins for taxonomy id {taxon}')\n",
    "            dfs.append(df)\n",
    "        else:\n",
    "            print(f'Downloaded 0 proteins for taxonomy id {taxon}')\n",
    "    except:\n",
    "        print(f'Downloaded 0 proteins for taxonomy id {taxon}')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp = pd.concat(dfs)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp.reset_index(drop=True,inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "(393931, 10)\n"
     ]
    }
   ],
   "source": [
    "unp.fillna('', inplace=True)\n",
    "print(unp.shape)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Entry</th>\n",
       "      <th>Entry name</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>Length</th>\n",
       "      <th>Protein names</th>\n",
       "      <th>Status</th>\n",
       "      <th>Organism ID</th>\n",
       "      <th>Chain</th>\n",
       "      <th>Peptide</th>\n",
       "      <th>Gene ontology (biological process)</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>393926</th>\n",
       "      <td>A0A0A0Y6P1</td>\n",
       "      <td>A0A0A0Y6P1_PANTI</td>\n",
       "      <td>MSYRDLIVGIIFLSQTVVGIVGNFSLLYHYLFLYHTECRVRSTHLI...</td>\n",
       "      <td>314</td>\n",
       "      <td>Vomeronasal type-1 receptor</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>9694</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>response to pheromone [GO:0019236]</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>393927</th>\n",
       "      <td>K7NVN4</td>\n",
       "      <td>K7NVN4_PANTI</td>\n",
       "      <td>FKYLLMFLITMMILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRAD...</td>\n",
       "      <td>159</td>\n",
       "      <td>NADH:ubiquinone reductase (H(+)-translocating)...</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>9694</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>393928</th>\n",
       "      <td>B6E5W4</td>\n",
       "      <td>B6E5W4_PANTI</td>\n",
       "      <td>LLGKTECHFTNGTELVRFLDRYFYNGEEYVRFDSDVGEYRAVTELG...</td>\n",
       "      <td>79</td>\n",
       "      <td>MHC class II antigen (Fragment)</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>9694</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>antigen processing and presentation [GO:001988...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>393929</th>\n",
       "      <td>H9L6P9</td>\n",
       "      <td>H9L6P9_PANTI</td>\n",
       "      <td>RLHQRGHDVVVIAPEASVYIKEGAFYTLKSYPVPFRREDVEASFTG...</td>\n",
       "      <td>213</td>\n",
       "      <td>UDP-glucuronosyltransferase 1A1 (Fragment)</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>9694</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>393930</th>\n",
       "      <td>Q5MLT9</td>\n",
       "      <td>Q5MLT9_PANTI</td>\n",
       "      <td>ILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYN...</td>\n",
       "      <td>163</td>\n",
       "      <td>NADH:ubiquinone reductase (H(+)-translocating)...</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>9694</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "             Entry        Entry name  \\\n",
       "393926  A0A0A0Y6P1  A0A0A0Y6P1_PANTI   \n",
       "393927      K7NVN4      K7NVN4_PANTI   \n",
       "393928      B6E5W4      B6E5W4_PANTI   \n",
       "393929      H9L6P9      H9L6P9_PANTI   \n",
       "393930      Q5MLT9      Q5MLT9_PANTI   \n",
       "\n",
       "                                                 Sequence Length  \\\n",
       "393926  MSYRDLIVGIIFLSQTVVGIVGNFSLLYHYLFLYHTECRVRSTHLI...    314   \n",
       "393927  FKYLLMFLITMMILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRAD...    159   \n",
       "393928  LLGKTECHFTNGTELVRFLDRYFYNGEEYVRFDSDVGEYRAVTELG...     79   \n",
       "393929  RLHQRGHDVVVIAPEASVYIKEGAFYTLKSYPVPFRREDVEASFTG...    213   \n",
       "393930  ILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYN...    163   \n",
       "\n",
       "                                            Protein names      Status  \\\n",
       "393926                        Vomeronasal type-1 receptor  unreviewed   \n",
       "393927  NADH:ubiquinone reductase (H(+)-translocating)...  unreviewed   \n",
       "393928                    MHC class II antigen (Fragment)  unreviewed   \n",
       "393929         UDP-glucuronosyltransferase 1A1 (Fragment)  unreviewed   \n",
       "393930  NADH:ubiquinone reductase (H(+)-translocating)...  unreviewed   \n",
       "\n",
       "       Organism ID Chain Peptide  \\\n",
       "393926        9694                 \n",
       "393927        9694                 \n",
       "393928        9694                 \n",
       "393929        9694                 \n",
       "393930        9694                 \n",
       "\n",
       "                       Gene ontology (biological process)  \n",
       "393926                 response to pheromone [GO:0019236]  \n",
       "393927                                                     \n",
       "393928  antigen processing and presentation [GO:001988...  \n",
       "393929                                                     \n",
       "393930                                                     "
      ]
     },
     "execution_count": 11,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.tail()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['reviewed'] = unp['Status'].apply(lambda s: 'True' if s == 'reviewed' else 'False')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Format synonymes"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array([\"Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']\"],\n",
       "      dtype=object)"
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.query(\"Entry == 'P0DTC2'\")['Protein names'].values"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Remove terms in brackets, e.g., [Cleaved into: ...]\n",
    "\n",
    "[\"Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['synonymes'] = unp['Protein names'].str.replace(\"\\\\[.+\\\\]\", \"\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array(['Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) '],\n",
       "      dtype=object)"
      ]
     },
     "execution_count": 15,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.query(\"Entry == 'P0DTC2'\")['synonymes'].values"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Convert synonymes to a semicolon separated list to represent these one to many relationships in a CSV file."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['synonymes'] = unp['synonymes'].str.replace('(', ';')\n",
    "unp['synonymes'] = unp['synonymes'].str.replace(' ;', ';')\n",
    "unp['synonymes'] = unp['synonymes'].str.replace(')', '')\n",
    "unp['synonymes'] = unp['synonymes'].str.strip()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array(['Spike glycoprotein;S glycoprotein;E2;Peplomer protein'],\n",
       "      dtype=object)"
      ]
     },
     "execution_count": 17,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.query(\"Entry == 'P0DTC2'\")['synonymes'].values"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Entry</th>\n",
       "      <th>Entry name</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>Length</th>\n",
       "      <th>Protein names</th>\n",
       "      <th>Status</th>\n",
       "      <th>Organism ID</th>\n",
       "      <th>Chain</th>\n",
       "      <th>Peptide</th>\n",
       "      <th>Gene ontology (biological process)</th>\n",
       "      <th>reviewed</th>\n",
       "      <th>synonymes</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>P0DTC5</td>\n",
       "      <td>VME1_SARS2</td>\n",
       "      <td>MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein (M) (E1 glycoprotein) (Matrix...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..222;  /note=\"Membrane protein\";  /id=...</td>\n",
       "      <td></td>\n",
       "      <td>mitigation of host immune response by virus [G...</td>\n",
       "      <td>True</td>\n",
       "      <td>Membrane protein;M;E1 glycoprotein;Matrix glyc...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>P0DTD3</td>\n",
       "      <td>Y14_SARS2</td>\n",
       "      <td>MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...</td>\n",
       "      <td>73</td>\n",
       "      <td>Uncharacterized protein 14 (ORF14)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..73;  /note=\"Uncharacterized protein 1...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>Uncharacterized protein 14;ORF14</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>P0DTC4</td>\n",
       "      <td>VEMP_SARS2</td>\n",
       "      <td>MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein (E) (sM protein)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..75;  /note=\"Envelope small membrane p...</td>\n",
       "      <td></td>\n",
       "      <td>pore formation by virus in membrane of host ce...</td>\n",
       "      <td>True</td>\n",
       "      <td>Envelope small membrane protein;E;sM protein</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "    Entry   Entry name                                           Sequence  \\\n",
       "0  P0DTC5   VME1_SARS2  MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...   \n",
       "1  P0DTC1    R1A_SARS2  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   \n",
       "2  P0DTD3    Y14_SARS2  MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...   \n",
       "3  P0DTC4   VEMP_SARS2  MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...   \n",
       "4  P0DTC2  SPIKE_SARS2  MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   \n",
       "\n",
       "  Length                                      Protein names    Status  \\\n",
       "0    222  Membrane protein (M) (E1 glycoprotein) (Matrix...  reviewed   \n",
       "1   4405  Replicase polyprotein 1a (pp1a) (ORF1a polypro...  reviewed   \n",
       "2     73                 Uncharacterized protein 14 (ORF14)  reviewed   \n",
       "3     75   Envelope small membrane protein (E) (sM protein)  reviewed   \n",
       "4   1273  Spike glycoprotein (S glycoprotein) (E2) (Pepl...  reviewed   \n",
       "\n",
       "  Organism ID                                              Chain Peptide  \\\n",
       "0     2697049  CHAIN 1..222;  /note=\"Membrane protein\";  /id=...           \n",
       "1     2697049  CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "2     2697049  CHAIN 1..73;  /note=\"Uncharacterized protein 1...           \n",
       "3     2697049  CHAIN 1..75;  /note=\"Envelope small membrane p...           \n",
       "4     2697049  CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "\n",
       "                  Gene ontology (biological process) reviewed  \\\n",
       "0  mitigation of host immune response by virus [G...     True   \n",
       "1  induction by virus of catabolism of host mRNA ...     True   \n",
       "2                                                        True   \n",
       "3  pore formation by virus in membrane of host ce...     True   \n",
       "4  endocytosis involved in viral entry into host ...     True   \n",
       "\n",
       "                                           synonymes  \n",
       "0  Membrane protein;M;E1 glycoprotein;Matrix glyc...  \n",
       "1    Replicase polyprotein 1a;pp1a;ORF1a polyprotein  \n",
       "2                   Uncharacterized protein 14;ORF14  \n",
       "3       Envelope small membrane protein;E;sM protein  \n",
       "4  Spike glycoprotein;S glycoprotein;E2;Peplomer ...  "
      ]
     },
     "execution_count": 18,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array(['CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO_0000006685\"; CHAIN 19..380;  /note=\"Kininogen-1 heavy chain\";  /id=\"PRO_0000006686\"; CHAIN 390..644;  /note=\"Kininogen-1 light chain\";  /id=\"PRO_0000006689\"'],\n",
       "      dtype=object)"
      ]
     },
     "execution_count": 19,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.query(\"Entry == 'P01042'\")['Chain'].values"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array(['PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_0000372485\"; PEPTIDE 380..389;  /note=\"Lysyl-bradykinin\";  /id=\"PRO_0000006687\"; PEPTIDE 381..389;  /note=\"Bradykinin\";  /id=\"PRO_0000006688\"; PEPTIDE 431..434;  /note=\"Low molecular weight growth-promoting factor\";  /id=\"PRO_0000006690\"'],\n",
       "      dtype=object)"
      ]
     },
     "execution_count": 20,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.query(\"Entry == 'P01042'\")['Peptide'].values"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {},
   "outputs": [],
   "source": [
    "def parse_feature_record(record, feature_type):\n",
    "    items = record.split(';')\n",
    "    feature = np.empty(5, dtype=object)\n",
    "        \n",
    "    feature[0] = feature_type\n",
    "    for item in items:\n",
    "        item = item.strip()\n",
    "        if '..' in item:\n",
    "            start_end = item.split('..')\n",
    "            # in a few cases a '?' is used to represent an unknown start or end, check if it's a digit\n",
    "            if start_end[0].isdigit():\n",
    "                feature[1] = start_end[0]\n",
    "            else:\n",
    "                feature[1] = ''\n",
    "            if start_end[1].isdigit():\n",
    "                feature[2] = start_end[1]\n",
    "            else:\n",
    "                feature[2] = ''\n",
    "        elif item.startswith(\"/note=\"):\n",
    "            name = item[6:].replace('\\\"', '')\n",
    "            feature[3] = name\n",
    "        elif item.startswith(\"/id=\"):\n",
    "            pro_id = item[4:].replace('\\\"', '')\n",
    "            feature[4] = 'uniprot.chain:' + pro_id\n",
    "                \n",
    "    return feature"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {},
   "outputs": [],
   "source": [
    "def parse_features(row):\n",
    "    chain_features = []\n",
    "    if 'CHAIN' in row['Chain']:\n",
    "        chains = row['Chain'].split('CHAIN')\n",
    "        if chains[0] == '':\n",
    "            chains = chains[1:]\n",
    "        chain_features = [parse_feature_record(chain, 'CHAIN') for chain in chains]\n",
    "\n",
    "    protein_features = []\n",
    "    # Full-length (coding sequence) proteins are inconsistenly handled in UniProt. \n",
    "    # For some entries, the full-length protein is included\n",
    "    # in the chain features (e.g. P0DTD1), for others it's not (e.g., P01042)\n",
    "    # Check if full-length protein is included in chain list\n",
    "    full_length = False\n",
    "    for f in chain_features:\n",
    "        if f[1] == '1' and f[2] == row['Length']:\n",
    "            full_length = True\n",
    "            break\n",
    "    # Add entry if full-length protein is not in chain list\n",
    "    if not full_length:\n",
    "        protein_name = row['Protein names'].split('(')[0]\n",
    "        protein_features = [np.array(['PROTEIN','1', row['Length'], protein_name,''], dtype=object)]\n",
    "            \n",
    "    peptide_features = []\n",
    "    if 'PEPTIDE' in row['Peptide']:\n",
    "        peptides = row['Peptide'].split('PEPTIDE')\n",
    "        if peptides[0] == '':\n",
    "            peptides = peptides[1:]\n",
    "        peptide_features = [parse_feature_record(peptide, 'PEPTIDE') for peptide in peptides]\n",
    "    \n",
    "    return protein_features + chain_features + peptide_features"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['Features'] = unp.apply(parse_features, axis=1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp = unp.explode('Features')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp[['type', 'start', 'end', 'name', 'proId']] = unp.apply(lambda row: row['Features'], axis=1, result_type=\"expand\")"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Handle missing values"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp.fillna('', inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Entry</th>\n",
       "      <th>Entry name</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>Length</th>\n",
       "      <th>Protein names</th>\n",
       "      <th>Status</th>\n",
       "      <th>Organism ID</th>\n",
       "      <th>Chain</th>\n",
       "      <th>Peptide</th>\n",
       "      <th>Gene ontology (biological process)</th>\n",
       "      <th>reviewed</th>\n",
       "      <th>synonymes</th>\n",
       "      <th>Features</th>\n",
       "      <th>type</th>\n",
       "      <th>start</th>\n",
       "      <th>end</th>\n",
       "      <th>name</th>\n",
       "      <th>proId</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>P0DTC5</td>\n",
       "      <td>VME1_SARS2</td>\n",
       "      <td>MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein (M) (E1 glycoprotein) (Matrix...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..222;  /note=\"Membrane protein\";  /id=...</td>\n",
       "      <td></td>\n",
       "      <td>mitigation of host immune response by virus [G...</td>\n",
       "      <td>True</td>\n",
       "      <td>Membrane protein;M;E1 glycoprotein;Matrix glyc...</td>\n",
       "      <td>[CHAIN, 1, 222, Membrane protein, uniprot.chai...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449652</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 1, 4405, Replicase polyprotein 1a, uni...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a</td>\n",
       "      <td>uniprot.chain:PRO_0000449634</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 1, 180, Host translation inhibitor nsp...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>180</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>uniprot.chain:PRO_0000449635</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 181, 818, Non-structural protein 2, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>181</td>\n",
       "      <td>818</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>uniprot.chain:PRO_0000449636</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 819, 2763, Non-structural protein 3, u...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>819</td>\n",
       "      <td>2763</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>uniprot.chain:PRO_0000449637</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 2764, 3263, Non-structural protein 4, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>2764</td>\n",
       "      <td>3263</td>\n",
       "      <td>Non-structural protein 4</td>\n",
       "      <td>uniprot.chain:PRO_0000449638</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 3264, 3569, 3C-like proteinase, unipro...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3264</td>\n",
       "      <td>3569</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td>uniprot.chain:PRO_0000449639</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 3570, 3859, Non-structural protein 6, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3570</td>\n",
       "      <td>3859</td>\n",
       "      <td>Non-structural protein 6</td>\n",
       "      <td>uniprot.chain:PRO_0000449640</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 3860, 3942, Non-structural protein 7, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3860</td>\n",
       "      <td>3942</td>\n",
       "      <td>Non-structural protein 7</td>\n",
       "      <td>uniprot.chain:PRO_0000449641</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 3943, 4140, Non-structural protein 8, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3943</td>\n",
       "      <td>4140</td>\n",
       "      <td>Non-structural protein 8</td>\n",
       "      <td>uniprot.chain:PRO_0000449642</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 4141, 4253, Non-structural protein 9, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4141</td>\n",
       "      <td>4253</td>\n",
       "      <td>Non-structural protein 9</td>\n",
       "      <td>uniprot.chain:PRO_0000449643</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 4254, 4392, Non-structural protein 10,...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4254</td>\n",
       "      <td>4392</td>\n",
       "      <td>Non-structural protein 10</td>\n",
       "      <td>uniprot.chain:PRO_0000449644</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 4393, 4405, Non-structural protein 11,...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4393</td>\n",
       "      <td>4405</td>\n",
       "      <td>Non-structural protein 11</td>\n",
       "      <td>uniprot.chain:PRO_0000449645</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>P0DTD3</td>\n",
       "      <td>Y14_SARS2</td>\n",
       "      <td>MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...</td>\n",
       "      <td>73</td>\n",
       "      <td>Uncharacterized protein 14 (ORF14)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..73;  /note=\"Uncharacterized protein 1...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>Uncharacterized protein 14;ORF14</td>\n",
       "      <td>[CHAIN, 1, 73, Uncharacterized protein 14, uni...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>73</td>\n",
       "      <td>Uncharacterized protein 14</td>\n",
       "      <td>uniprot.chain:PRO_0000449658</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>P0DTC4</td>\n",
       "      <td>VEMP_SARS2</td>\n",
       "      <td>MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein (E) (sM protein)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..75;  /note=\"Envelope small membrane p...</td>\n",
       "      <td></td>\n",
       "      <td>pore formation by virus in membrane of host ce...</td>\n",
       "      <td>True</td>\n",
       "      <td>Envelope small membrane protein;E;sM protein</td>\n",
       "      <td>[CHAIN, 1, 75, Envelope small membrane protein...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449651</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "      <td>[PROTEIN, 1, 1273, Spike glycoprotein , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "      <td>[CHAIN, 13, 1273, Spike glycoprotein, uniprot....</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>13</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein</td>\n",
       "      <td>uniprot.chain:PRO_0000449646</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "      <td>[CHAIN, 13, 685, Spike protein S1, uniprot.cha...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>13</td>\n",
       "      <td>685</td>\n",
       "      <td>Spike protein S1</td>\n",
       "      <td>uniprot.chain:PRO_0000449647</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "      <td>[CHAIN, 686, 1273, Spike protein S2, uniprot.c...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>686</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike protein S2</td>\n",
       "      <td>uniprot.chain:PRO_0000449648</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "      <td>[CHAIN, 816, 1273, Spike protein S2', uniprot....</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>816</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike protein S2'</td>\n",
       "      <td>uniprot.chain:PRO_0000449649</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>P0DTC9</td>\n",
       "      <td>NCAP_SARS2</td>\n",
       "      <td>MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLP...</td>\n",
       "      <td>419</td>\n",
       "      <td>Nucleoprotein (N) (Nucleocapsid protein) (NC) ...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..419;  /note=\"Nucleoprotein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>Nucleoprotein;N;Nucleocapsid protein;NC;Protein N</td>\n",
       "      <td>[CHAIN, 1, 419, Nucleoprotein, uniprot.chain:P...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>419</td>\n",
       "      <td>Nucleoprotein</td>\n",
       "      <td>uniprot.chain:PRO_0000449656</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>P0DTC8</td>\n",
       "      <td>NS8_SARS2</td>\n",
       "      <td>MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein (ORF8) (Non-structural protein 8)...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>ORF8 protein;ORF8;Non-structural protein 8;ns8</td>\n",
       "      <td>[PROTEIN, 1, 121, ORF8 protein , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>P0DTC8</td>\n",
       "      <td>NS8_SARS2</td>\n",
       "      <td>MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein (ORF8) (Non-structural protein 8)...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>ORF8 protein;ORF8;Non-structural protein 8;ns8</td>\n",
       "      <td>[CHAIN, 16, 121, ORF8 protein, uniprot.chain:P...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>16</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449655</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>P0DTD8</td>\n",
       "      <td>NS7B_SARS2</td>\n",
       "      <td>MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA</td>\n",
       "      <td>43</td>\n",
       "      <td>ORF7b protein (ORF7b) (Accessory protein 7b)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..43;  /note=\"ORF7b protein\";  /id=\"PRO...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>ORF7b protein;ORF7b;Accessory protein 7b</td>\n",
       "      <td>[CHAIN, 1, 43, ORF7b protein, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>43</td>\n",
       "      <td>ORF7b protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449799</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>P0DTC7</td>\n",
       "      <td>NS7A_SARS2</td>\n",
       "      <td>MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein (ORF7a) (Accessory protein 7a) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...</td>\n",
       "      <td></td>\n",
       "      <td>modulation by virus of host G0/G1 transition c...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF7a protein;ORF7a;Accessory protein 7a;Prote...</td>\n",
       "      <td>[PROTEIN, 1, 121, ORF7a protein , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>P0DTC7</td>\n",
       "      <td>NS7A_SARS2</td>\n",
       "      <td>MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein (ORF7a) (Accessory protein 7a) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...</td>\n",
       "      <td></td>\n",
       "      <td>modulation by virus of host G0/G1 transition c...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF7a protein;ORF7a;Accessory protein 7a;Prote...</td>\n",
       "      <td>[CHAIN, 16, 121, ORF7a protein, uniprot.chain:...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>16</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449654</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>P0DTD2</td>\n",
       "      <td>ORF9B_SARS2</td>\n",
       "      <td>MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIIL...</td>\n",
       "      <td>97</td>\n",
       "      <td>ORF9b protein (ORF9b) (Accessory protein 9b) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..97;  /note=\"ORF9b protein\";  /evidenc...</td>\n",
       "      <td></td>\n",
       "      <td>suppression by virus of host MAVS activity [GO...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF9b protein;ORF9b;Accessory protein 9b;ORF-9...</td>\n",
       "      <td>[CHAIN, 1, 97, ORF9b protein, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>97</td>\n",
       "      <td>ORF9b protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449657</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 1, 7096, Replicase polyprotein 1ab, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab</td>\n",
       "      <td>uniprot.chain:PRO_0000449618</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 1, 180, Host translation inhibitor nsp...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>180</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>uniprot.chain:PRO_0000449619</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 181, 818, Non-structural protein 2, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>181</td>\n",
       "      <td>818</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>uniprot.chain:PRO_0000449620</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 819, 2763, Non-structural protein 3, u...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>819</td>\n",
       "      <td>2763</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>uniprot.chain:PRO_0000449621</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 2764, 3263, Non-structural protein 4, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>2764</td>\n",
       "      <td>3263</td>\n",
       "      <td>Non-structural protein 4</td>\n",
       "      <td>uniprot.chain:PRO_0000449622</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 3264, 3569, 3C-like proteinase, unipro...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3264</td>\n",
       "      <td>3569</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td>uniprot.chain:PRO_0000449623</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 3570, 3859, Non-structural protein 6, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3570</td>\n",
       "      <td>3859</td>\n",
       "      <td>Non-structural protein 6</td>\n",
       "      <td>uniprot.chain:PRO_0000449624</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 3860, 3942, Non-structural protein 7, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3860</td>\n",
       "      <td>3942</td>\n",
       "      <td>Non-structural protein 7</td>\n",
       "      <td>uniprot.chain:PRO_0000449625</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 3943, 4140, Non-structural protein 8, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3943</td>\n",
       "      <td>4140</td>\n",
       "      <td>Non-structural protein 8</td>\n",
       "      <td>uniprot.chain:PRO_0000449626</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 4141, 4253, Non-structural protein 9, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4141</td>\n",
       "      <td>4253</td>\n",
       "      <td>Non-structural protein 9</td>\n",
       "      <td>uniprot.chain:PRO_0000449627</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 4254, 4392, Non-structural protein 10,...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4254</td>\n",
       "      <td>4392</td>\n",
       "      <td>Non-structural protein 10</td>\n",
       "      <td>uniprot.chain:PRO_0000449628</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 4393, 5324, RNA-directed RNA polymeras...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4393</td>\n",
       "      <td>5324</td>\n",
       "      <td>RNA-directed RNA polymerase</td>\n",
       "      <td>uniprot.chain:PRO_0000449629</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 5325, 5925, Helicase, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>5325</td>\n",
       "      <td>5925</td>\n",
       "      <td>Helicase</td>\n",
       "      <td>uniprot.chain:PRO_0000449630</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 5926, 6452, Proofreading exoribonuclea...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>5926</td>\n",
       "      <td>6452</td>\n",
       "      <td>Proofreading exoribonuclease</td>\n",
       "      <td>uniprot.chain:PRO_0000449631</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 6453, 6798, Uridylate-specific endorib...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>6453</td>\n",
       "      <td>6798</td>\n",
       "      <td>Uridylate-specific endoribonuclease</td>\n",
       "      <td>uniprot.chain:PRO_0000449632</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 6799, 7096, 2'-O-methyltransferase, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>6799</td>\n",
       "      <td>7096</td>\n",
       "      <td>2'-O-methyltransferase</td>\n",
       "      <td>uniprot.chain:PRO_0000449633</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>P0DTC3</td>\n",
       "      <td>AP3A_SARS2</td>\n",
       "      <td>MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWL...</td>\n",
       "      <td>275</td>\n",
       "      <td>ORF3a protein (ORF3a) (Accessory protein 3a) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..275;  /note=\"ORF3a protein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td>pore formation by virus in membrane of host ce...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF3a protein;ORF3a;Accessory protein 3a;Prote...</td>\n",
       "      <td>[CHAIN, 1, 275, ORF3a protein, uniprot.chain:P...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>275</td>\n",
       "      <td>ORF3a protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449650</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>P0DTC6</td>\n",
       "      <td>NS6_SARS2</td>\n",
       "      <td>MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTE...</td>\n",
       "      <td>61</td>\n",
       "      <td>ORF6 protein (ORF6) (Accessory protein 6) (Non...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..61;  /note=\"ORF6 protein\";  /id=\"PRO_...</td>\n",
       "      <td></td>\n",
       "      <td>pathogenesis [GO:0009405]</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF6 protein;ORF6;Accessory protein 6;Non-stru...</td>\n",
       "      <td>[CHAIN, 1, 61, ORF6 protein, uniprot.chain:PRO...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>61</td>\n",
       "      <td>ORF6 protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449653</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>A0A7D4BMC0</td>\n",
       "      <td>A0A7D4BMC0_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>ORF1a polyprotein</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>ORF1a polyprotein</td>\n",
       "      <td>[PROTEIN, 1, 4405, ORF1a polyprotein, ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>ORF1a polyprotein</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>A0A6M6J105</td>\n",
       "      <td>A0A6M6J105_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>3C-like proteinase (EC 3.4.19.12) (EC 3.4.22.6...</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>3C-like proteinase;EC 3.4.19.12;EC 3.4.22.69;G...</td>\n",
       "      <td>[PROTEIN, 1, 4405, 3C-like proteinase , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>A0A6H0JIU7</td>\n",
       "      <td>A0A6H0JIU7_SARS2</td>\n",
       "      <td>MIELSLIDFYLCXLAFLLFLVLIMLIIFWFSLELQDHNETCHA</td>\n",
       "      <td>43</td>\n",
       "      <td>Accessory protein 7b</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>Accessory protein 7b</td>\n",
       "      <td>[PROTEIN, 1, 43, Accessory protein 7b, ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>43</td>\n",
       "      <td>Accessory protein 7b</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>A0A6M4N1G6</td>\n",
       "      <td>A0A6M4N1G6_SARS2</td>\n",
       "      <td>MYSFVSEETGTLIXNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein (E protein) (s...</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>Envelope small membrane protein;E protein;sM p...</td>\n",
       "      <td>[PROTEIN, 1, 75, Envelope small membrane prote...</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>A0A7D7KXN3</td>\n",
       "      <td>A0A7D7KXN3_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Surface glycoprotein</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>Surface glycoprotein</td>\n",
       "      <td>[PROTEIN, 1, 1273, Surface glycoprotein, ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>1273</td>\n",
       "      <td>Surface glycoprotein</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "         Entry        Entry name  \\\n",
       "0       P0DTC5        VME1_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "2       P0DTD3         Y14_SARS2   \n",
       "3       P0DTC4        VEMP_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "5       P0DTC9        NCAP_SARS2   \n",
       "6       P0DTC8         NS8_SARS2   \n",
       "6       P0DTC8         NS8_SARS2   \n",
       "7       P0DTD8        NS7B_SARS2   \n",
       "8       P0DTC7        NS7A_SARS2   \n",
       "8       P0DTC7        NS7A_SARS2   \n",
       "9       P0DTD2       ORF9B_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "11      P0DTC3        AP3A_SARS2   \n",
       "12      P0DTC6         NS6_SARS2   \n",
       "13  A0A7D4BMC0  A0A7D4BMC0_SARS2   \n",
       "14  A0A6M6J105  A0A6M6J105_SARS2   \n",
       "15  A0A6H0JIU7  A0A6H0JIU7_SARS2   \n",
       "16  A0A6M4N1G6  A0A6M4N1G6_SARS2   \n",
       "17  A0A7D7KXN3  A0A7D7KXN3_SARS2   \n",
       "\n",
       "                                             Sequence Length  \\\n",
       "0   MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...    222   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "2   MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...     73   \n",
       "3   MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...     75   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "5   MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLP...    419   \n",
       "6   MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...    121   \n",
       "6   MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...    121   \n",
       "7         MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA     43   \n",
       "8   MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...    121   \n",
       "8   MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...    121   \n",
       "9   MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIIL...     97   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "11  MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWL...    275   \n",
       "12  MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTE...     61   \n",
       "13  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "14  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "15        MIELSLIDFYLCXLAFLLFLVLIMLIIFWFSLELQDHNETCHA     43   \n",
       "16  MYSFVSEETGTLIXNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...     75   \n",
       "17  MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "\n",
       "                                        Protein names      Status Organism ID  \\\n",
       "0   Membrane protein (M) (E1 glycoprotein) (Matrix...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "2                  Uncharacterized protein 14 (ORF14)    reviewed     2697049   \n",
       "3    Envelope small membrane protein (E) (sM protein)    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "5   Nucleoprotein (N) (Nucleocapsid protein) (NC) ...    reviewed     2697049   \n",
       "6   ORF8 protein (ORF8) (Non-structural protein 8)...    reviewed     2697049   \n",
       "6   ORF8 protein (ORF8) (Non-structural protein 8)...    reviewed     2697049   \n",
       "7        ORF7b protein (ORF7b) (Accessory protein 7b)    reviewed     2697049   \n",
       "8   ORF7a protein (ORF7a) (Accessory protein 7a) (...    reviewed     2697049   \n",
       "8   ORF7a protein (ORF7a) (Accessory protein 7a) (...    reviewed     2697049   \n",
       "9   ORF9b protein (ORF9b) (Accessory protein 9b) (...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "11  ORF3a protein (ORF3a) (Accessory protein 3a) (...    reviewed     2697049   \n",
       "12  ORF6 protein (ORF6) (Accessory protein 6) (Non...    reviewed     2697049   \n",
       "13                                  ORF1a polyprotein  unreviewed     2697049   \n",
       "14  3C-like proteinase (EC 3.4.19.12) (EC 3.4.22.6...  unreviewed     2697049   \n",
       "15                               Accessory protein 7b  unreviewed     2697049   \n",
       "16  Envelope small membrane protein (E protein) (s...  unreviewed     2697049   \n",
       "17                               Surface glycoprotein  unreviewed     2697049   \n",
       "\n",
       "                                                Chain Peptide  \\\n",
       "0   CHAIN 1..222;  /note=\"Membrane protein\";  /id=...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "2   CHAIN 1..73;  /note=\"Uncharacterized protein 1...           \n",
       "3   CHAIN 1..75;  /note=\"Envelope small membrane p...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "5   CHAIN 1..419;  /note=\"Nucleoprotein\";  /id=\"PR...           \n",
       "6   CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...           \n",
       "6   CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...           \n",
       "7   CHAIN 1..43;  /note=\"ORF7b protein\";  /id=\"PRO...           \n",
       "8   CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...           \n",
       "8   CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...           \n",
       "9   CHAIN 1..97;  /note=\"ORF9b protein\";  /evidenc...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "11  CHAIN 1..275;  /note=\"ORF3a protein\";  /id=\"PR...           \n",
       "12  CHAIN 1..61;  /note=\"ORF6 protein\";  /id=\"PRO_...           \n",
       "13                                                              \n",
       "14                                                              \n",
       "15                                                              \n",
       "16                                                              \n",
       "17                                                              \n",
       "\n",
       "                   Gene ontology (biological process) reviewed  \\\n",
       "0   mitigation of host immune response by virus [G...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "2                                                         True   \n",
       "3   pore formation by virus in membrane of host ce...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "5                                                         True   \n",
       "6                                                         True   \n",
       "6                                                         True   \n",
       "7                                                         True   \n",
       "8   modulation by virus of host G0/G1 transition c...     True   \n",
       "8   modulation by virus of host G0/G1 transition c...     True   \n",
       "9   suppression by virus of host MAVS activity [GO...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "11  pore formation by virus in membrane of host ce...     True   \n",
       "12                          pathogenesis [GO:0009405]     True   \n",
       "13                                                       False   \n",
       "14                                                       False   \n",
       "15                                                       False   \n",
       "16                                                       False   \n",
       "17                                                       False   \n",
       "\n",
       "                                            synonymes  \\\n",
       "0   Membrane protein;M;E1 glycoprotein;Matrix glyc...   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "2                    Uncharacterized protein 14;ORF14   \n",
       "3        Envelope small membrane protein;E;sM protein   \n",
       "4   Spike glycoprotein;S glycoprotein;E2;Peplomer ...   \n",
       "4   Spike glycoprotein;S glycoprotein;E2;Peplomer ...   \n",
       "4   Spike glycoprotein;S glycoprotein;E2;Peplomer ...   \n",
       "4   Spike glycoprotein;S glycoprotein;E2;Peplomer ...   \n",
       "4   Spike glycoprotein;S glycoprotein;E2;Peplomer ...   \n",
       "5   Nucleoprotein;N;Nucleocapsid protein;NC;Protein N   \n",
       "6      ORF8 protein;ORF8;Non-structural protein 8;ns8   \n",
       "6      ORF8 protein;ORF8;Non-structural protein 8;ns8   \n",
       "7            ORF7b protein;ORF7b;Accessory protein 7b   \n",
       "8   ORF7a protein;ORF7a;Accessory protein 7a;Prote...   \n",
       "8   ORF7a protein;ORF7a;Accessory protein 7a;Prote...   \n",
       "9   ORF9b protein;ORF9b;Accessory protein 9b;ORF-9...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "11  ORF3a protein;ORF3a;Accessory protein 3a;Prote...   \n",
       "12  ORF6 protein;ORF6;Accessory protein 6;Non-stru...   \n",
       "13                                  ORF1a polyprotein   \n",
       "14  3C-like proteinase;EC 3.4.19.12;EC 3.4.22.69;G...   \n",
       "15                               Accessory protein 7b   \n",
       "16  Envelope small membrane protein;E protein;sM p...   \n",
       "17                               Surface glycoprotein   \n",
       "\n",
       "                                             Features     type start   end  \\\n",
       "0   [CHAIN, 1, 222, Membrane protein, uniprot.chai...    CHAIN     1   222   \n",
       "1   [CHAIN, 1, 4405, Replicase polyprotein 1a, uni...    CHAIN     1  4405   \n",
       "1   [CHAIN, 1, 180, Host translation inhibitor nsp...    CHAIN     1   180   \n",
       "1   [CHAIN, 181, 818, Non-structural protein 2, un...    CHAIN   181   818   \n",
       "1   [CHAIN, 819, 2763, Non-structural protein 3, u...    CHAIN   819  2763   \n",
       "1   [CHAIN, 2764, 3263, Non-structural protein 4, ...    CHAIN  2764  3263   \n",
       "1   [CHAIN, 3264, 3569, 3C-like proteinase, unipro...    CHAIN  3264  3569   \n",
       "1   [CHAIN, 3570, 3859, Non-structural protein 6, ...    CHAIN  3570  3859   \n",
       "1   [CHAIN, 3860, 3942, Non-structural protein 7, ...    CHAIN  3860  3942   \n",
       "1   [CHAIN, 3943, 4140, Non-structural protein 8, ...    CHAIN  3943  4140   \n",
       "1   [CHAIN, 4141, 4253, Non-structural protein 9, ...    CHAIN  4141  4253   \n",
       "1   [CHAIN, 4254, 4392, Non-structural protein 10,...    CHAIN  4254  4392   \n",
       "1   [CHAIN, 4393, 4405, Non-structural protein 11,...    CHAIN  4393  4405   \n",
       "2   [CHAIN, 1, 73, Uncharacterized protein 14, uni...    CHAIN     1    73   \n",
       "3   [CHAIN, 1, 75, Envelope small membrane protein...    CHAIN     1    75   \n",
       "4           [PROTEIN, 1, 1273, Spike glycoprotein , ]  PROTEIN     1  1273   \n",
       "4   [CHAIN, 13, 1273, Spike glycoprotein, uniprot....    CHAIN    13  1273   \n",
       "4   [CHAIN, 13, 685, Spike protein S1, uniprot.cha...    CHAIN    13   685   \n",
       "4   [CHAIN, 686, 1273, Spike protein S2, uniprot.c...    CHAIN   686  1273   \n",
       "4   [CHAIN, 816, 1273, Spike protein S2', uniprot....    CHAIN   816  1273   \n",
       "5   [CHAIN, 1, 419, Nucleoprotein, uniprot.chain:P...    CHAIN     1   419   \n",
       "6                  [PROTEIN, 1, 121, ORF8 protein , ]  PROTEIN     1   121   \n",
       "6   [CHAIN, 16, 121, ORF8 protein, uniprot.chain:P...    CHAIN    16   121   \n",
       "7   [CHAIN, 1, 43, ORF7b protein, uniprot.chain:PR...    CHAIN     1    43   \n",
       "8                 [PROTEIN, 1, 121, ORF7a protein , ]  PROTEIN     1   121   \n",
       "8   [CHAIN, 16, 121, ORF7a protein, uniprot.chain:...    CHAIN    16   121   \n",
       "9   [CHAIN, 1, 97, ORF9b protein, uniprot.chain:PR...    CHAIN     1    97   \n",
       "10  [CHAIN, 1, 7096, Replicase polyprotein 1ab, un...    CHAIN     1  7096   \n",
       "10  [CHAIN, 1, 180, Host translation inhibitor nsp...    CHAIN     1   180   \n",
       "10  [CHAIN, 181, 818, Non-structural protein 2, un...    CHAIN   181   818   \n",
       "10  [CHAIN, 819, 2763, Non-structural protein 3, u...    CHAIN   819  2763   \n",
       "10  [CHAIN, 2764, 3263, Non-structural protein 4, ...    CHAIN  2764  3263   \n",
       "10  [CHAIN, 3264, 3569, 3C-like proteinase, unipro...    CHAIN  3264  3569   \n",
       "10  [CHAIN, 3570, 3859, Non-structural protein 6, ...    CHAIN  3570  3859   \n",
       "10  [CHAIN, 3860, 3942, Non-structural protein 7, ...    CHAIN  3860  3942   \n",
       "10  [CHAIN, 3943, 4140, Non-structural protein 8, ...    CHAIN  3943  4140   \n",
       "10  [CHAIN, 4141, 4253, Non-structural protein 9, ...    CHAIN  4141  4253   \n",
       "10  [CHAIN, 4254, 4392, Non-structural protein 10,...    CHAIN  4254  4392   \n",
       "10  [CHAIN, 4393, 5324, RNA-directed RNA polymeras...    CHAIN  4393  5324   \n",
       "10  [CHAIN, 5325, 5925, Helicase, uniprot.chain:PR...    CHAIN  5325  5925   \n",
       "10  [CHAIN, 5926, 6452, Proofreading exoribonuclea...    CHAIN  5926  6452   \n",
       "10  [CHAIN, 6453, 6798, Uridylate-specific endorib...    CHAIN  6453  6798   \n",
       "10  [CHAIN, 6799, 7096, 2'-O-methyltransferase, un...    CHAIN  6799  7096   \n",
       "11  [CHAIN, 1, 275, ORF3a protein, uniprot.chain:P...    CHAIN     1   275   \n",
       "12  [CHAIN, 1, 61, ORF6 protein, uniprot.chain:PRO...    CHAIN     1    61   \n",
       "13            [PROTEIN, 1, 4405, ORF1a polyprotein, ]  PROTEIN     1  4405   \n",
       "14          [PROTEIN, 1, 4405, 3C-like proteinase , ]  PROTEIN     1  4405   \n",
       "15           [PROTEIN, 1, 43, Accessory protein 7b, ]  PROTEIN     1    43   \n",
       "16  [PROTEIN, 1, 75, Envelope small membrane prote...  PROTEIN     1    75   \n",
       "17         [PROTEIN, 1, 1273, Surface glycoprotein, ]  PROTEIN     1  1273   \n",
       "\n",
       "                                   name                         proId  \n",
       "0                      Membrane protein  uniprot.chain:PRO_0000449652  \n",
       "1              Replicase polyprotein 1a  uniprot.chain:PRO_0000449634  \n",
       "1       Host translation inhibitor nsp1  uniprot.chain:PRO_0000449635  \n",
       "1              Non-structural protein 2  uniprot.chain:PRO_0000449636  \n",
       "1              Non-structural protein 3  uniprot.chain:PRO_0000449637  \n",
       "1              Non-structural protein 4  uniprot.chain:PRO_0000449638  \n",
       "1                    3C-like proteinase  uniprot.chain:PRO_0000449639  \n",
       "1              Non-structural protein 6  uniprot.chain:PRO_0000449640  \n",
       "1              Non-structural protein 7  uniprot.chain:PRO_0000449641  \n",
       "1              Non-structural protein 8  uniprot.chain:PRO_0000449642  \n",
       "1              Non-structural protein 9  uniprot.chain:PRO_0000449643  \n",
       "1             Non-structural protein 10  uniprot.chain:PRO_0000449644  \n",
       "1             Non-structural protein 11  uniprot.chain:PRO_0000449645  \n",
       "2            Uncharacterized protein 14  uniprot.chain:PRO_0000449658  \n",
       "3       Envelope small membrane protein  uniprot.chain:PRO_0000449651  \n",
       "4                   Spike glycoprotein                                 \n",
       "4                    Spike glycoprotein  uniprot.chain:PRO_0000449646  \n",
       "4                      Spike protein S1  uniprot.chain:PRO_0000449647  \n",
       "4                      Spike protein S2  uniprot.chain:PRO_0000449648  \n",
       "4                     Spike protein S2'  uniprot.chain:PRO_0000449649  \n",
       "5                         Nucleoprotein  uniprot.chain:PRO_0000449656  \n",
       "6                         ORF8 protein                                 \n",
       "6                          ORF8 protein  uniprot.chain:PRO_0000449655  \n",
       "7                         ORF7b protein  uniprot.chain:PRO_0000449799  \n",
       "8                        ORF7a protein                                 \n",
       "8                         ORF7a protein  uniprot.chain:PRO_0000449654  \n",
       "9                         ORF9b protein  uniprot.chain:PRO_0000449657  \n",
       "10            Replicase polyprotein 1ab  uniprot.chain:PRO_0000449618  \n",
       "10      Host translation inhibitor nsp1  uniprot.chain:PRO_0000449619  \n",
       "10             Non-structural protein 2  uniprot.chain:PRO_0000449620  \n",
       "10             Non-structural protein 3  uniprot.chain:PRO_0000449621  \n",
       "10             Non-structural protein 4  uniprot.chain:PRO_0000449622  \n",
       "10                   3C-like proteinase  uniprot.chain:PRO_0000449623  \n",
       "10             Non-structural protein 6  uniprot.chain:PRO_0000449624  \n",
       "10             Non-structural protein 7  uniprot.chain:PRO_0000449625  \n",
       "10             Non-structural protein 8  uniprot.chain:PRO_0000449626  \n",
       "10             Non-structural protein 9  uniprot.chain:PRO_0000449627  \n",
       "10            Non-structural protein 10  uniprot.chain:PRO_0000449628  \n",
       "10          RNA-directed RNA polymerase  uniprot.chain:PRO_0000449629  \n",
       "10                             Helicase  uniprot.chain:PRO_0000449630  \n",
       "10         Proofreading exoribonuclease  uniprot.chain:PRO_0000449631  \n",
       "10  Uridylate-specific endoribonuclease  uniprot.chain:PRO_0000449632  \n",
       "10               2'-O-methyltransferase  uniprot.chain:PRO_0000449633  \n",
       "11                        ORF3a protein  uniprot.chain:PRO_0000449650  \n",
       "12                         ORF6 protein  uniprot.chain:PRO_0000449653  \n",
       "13                    ORF1a polyprotein                                \n",
       "14                  3C-like proteinase                                 \n",
       "15                 Accessory protein 7b                                \n",
       "16     Envelope small membrane protein                                 \n",
       "17                 Surface glycoprotein                                "
      ]
     },
     "execution_count": 27,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.head(50)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Cleave sequences into peptides"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 28,
   "metadata": {},
   "outputs": [],
   "source": [
    "def get_subsequence(row):\n",
    "    if row['start'].isdigit() and row['end'].isdigit():\n",
    "        start = int(row['start'])\n",
    "        end = int(row['end'])\n",
    "        sequence = row['Sequence']\n",
    "        return sequence[start-1: end]\n",
    "    else:\n",
    "        return ''"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 29,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['sequence'] = unp.apply(lambda row: get_subsequence(row), axis=1)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Set flag if protein chain is full length"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 30,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['fullLength'] = (unp['start'] == '1') & (unp['end'] == unp['Length'])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 31,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['name'] = unp['name'].str.strip()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 32,
   "metadata": {},
   "outputs": [],
   "source": [
    "def set_synonymes(row):\n",
    "    if row['fullLength']:\n",
    "        return row['synonymes']\n",
    "    else:\n",
    "        return row['name']"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Cleaved protein, should not inherit synonymes from the full length protein"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['synonymes'] = unp.apply(set_synonymes, axis=1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 34,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Entry</th>\n",
       "      <th>Entry name</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>Length</th>\n",
       "      <th>Protein names</th>\n",
       "      <th>Status</th>\n",
       "      <th>Organism ID</th>\n",
       "      <th>Chain</th>\n",
       "      <th>Peptide</th>\n",
       "      <th>Gene ontology (biological process)</th>\n",
       "      <th>reviewed</th>\n",
       "      <th>synonymes</th>\n",
       "      <th>Features</th>\n",
       "      <th>type</th>\n",
       "      <th>start</th>\n",
       "      <th>end</th>\n",
       "      <th>name</th>\n",
       "      <th>proId</th>\n",
       "      <th>sequence</th>\n",
       "      <th>fullLength</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>P0DTC5</td>\n",
       "      <td>VME1_SARS2</td>\n",
       "      <td>MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein (M) (E1 glycoprotein) (Matrix...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..222;  /note=\"Membrane protein\";  /id=...</td>\n",
       "      <td></td>\n",
       "      <td>mitigation of host immune response by virus [G...</td>\n",
       "      <td>True</td>\n",
       "      <td>Membrane protein;M;E1 glycoprotein;Matrix glyc...</td>\n",
       "      <td>[CHAIN, 1, 222, Membrane protein, uniprot.chai...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449652</td>\n",
       "      <td>MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 1, 4405, Replicase polyprotein 1a, uni...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a</td>\n",
       "      <td>uniprot.chain:PRO_0000449634</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>[CHAIN, 1, 180, Host translation inhibitor nsp...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>180</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>uniprot.chain:PRO_0000449635</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>[CHAIN, 181, 818, Non-structural protein 2, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>181</td>\n",
       "      <td>818</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>uniprot.chain:PRO_0000449636</td>\n",
       "      <td>AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKR...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>[CHAIN, 819, 2763, Non-structural protein 3, u...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>819</td>\n",
       "      <td>2763</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>uniprot.chain:PRO_0000449637</td>\n",
       "      <td>APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVEL...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 4</td>\n",
       "      <td>[CHAIN, 2764, 3263, Non-structural protein 4, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>2764</td>\n",
       "      <td>3263</td>\n",
       "      <td>Non-structural protein 4</td>\n",
       "      <td>uniprot.chain:PRO_0000449638</td>\n",
       "      <td>KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td>[CHAIN, 3264, 3569, 3C-like proteinase, unipro...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3264</td>\n",
       "      <td>3569</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td>uniprot.chain:PRO_0000449639</td>\n",
       "      <td>SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 6</td>\n",
       "      <td>[CHAIN, 3570, 3859, Non-structural protein 6, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3570</td>\n",
       "      <td>3859</td>\n",
       "      <td>Non-structural protein 6</td>\n",
       "      <td>uniprot.chain:PRO_0000449640</td>\n",
       "      <td>SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFA...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 7</td>\n",
       "      <td>[CHAIN, 3860, 3942, Non-structural protein 7, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3860</td>\n",
       "      <td>3942</td>\n",
       "      <td>Non-structural protein 7</td>\n",
       "      <td>uniprot.chain:PRO_0000449641</td>\n",
       "      <td>SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTT...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 8</td>\n",
       "      <td>[CHAIN, 3943, 4140, Non-structural protein 8, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3943</td>\n",
       "      <td>4140</td>\n",
       "      <td>Non-structural protein 8</td>\n",
       "      <td>uniprot.chain:PRO_0000449642</td>\n",
       "      <td>AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 9</td>\n",
       "      <td>[CHAIN, 4141, 4253, Non-structural protein 9, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4141</td>\n",
       "      <td>4253</td>\n",
       "      <td>Non-structural protein 9</td>\n",
       "      <td>uniprot.chain:PRO_0000449643</td>\n",
       "      <td>NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLS...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 10</td>\n",
       "      <td>[CHAIN, 4254, 4392, Non-structural protein 10,...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4254</td>\n",
       "      <td>4392</td>\n",
       "      <td>Non-structural protein 10</td>\n",
       "      <td>uniprot.chain:PRO_0000449644</td>\n",
       "      <td>AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLC...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 11</td>\n",
       "      <td>[CHAIN, 4393, 4405, Non-structural protein 11,...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4393</td>\n",
       "      <td>4405</td>\n",
       "      <td>Non-structural protein 11</td>\n",
       "      <td>uniprot.chain:PRO_0000449645</td>\n",
       "      <td>SADAQSFLNGFAV</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>P0DTD3</td>\n",
       "      <td>Y14_SARS2</td>\n",
       "      <td>MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...</td>\n",
       "      <td>73</td>\n",
       "      <td>Uncharacterized protein 14 (ORF14)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..73;  /note=\"Uncharacterized protein 1...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>Uncharacterized protein 14;ORF14</td>\n",
       "      <td>[CHAIN, 1, 73, Uncharacterized protein 14, uni...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>73</td>\n",
       "      <td>Uncharacterized protein 14</td>\n",
       "      <td>uniprot.chain:PRO_0000449658</td>\n",
       "      <td>MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>P0DTC4</td>\n",
       "      <td>VEMP_SARS2</td>\n",
       "      <td>MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein (E) (sM protein)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..75;  /note=\"Envelope small membrane p...</td>\n",
       "      <td></td>\n",
       "      <td>pore formation by virus in membrane of host ce...</td>\n",
       "      <td>True</td>\n",
       "      <td>Envelope small membrane protein;E;sM protein</td>\n",
       "      <td>[CHAIN, 1, 75, Envelope small membrane protein...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449651</td>\n",
       "      <td>MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein;S glycoprotein;E2;Peplomer ...</td>\n",
       "      <td>[PROTEIN, 1, 1273, Spike glycoprotein , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein</td>\n",
       "      <td></td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike glycoprotein</td>\n",
       "      <td>[CHAIN, 13, 1273, Spike glycoprotein, uniprot....</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>13</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein</td>\n",
       "      <td>uniprot.chain:PRO_0000449646</td>\n",
       "      <td>SQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPF...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike protein S1</td>\n",
       "      <td>[CHAIN, 13, 685, Spike protein S1, uniprot.cha...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>13</td>\n",
       "      <td>685</td>\n",
       "      <td>Spike protein S1</td>\n",
       "      <td>uniprot.chain:PRO_0000449647</td>\n",
       "      <td>SQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPF...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike protein S2</td>\n",
       "      <td>[CHAIN, 686, 1273, Spike protein S2, uniprot.c...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>686</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike protein S2</td>\n",
       "      <td>uniprot.chain:PRO_0000449648</td>\n",
       "      <td>SVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSM...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>P0DTC2</td>\n",
       "      <td>SPIKE_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike glycoprotein (S glycoprotein) (E2) (Pepl...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...</td>\n",
       "      <td></td>\n",
       "      <td>endocytosis involved in viral entry into host ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Spike protein S2'</td>\n",
       "      <td>[CHAIN, 816, 1273, Spike protein S2', uniprot....</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>816</td>\n",
       "      <td>1273</td>\n",
       "      <td>Spike protein S2'</td>\n",
       "      <td>uniprot.chain:PRO_0000449649</td>\n",
       "      <td>SFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVL...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>P0DTC9</td>\n",
       "      <td>NCAP_SARS2</td>\n",
       "      <td>MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLP...</td>\n",
       "      <td>419</td>\n",
       "      <td>Nucleoprotein (N) (Nucleocapsid protein) (NC) ...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..419;  /note=\"Nucleoprotein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>Nucleoprotein;N;Nucleocapsid protein;NC;Protein N</td>\n",
       "      <td>[CHAIN, 1, 419, Nucleoprotein, uniprot.chain:P...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>419</td>\n",
       "      <td>Nucleoprotein</td>\n",
       "      <td>uniprot.chain:PRO_0000449656</td>\n",
       "      <td>MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLP...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>P0DTC8</td>\n",
       "      <td>NS8_SARS2</td>\n",
       "      <td>MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein (ORF8) (Non-structural protein 8)...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>ORF8 protein;ORF8;Non-structural protein 8;ns8</td>\n",
       "      <td>[PROTEIN, 1, 121, ORF8 protein , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein</td>\n",
       "      <td></td>\n",
       "      <td>MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>P0DTC8</td>\n",
       "      <td>NS8_SARS2</td>\n",
       "      <td>MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein (ORF8) (Non-structural protein 8)...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>ORF8 protein</td>\n",
       "      <td>[CHAIN, 16, 121, ORF8 protein, uniprot.chain:P...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>16</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF8 protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449655</td>\n",
       "      <td>FHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELC...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>P0DTD8</td>\n",
       "      <td>NS7B_SARS2</td>\n",
       "      <td>MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA</td>\n",
       "      <td>43</td>\n",
       "      <td>ORF7b protein (ORF7b) (Accessory protein 7b)</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..43;  /note=\"ORF7b protein\";  /id=\"PRO...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>True</td>\n",
       "      <td>ORF7b protein;ORF7b;Accessory protein 7b</td>\n",
       "      <td>[CHAIN, 1, 43, ORF7b protein, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>43</td>\n",
       "      <td>ORF7b protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449799</td>\n",
       "      <td>MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>P0DTC7</td>\n",
       "      <td>NS7A_SARS2</td>\n",
       "      <td>MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein (ORF7a) (Accessory protein 7a) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...</td>\n",
       "      <td></td>\n",
       "      <td>modulation by virus of host G0/G1 transition c...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF7a protein;ORF7a;Accessory protein 7a;Prote...</td>\n",
       "      <td>[PROTEIN, 1, 121, ORF7a protein , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein</td>\n",
       "      <td></td>\n",
       "      <td>MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>P0DTC7</td>\n",
       "      <td>NS7A_SARS2</td>\n",
       "      <td>MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein (ORF7a) (Accessory protein 7a) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...</td>\n",
       "      <td></td>\n",
       "      <td>modulation by virus of host G0/G1 transition c...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF7a protein</td>\n",
       "      <td>[CHAIN, 16, 121, ORF7a protein, uniprot.chain:...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>16</td>\n",
       "      <td>121</td>\n",
       "      <td>ORF7a protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449654</td>\n",
       "      <td>ELYHYQECVRGTTVLLKEPCSSGTYEGNSPFHPLADNKFALTCFST...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>P0DTD2</td>\n",
       "      <td>ORF9B_SARS2</td>\n",
       "      <td>MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIIL...</td>\n",
       "      <td>97</td>\n",
       "      <td>ORF9b protein (ORF9b) (Accessory protein 9b) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..97;  /note=\"ORF9b protein\";  /evidenc...</td>\n",
       "      <td></td>\n",
       "      <td>suppression by virus of host MAVS activity [GO...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF9b protein;ORF9b;Accessory protein 9b;ORF-9...</td>\n",
       "      <td>[CHAIN, 1, 97, ORF9b protein, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>97</td>\n",
       "      <td>ORF9b protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449657</td>\n",
       "      <td>MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIIL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...</td>\n",
       "      <td>[CHAIN, 1, 7096, Replicase polyprotein 1ab, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab</td>\n",
       "      <td>uniprot.chain:PRO_0000449618</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>[CHAIN, 1, 180, Host translation inhibitor nsp...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>180</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>uniprot.chain:PRO_0000449619</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>[CHAIN, 181, 818, Non-structural protein 2, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>181</td>\n",
       "      <td>818</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>uniprot.chain:PRO_0000449620</td>\n",
       "      <td>AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKR...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>[CHAIN, 819, 2763, Non-structural protein 3, u...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>819</td>\n",
       "      <td>2763</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>uniprot.chain:PRO_0000449621</td>\n",
       "      <td>APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVEL...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 4</td>\n",
       "      <td>[CHAIN, 2764, 3263, Non-structural protein 4, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>2764</td>\n",
       "      <td>3263</td>\n",
       "      <td>Non-structural protein 4</td>\n",
       "      <td>uniprot.chain:PRO_0000449622</td>\n",
       "      <td>KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td>[CHAIN, 3264, 3569, 3C-like proteinase, unipro...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3264</td>\n",
       "      <td>3569</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td>uniprot.chain:PRO_0000449623</td>\n",
       "      <td>SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 6</td>\n",
       "      <td>[CHAIN, 3570, 3859, Non-structural protein 6, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3570</td>\n",
       "      <td>3859</td>\n",
       "      <td>Non-structural protein 6</td>\n",
       "      <td>uniprot.chain:PRO_0000449624</td>\n",
       "      <td>SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFA...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 7</td>\n",
       "      <td>[CHAIN, 3860, 3942, Non-structural protein 7, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3860</td>\n",
       "      <td>3942</td>\n",
       "      <td>Non-structural protein 7</td>\n",
       "      <td>uniprot.chain:PRO_0000449625</td>\n",
       "      <td>SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTT...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 8</td>\n",
       "      <td>[CHAIN, 3943, 4140, Non-structural protein 8, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>3943</td>\n",
       "      <td>4140</td>\n",
       "      <td>Non-structural protein 8</td>\n",
       "      <td>uniprot.chain:PRO_0000449626</td>\n",
       "      <td>AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 9</td>\n",
       "      <td>[CHAIN, 4141, 4253, Non-structural protein 9, ...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4141</td>\n",
       "      <td>4253</td>\n",
       "      <td>Non-structural protein 9</td>\n",
       "      <td>uniprot.chain:PRO_0000449627</td>\n",
       "      <td>NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLS...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 10</td>\n",
       "      <td>[CHAIN, 4254, 4392, Non-structural protein 10,...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4254</td>\n",
       "      <td>4392</td>\n",
       "      <td>Non-structural protein 10</td>\n",
       "      <td>uniprot.chain:PRO_0000449628</td>\n",
       "      <td>AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLC...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>RNA-directed RNA polymerase</td>\n",
       "      <td>[CHAIN, 4393, 5324, RNA-directed RNA polymeras...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>4393</td>\n",
       "      <td>5324</td>\n",
       "      <td>RNA-directed RNA polymerase</td>\n",
       "      <td>uniprot.chain:PRO_0000449629</td>\n",
       "      <td>SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFA...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Helicase</td>\n",
       "      <td>[CHAIN, 5325, 5925, Helicase, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>5325</td>\n",
       "      <td>5925</td>\n",
       "      <td>Helicase</td>\n",
       "      <td>uniprot.chain:PRO_0000449630</td>\n",
       "      <td>AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVN...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Proofreading exoribonuclease</td>\n",
       "      <td>[CHAIN, 5926, 6452, Proofreading exoribonuclea...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>5926</td>\n",
       "      <td>6452</td>\n",
       "      <td>Proofreading exoribonuclease</td>\n",
       "      <td>uniprot.chain:PRO_0000449631</td>\n",
       "      <td>AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Uridylate-specific endoribonuclease</td>\n",
       "      <td>[CHAIN, 6453, 6798, Uridylate-specific endorib...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>6453</td>\n",
       "      <td>6798</td>\n",
       "      <td>Uridylate-specific endoribonuclease</td>\n",
       "      <td>uniprot.chain:PRO_0000449632</td>\n",
       "      <td>SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENK...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P0DTD1</td>\n",
       "      <td>R1AB_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>7096</td>\n",
       "      <td>Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..7096;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>2'-O-methyltransferase</td>\n",
       "      <td>[CHAIN, 6799, 7096, 2'-O-methyltransferase, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>6799</td>\n",
       "      <td>7096</td>\n",
       "      <td>2'-O-methyltransferase</td>\n",
       "      <td>uniprot.chain:PRO_0000449633</td>\n",
       "      <td>SSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAK...</td>\n",
       "      <td>False</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>P0DTC3</td>\n",
       "      <td>AP3A_SARS2</td>\n",
       "      <td>MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWL...</td>\n",
       "      <td>275</td>\n",
       "      <td>ORF3a protein (ORF3a) (Accessory protein 3a) (...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..275;  /note=\"ORF3a protein\";  /id=\"PR...</td>\n",
       "      <td></td>\n",
       "      <td>pore formation by virus in membrane of host ce...</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF3a protein;ORF3a;Accessory protein 3a;Prote...</td>\n",
       "      <td>[CHAIN, 1, 275, ORF3a protein, uniprot.chain:P...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>275</td>\n",
       "      <td>ORF3a protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449650</td>\n",
       "      <td>MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>P0DTC6</td>\n",
       "      <td>NS6_SARS2</td>\n",
       "      <td>MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTE...</td>\n",
       "      <td>61</td>\n",
       "      <td>ORF6 protein (ORF6) (Accessory protein 6) (Non...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td>CHAIN 1..61;  /note=\"ORF6 protein\";  /id=\"PRO_...</td>\n",
       "      <td></td>\n",
       "      <td>pathogenesis [GO:0009405]</td>\n",
       "      <td>True</td>\n",
       "      <td>ORF6 protein;ORF6;Accessory protein 6;Non-stru...</td>\n",
       "      <td>[CHAIN, 1, 61, ORF6 protein, uniprot.chain:PRO...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>61</td>\n",
       "      <td>ORF6 protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449653</td>\n",
       "      <td>MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTE...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>A0A7D4BMC0</td>\n",
       "      <td>A0A7D4BMC0_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>ORF1a polyprotein</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>ORF1a polyprotein</td>\n",
       "      <td>[PROTEIN, 1, 4405, ORF1a polyprotein, ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>ORF1a polyprotein</td>\n",
       "      <td></td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>A0A6M6J105</td>\n",
       "      <td>A0A6M6J105_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>3C-like proteinase (EC 3.4.19.12) (EC 3.4.22.6...</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>3C-like proteinase;EC 3.4.19.12;EC 3.4.22.69;G...</td>\n",
       "      <td>[PROTEIN, 1, 4405, 3C-like proteinase , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>3C-like proteinase</td>\n",
       "      <td></td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>A0A6H0JIU7</td>\n",
       "      <td>A0A6H0JIU7_SARS2</td>\n",
       "      <td>MIELSLIDFYLCXLAFLLFLVLIMLIIFWFSLELQDHNETCHA</td>\n",
       "      <td>43</td>\n",
       "      <td>Accessory protein 7b</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>Accessory protein 7b</td>\n",
       "      <td>[PROTEIN, 1, 43, Accessory protein 7b, ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>43</td>\n",
       "      <td>Accessory protein 7b</td>\n",
       "      <td></td>\n",
       "      <td>MIELSLIDFYLCXLAFLLFLVLIMLIIFWFSLELQDHNETCHA</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>A0A6M4N1G6</td>\n",
       "      <td>A0A6M4N1G6_SARS2</td>\n",
       "      <td>MYSFVSEETGTLIXNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein (E protein) (s...</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>Envelope small membrane protein;E protein;sM p...</td>\n",
       "      <td>[PROTEIN, 1, 75, Envelope small membrane prote...</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>75</td>\n",
       "      <td>Envelope small membrane protein</td>\n",
       "      <td></td>\n",
       "      <td>MYSFVSEETGTLIXNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>A0A7D7KXN3</td>\n",
       "      <td>A0A7D7KXN3_SARS2</td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>1273</td>\n",
       "      <td>Surface glycoprotein</td>\n",
       "      <td>unreviewed</td>\n",
       "      <td>2697049</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>False</td>\n",
       "      <td>Surface glycoprotein</td>\n",
       "      <td>[PROTEIN, 1, 1273, Surface glycoprotein, ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>1273</td>\n",
       "      <td>Surface glycoprotein</td>\n",
       "      <td></td>\n",
       "      <td>MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...</td>\n",
       "      <td>True</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "         Entry        Entry name  \\\n",
       "0       P0DTC5        VME1_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "1       P0DTC1         R1A_SARS2   \n",
       "2       P0DTD3         Y14_SARS2   \n",
       "3       P0DTC4        VEMP_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "4       P0DTC2       SPIKE_SARS2   \n",
       "5       P0DTC9        NCAP_SARS2   \n",
       "6       P0DTC8         NS8_SARS2   \n",
       "6       P0DTC8         NS8_SARS2   \n",
       "7       P0DTD8        NS7B_SARS2   \n",
       "8       P0DTC7        NS7A_SARS2   \n",
       "8       P0DTC7        NS7A_SARS2   \n",
       "9       P0DTD2       ORF9B_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "10      P0DTD1        R1AB_SARS2   \n",
       "11      P0DTC3        AP3A_SARS2   \n",
       "12      P0DTC6         NS6_SARS2   \n",
       "13  A0A7D4BMC0  A0A7D4BMC0_SARS2   \n",
       "14  A0A6M6J105  A0A6M6J105_SARS2   \n",
       "15  A0A6H0JIU7  A0A6H0JIU7_SARS2   \n",
       "16  A0A6M4N1G6  A0A6M4N1G6_SARS2   \n",
       "17  A0A7D7KXN3  A0A7D7KXN3_SARS2   \n",
       "\n",
       "                                             Sequence Length  \\\n",
       "0   MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...    222   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "2   MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...     73   \n",
       "3   MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...     75   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "5   MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLP...    419   \n",
       "6   MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...    121   \n",
       "6   MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...    121   \n",
       "7         MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA     43   \n",
       "8   MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...    121   \n",
       "8   MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...    121   \n",
       "9   MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIIL...     97   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   7096   \n",
       "11  MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWL...    275   \n",
       "12  MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTE...     61   \n",
       "13  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "14  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "15        MIELSLIDFYLCXLAFLLFLVLIMLIIFWFSLELQDHNETCHA     43   \n",
       "16  MYSFVSEETGTLIXNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...     75   \n",
       "17  MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...   1273   \n",
       "\n",
       "                                        Protein names      Status Organism ID  \\\n",
       "0   Membrane protein (M) (E1 glycoprotein) (Matrix...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "1   Replicase polyprotein 1a (pp1a) (ORF1a polypro...    reviewed     2697049   \n",
       "2                  Uncharacterized protein 14 (ORF14)    reviewed     2697049   \n",
       "3    Envelope small membrane protein (E) (sM protein)    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "4   Spike glycoprotein (S glycoprotein) (E2) (Pepl...    reviewed     2697049   \n",
       "5   Nucleoprotein (N) (Nucleocapsid protein) (NC) ...    reviewed     2697049   \n",
       "6   ORF8 protein (ORF8) (Non-structural protein 8)...    reviewed     2697049   \n",
       "6   ORF8 protein (ORF8) (Non-structural protein 8)...    reviewed     2697049   \n",
       "7        ORF7b protein (ORF7b) (Accessory protein 7b)    reviewed     2697049   \n",
       "8   ORF7a protein (ORF7a) (Accessory protein 7a) (...    reviewed     2697049   \n",
       "8   ORF7a protein (ORF7a) (Accessory protein 7a) (...    reviewed     2697049   \n",
       "9   ORF9b protein (ORF9b) (Accessory protein 9b) (...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "10  Replicase polyprotein 1ab (pp1ab) (ORF1ab poly...    reviewed     2697049   \n",
       "11  ORF3a protein (ORF3a) (Accessory protein 3a) (...    reviewed     2697049   \n",
       "12  ORF6 protein (ORF6) (Accessory protein 6) (Non...    reviewed     2697049   \n",
       "13                                  ORF1a polyprotein  unreviewed     2697049   \n",
       "14  3C-like proteinase (EC 3.4.19.12) (EC 3.4.22.6...  unreviewed     2697049   \n",
       "15                               Accessory protein 7b  unreviewed     2697049   \n",
       "16  Envelope small membrane protein (E protein) (s...  unreviewed     2697049   \n",
       "17                               Surface glycoprotein  unreviewed     2697049   \n",
       "\n",
       "                                                Chain Peptide  \\\n",
       "0   CHAIN 1..222;  /note=\"Membrane protein\";  /id=...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "1   CHAIN 1..4405;  /note=\"Replicase polyprotein 1...           \n",
       "2   CHAIN 1..73;  /note=\"Uncharacterized protein 1...           \n",
       "3   CHAIN 1..75;  /note=\"Envelope small membrane p...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "4   CHAIN 13..1273;  /note=\"Spike glycoprotein\";  ...           \n",
       "5   CHAIN 1..419;  /note=\"Nucleoprotein\";  /id=\"PR...           \n",
       "6   CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...           \n",
       "6   CHAIN 16..121;  /note=\"ORF8 protein\";  /id=\"PR...           \n",
       "7   CHAIN 1..43;  /note=\"ORF7b protein\";  /id=\"PRO...           \n",
       "8   CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...           \n",
       "8   CHAIN 16..121;  /note=\"ORF7a protein\";  /evide...           \n",
       "9   CHAIN 1..97;  /note=\"ORF9b protein\";  /evidenc...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "10  CHAIN 1..7096;  /note=\"Replicase polyprotein 1...           \n",
       "11  CHAIN 1..275;  /note=\"ORF3a protein\";  /id=\"PR...           \n",
       "12  CHAIN 1..61;  /note=\"ORF6 protein\";  /id=\"PRO_...           \n",
       "13                                                              \n",
       "14                                                              \n",
       "15                                                              \n",
       "16                                                              \n",
       "17                                                              \n",
       "\n",
       "                   Gene ontology (biological process) reviewed  \\\n",
       "0   mitigation of host immune response by virus [G...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "1   induction by virus of catabolism of host mRNA ...     True   \n",
       "2                                                         True   \n",
       "3   pore formation by virus in membrane of host ce...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "4   endocytosis involved in viral entry into host ...     True   \n",
       "5                                                         True   \n",
       "6                                                         True   \n",
       "6                                                         True   \n",
       "7                                                         True   \n",
       "8   modulation by virus of host G0/G1 transition c...     True   \n",
       "8   modulation by virus of host G0/G1 transition c...     True   \n",
       "9   suppression by virus of host MAVS activity [GO...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "10  induction by virus of catabolism of host mRNA ...     True   \n",
       "11  pore formation by virus in membrane of host ce...     True   \n",
       "12                          pathogenesis [GO:0009405]     True   \n",
       "13                                                       False   \n",
       "14                                                       False   \n",
       "15                                                       False   \n",
       "16                                                       False   \n",
       "17                                                       False   \n",
       "\n",
       "                                            synonymes  \\\n",
       "0   Membrane protein;M;E1 glycoprotein;Matrix glyc...   \n",
       "1     Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1                     Host translation inhibitor nsp1   \n",
       "1                            Non-structural protein 2   \n",
       "1                            Non-structural protein 3   \n",
       "1                            Non-structural protein 4   \n",
       "1                                  3C-like proteinase   \n",
       "1                            Non-structural protein 6   \n",
       "1                            Non-structural protein 7   \n",
       "1                            Non-structural protein 8   \n",
       "1                            Non-structural protein 9   \n",
       "1                           Non-structural protein 10   \n",
       "1                           Non-structural protein 11   \n",
       "2                    Uncharacterized protein 14;ORF14   \n",
       "3        Envelope small membrane protein;E;sM protein   \n",
       "4   Spike glycoprotein;S glycoprotein;E2;Peplomer ...   \n",
       "4                                  Spike glycoprotein   \n",
       "4                                    Spike protein S1   \n",
       "4                                    Spike protein S2   \n",
       "4                                   Spike protein S2'   \n",
       "5   Nucleoprotein;N;Nucleocapsid protein;NC;Protein N   \n",
       "6      ORF8 protein;ORF8;Non-structural protein 8;ns8   \n",
       "6                                        ORF8 protein   \n",
       "7            ORF7b protein;ORF7b;Accessory protein 7b   \n",
       "8   ORF7a protein;ORF7a;Accessory protein 7a;Prote...   \n",
       "8                                       ORF7a protein   \n",
       "9   ORF9b protein;ORF9b;Accessory protein 9b;ORF-9...   \n",
       "10  Replicase polyprotein 1ab;pp1ab;ORF1ab polypro...   \n",
       "10                    Host translation inhibitor nsp1   \n",
       "10                           Non-structural protein 2   \n",
       "10                           Non-structural protein 3   \n",
       "10                           Non-structural protein 4   \n",
       "10                                 3C-like proteinase   \n",
       "10                           Non-structural protein 6   \n",
       "10                           Non-structural protein 7   \n",
       "10                           Non-structural protein 8   \n",
       "10                           Non-structural protein 9   \n",
       "10                          Non-structural protein 10   \n",
       "10                        RNA-directed RNA polymerase   \n",
       "10                                           Helicase   \n",
       "10                       Proofreading exoribonuclease   \n",
       "10                Uridylate-specific endoribonuclease   \n",
       "10                             2'-O-methyltransferase   \n",
       "11  ORF3a protein;ORF3a;Accessory protein 3a;Prote...   \n",
       "12  ORF6 protein;ORF6;Accessory protein 6;Non-stru...   \n",
       "13                                  ORF1a polyprotein   \n",
       "14  3C-like proteinase;EC 3.4.19.12;EC 3.4.22.69;G...   \n",
       "15                               Accessory protein 7b   \n",
       "16  Envelope small membrane protein;E protein;sM p...   \n",
       "17                               Surface glycoprotein   \n",
       "\n",
       "                                             Features     type start   end  \\\n",
       "0   [CHAIN, 1, 222, Membrane protein, uniprot.chai...    CHAIN     1   222   \n",
       "1   [CHAIN, 1, 4405, Replicase polyprotein 1a, uni...    CHAIN     1  4405   \n",
       "1   [CHAIN, 1, 180, Host translation inhibitor nsp...    CHAIN     1   180   \n",
       "1   [CHAIN, 181, 818, Non-structural protein 2, un...    CHAIN   181   818   \n",
       "1   [CHAIN, 819, 2763, Non-structural protein 3, u...    CHAIN   819  2763   \n",
       "1   [CHAIN, 2764, 3263, Non-structural protein 4, ...    CHAIN  2764  3263   \n",
       "1   [CHAIN, 3264, 3569, 3C-like proteinase, unipro...    CHAIN  3264  3569   \n",
       "1   [CHAIN, 3570, 3859, Non-structural protein 6, ...    CHAIN  3570  3859   \n",
       "1   [CHAIN, 3860, 3942, Non-structural protein 7, ...    CHAIN  3860  3942   \n",
       "1   [CHAIN, 3943, 4140, Non-structural protein 8, ...    CHAIN  3943  4140   \n",
       "1   [CHAIN, 4141, 4253, Non-structural protein 9, ...    CHAIN  4141  4253   \n",
       "1   [CHAIN, 4254, 4392, Non-structural protein 10,...    CHAIN  4254  4392   \n",
       "1   [CHAIN, 4393, 4405, Non-structural protein 11,...    CHAIN  4393  4405   \n",
       "2   [CHAIN, 1, 73, Uncharacterized protein 14, uni...    CHAIN     1    73   \n",
       "3   [CHAIN, 1, 75, Envelope small membrane protein...    CHAIN     1    75   \n",
       "4           [PROTEIN, 1, 1273, Spike glycoprotein , ]  PROTEIN     1  1273   \n",
       "4   [CHAIN, 13, 1273, Spike glycoprotein, uniprot....    CHAIN    13  1273   \n",
       "4   [CHAIN, 13, 685, Spike protein S1, uniprot.cha...    CHAIN    13   685   \n",
       "4   [CHAIN, 686, 1273, Spike protein S2, uniprot.c...    CHAIN   686  1273   \n",
       "4   [CHAIN, 816, 1273, Spike protein S2', uniprot....    CHAIN   816  1273   \n",
       "5   [CHAIN, 1, 419, Nucleoprotein, uniprot.chain:P...    CHAIN     1   419   \n",
       "6                  [PROTEIN, 1, 121, ORF8 protein , ]  PROTEIN     1   121   \n",
       "6   [CHAIN, 16, 121, ORF8 protein, uniprot.chain:P...    CHAIN    16   121   \n",
       "7   [CHAIN, 1, 43, ORF7b protein, uniprot.chain:PR...    CHAIN     1    43   \n",
       "8                 [PROTEIN, 1, 121, ORF7a protein , ]  PROTEIN     1   121   \n",
       "8   [CHAIN, 16, 121, ORF7a protein, uniprot.chain:...    CHAIN    16   121   \n",
       "9   [CHAIN, 1, 97, ORF9b protein, uniprot.chain:PR...    CHAIN     1    97   \n",
       "10  [CHAIN, 1, 7096, Replicase polyprotein 1ab, un...    CHAIN     1  7096   \n",
       "10  [CHAIN, 1, 180, Host translation inhibitor nsp...    CHAIN     1   180   \n",
       "10  [CHAIN, 181, 818, Non-structural protein 2, un...    CHAIN   181   818   \n",
       "10  [CHAIN, 819, 2763, Non-structural protein 3, u...    CHAIN   819  2763   \n",
       "10  [CHAIN, 2764, 3263, Non-structural protein 4, ...    CHAIN  2764  3263   \n",
       "10  [CHAIN, 3264, 3569, 3C-like proteinase, unipro...    CHAIN  3264  3569   \n",
       "10  [CHAIN, 3570, 3859, Non-structural protein 6, ...    CHAIN  3570  3859   \n",
       "10  [CHAIN, 3860, 3942, Non-structural protein 7, ...    CHAIN  3860  3942   \n",
       "10  [CHAIN, 3943, 4140, Non-structural protein 8, ...    CHAIN  3943  4140   \n",
       "10  [CHAIN, 4141, 4253, Non-structural protein 9, ...    CHAIN  4141  4253   \n",
       "10  [CHAIN, 4254, 4392, Non-structural protein 10,...    CHAIN  4254  4392   \n",
       "10  [CHAIN, 4393, 5324, RNA-directed RNA polymeras...    CHAIN  4393  5324   \n",
       "10  [CHAIN, 5325, 5925, Helicase, uniprot.chain:PR...    CHAIN  5325  5925   \n",
       "10  [CHAIN, 5926, 6452, Proofreading exoribonuclea...    CHAIN  5926  6452   \n",
       "10  [CHAIN, 6453, 6798, Uridylate-specific endorib...    CHAIN  6453  6798   \n",
       "10  [CHAIN, 6799, 7096, 2'-O-methyltransferase, un...    CHAIN  6799  7096   \n",
       "11  [CHAIN, 1, 275, ORF3a protein, uniprot.chain:P...    CHAIN     1   275   \n",
       "12  [CHAIN, 1, 61, ORF6 protein, uniprot.chain:PRO...    CHAIN     1    61   \n",
       "13            [PROTEIN, 1, 4405, ORF1a polyprotein, ]  PROTEIN     1  4405   \n",
       "14          [PROTEIN, 1, 4405, 3C-like proteinase , ]  PROTEIN     1  4405   \n",
       "15           [PROTEIN, 1, 43, Accessory protein 7b, ]  PROTEIN     1    43   \n",
       "16  [PROTEIN, 1, 75, Envelope small membrane prote...  PROTEIN     1    75   \n",
       "17         [PROTEIN, 1, 1273, Surface glycoprotein, ]  PROTEIN     1  1273   \n",
       "\n",
       "                                   name                         proId  \\\n",
       "0                      Membrane protein  uniprot.chain:PRO_0000449652   \n",
       "1              Replicase polyprotein 1a  uniprot.chain:PRO_0000449634   \n",
       "1       Host translation inhibitor nsp1  uniprot.chain:PRO_0000449635   \n",
       "1              Non-structural protein 2  uniprot.chain:PRO_0000449636   \n",
       "1              Non-structural protein 3  uniprot.chain:PRO_0000449637   \n",
       "1              Non-structural protein 4  uniprot.chain:PRO_0000449638   \n",
       "1                    3C-like proteinase  uniprot.chain:PRO_0000449639   \n",
       "1              Non-structural protein 6  uniprot.chain:PRO_0000449640   \n",
       "1              Non-structural protein 7  uniprot.chain:PRO_0000449641   \n",
       "1              Non-structural protein 8  uniprot.chain:PRO_0000449642   \n",
       "1              Non-structural protein 9  uniprot.chain:PRO_0000449643   \n",
       "1             Non-structural protein 10  uniprot.chain:PRO_0000449644   \n",
       "1             Non-structural protein 11  uniprot.chain:PRO_0000449645   \n",
       "2            Uncharacterized protein 14  uniprot.chain:PRO_0000449658   \n",
       "3       Envelope small membrane protein  uniprot.chain:PRO_0000449651   \n",
       "4                    Spike glycoprotein                                 \n",
       "4                    Spike glycoprotein  uniprot.chain:PRO_0000449646   \n",
       "4                      Spike protein S1  uniprot.chain:PRO_0000449647   \n",
       "4                      Spike protein S2  uniprot.chain:PRO_0000449648   \n",
       "4                     Spike protein S2'  uniprot.chain:PRO_0000449649   \n",
       "5                         Nucleoprotein  uniprot.chain:PRO_0000449656   \n",
       "6                          ORF8 protein                                 \n",
       "6                          ORF8 protein  uniprot.chain:PRO_0000449655   \n",
       "7                         ORF7b protein  uniprot.chain:PRO_0000449799   \n",
       "8                         ORF7a protein                                 \n",
       "8                         ORF7a protein  uniprot.chain:PRO_0000449654   \n",
       "9                         ORF9b protein  uniprot.chain:PRO_0000449657   \n",
       "10            Replicase polyprotein 1ab  uniprot.chain:PRO_0000449618   \n",
       "10      Host translation inhibitor nsp1  uniprot.chain:PRO_0000449619   \n",
       "10             Non-structural protein 2  uniprot.chain:PRO_0000449620   \n",
       "10             Non-structural protein 3  uniprot.chain:PRO_0000449621   \n",
       "10             Non-structural protein 4  uniprot.chain:PRO_0000449622   \n",
       "10                   3C-like proteinase  uniprot.chain:PRO_0000449623   \n",
       "10             Non-structural protein 6  uniprot.chain:PRO_0000449624   \n",
       "10             Non-structural protein 7  uniprot.chain:PRO_0000449625   \n",
       "10             Non-structural protein 8  uniprot.chain:PRO_0000449626   \n",
       "10             Non-structural protein 9  uniprot.chain:PRO_0000449627   \n",
       "10            Non-structural protein 10  uniprot.chain:PRO_0000449628   \n",
       "10          RNA-directed RNA polymerase  uniprot.chain:PRO_0000449629   \n",
       "10                             Helicase  uniprot.chain:PRO_0000449630   \n",
       "10         Proofreading exoribonuclease  uniprot.chain:PRO_0000449631   \n",
       "10  Uridylate-specific endoribonuclease  uniprot.chain:PRO_0000449632   \n",
       "10               2'-O-methyltransferase  uniprot.chain:PRO_0000449633   \n",
       "11                        ORF3a protein  uniprot.chain:PRO_0000449650   \n",
       "12                         ORF6 protein  uniprot.chain:PRO_0000449653   \n",
       "13                    ORF1a polyprotein                                 \n",
       "14                   3C-like proteinase                                 \n",
       "15                 Accessory protein 7b                                 \n",
       "16      Envelope small membrane protein                                 \n",
       "17                 Surface glycoprotein                                 \n",
       "\n",
       "                                             sequence  fullLength  \n",
       "0   MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...        True  \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...        True  \n",
       "1   MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...       False  \n",
       "1   AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKR...       False  \n",
       "1   APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVEL...       False  \n",
       "1   KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY...       False  \n",
       "1   SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS...       False  \n",
       "1   SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFA...       False  \n",
       "1   SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTT...       False  \n",
       "1   AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK...       False  \n",
       "1   NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLS...       False  \n",
       "1   AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLC...       False  \n",
       "1                                       SADAQSFLNGFAV       False  \n",
       "2   MLQSCYNFLKEQHCQKASTQKGAEAAVKPLLVPHHVVATVQEIQLQ...        True  \n",
       "3   MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...        True  \n",
       "4   MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...        True  \n",
       "4   SQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPF...       False  \n",
       "4   SQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPF...       False  \n",
       "4   SVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSM...       False  \n",
       "4   SFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVL...       False  \n",
       "5   MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLP...        True  \n",
       "6   MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWY...        True  \n",
       "6   FHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELC...       False  \n",
       "7         MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA        True  \n",
       "8   MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPF...        True  \n",
       "8   ELYHYQECVRGTTVLLKEPCSSGTYEGNSPFHPLADNKFALTCFST...       False  \n",
       "9   MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIIL...        True  \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...        True  \n",
       "10  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...       False  \n",
       "10  AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKR...       False  \n",
       "10  APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVEL...       False  \n",
       "10  KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY...       False  \n",
       "10  SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS...       False  \n",
       "10  SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFA...       False  \n",
       "10  SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTT...       False  \n",
       "10  AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK...       False  \n",
       "10  NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLS...       False  \n",
       "10  AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLC...       False  \n",
       "10  SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFA...       False  \n",
       "10  AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVN...       False  \n",
       "10  AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP...       False  \n",
       "10  SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENK...       False  \n",
       "10  SSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAK...       False  \n",
       "11  MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWL...        True  \n",
       "12  MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTE...        True  \n",
       "13  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...        True  \n",
       "14  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...        True  \n",
       "15        MIELSLIDFYLCXLAFLLFLVLIMLIIFWFSLELQDHNETCHA        True  \n",
       "16  MYSFVSEETGTLIXNSVLLFLAFVVFLLVTLAILTALRLCAYCCNI...        True  \n",
       "17  MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSS...        True  "
      ]
     },
     "execution_count": 34,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.head(50)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp.rename(columns={'Organism ID': 'taxonomyId','Entry': 'accession', 'Entry name': 'entryName'}, inplace=True)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "##### Assign unique identifiers\n",
    "\n",
    "md5 hashcodes for the protein sequence and CURIEs for accession and taxonomyId"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 36,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['id'] = unp['sequence'].apply(lambda seq: 'md5:' + hashlib.md5(seq.encode()).hexdigest())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 37,
   "metadata": {},
   "outputs": [],
   "source": [
    "# disambiguate id by taxonomyId (same sequence for different organisms)\n",
    "unp['id'] = unp['id'] + '-' + unp['taxonomyId']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 38,
   "metadata": {},
   "outputs": [],
   "source": [
    "unp['accession'] = 'uniprot:' + unp['accession']\n",
    "unp['taxonomyId'] = 'taxonomy:' + unp['taxonomyId']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 39,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>accession</th>\n",
       "      <th>entryName</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>Length</th>\n",
       "      <th>Protein names</th>\n",
       "      <th>Status</th>\n",
       "      <th>taxonomyId</th>\n",
       "      <th>Chain</th>\n",
       "      <th>Peptide</th>\n",
       "      <th>Gene ontology (biological process)</th>\n",
       "      <th>reviewed</th>\n",
       "      <th>synonymes</th>\n",
       "      <th>Features</th>\n",
       "      <th>type</th>\n",
       "      <th>start</th>\n",
       "      <th>end</th>\n",
       "      <th>name</th>\n",
       "      <th>proId</th>\n",
       "      <th>sequence</th>\n",
       "      <th>fullLength</th>\n",
       "      <th>id</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Kininogen-1;Alpha-2-thiol proteinase inhibitor...</td>\n",
       "      <td>[PROTEIN, 1, 644, Kininogen-1 , ]</td>\n",
       "      <td>PROTEIN</td>\n",
       "      <td>1</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1</td>\n",
       "      <td></td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>True</td>\n",
       "      <td>md5:693c7762bf152c58e00ff05e19347899-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Kininogen-1</td>\n",
       "      <td>[CHAIN, 19, 644, Kininogen-1, uniprot.chain:PR...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>19</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1</td>\n",
       "      <td>uniprot.chain:PRO_0000006685</td>\n",
       "      <td>QESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATK...</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:7fce5e096d222db791e61728783862ef-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Kininogen-1 heavy chain</td>\n",
       "      <td>[CHAIN, 19, 380, Kininogen-1 heavy chain, unip...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>19</td>\n",
       "      <td>380</td>\n",
       "      <td>Kininogen-1 heavy chain</td>\n",
       "      <td>uniprot.chain:PRO_0000006686</td>\n",
       "      <td>QESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATK...</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:65df10fd1e958993a8df7cbc9eeaef49-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Kininogen-1 light chain</td>\n",
       "      <td>[CHAIN, 390, 644, Kininogen-1 light chain, uni...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>390</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 light chain</td>\n",
       "      <td>uniprot.chain:PRO_0000006689</td>\n",
       "      <td>SSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEK...</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:918354eb803d70a0af51f56240aa6918-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>T-kinin</td>\n",
       "      <td>[PEPTIDE, 376, 389, T-kinin, uniprot.chain:PRO...</td>\n",
       "      <td>PEPTIDE</td>\n",
       "      <td>376</td>\n",
       "      <td>389</td>\n",
       "      <td>T-kinin</td>\n",
       "      <td>uniprot.chain:PRO_0000372485</td>\n",
       "      <td>ISLMKRPPGFSPFR</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:7c3750d37b3f3520024958fdba8c0d46-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Lysyl-bradykinin</td>\n",
       "      <td>[PEPTIDE, 380, 389, Lysyl-bradykinin, uniprot....</td>\n",
       "      <td>PEPTIDE</td>\n",
       "      <td>380</td>\n",
       "      <td>389</td>\n",
       "      <td>Lysyl-bradykinin</td>\n",
       "      <td>uniprot.chain:PRO_0000006687</td>\n",
       "      <td>KRPPGFSPFR</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:33b2d4498a0558b6ae786d4a6d4620cd-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Bradykinin</td>\n",
       "      <td>[PEPTIDE, 381, 389, Bradykinin, uniprot.chain:...</td>\n",
       "      <td>PEPTIDE</td>\n",
       "      <td>381</td>\n",
       "      <td>389</td>\n",
       "      <td>Bradykinin</td>\n",
       "      <td>uniprot.chain:PRO_0000006688</td>\n",
       "      <td>RPPGFSPFR</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:c5a9e54cc23314d0f69ea9cca09ee617-9606</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37974</th>\n",
       "      <td>uniprot:P01042</td>\n",
       "      <td>KNG1_HUMAN</td>\n",
       "      <td>MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...</td>\n",
       "      <td>644</td>\n",
       "      <td>Kininogen-1 (Alpha-2-thiol proteinase inhibito...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:9606</td>\n",
       "      <td>CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...</td>\n",
       "      <td>PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...</td>\n",
       "      <td>antimicrobial humoral immune response mediated...</td>\n",
       "      <td>True</td>\n",
       "      <td>Low molecular weight growth-promoting factor</td>\n",
       "      <td>[PEPTIDE, 431, 434, Low molecular weight growt...</td>\n",
       "      <td>PEPTIDE</td>\n",
       "      <td>431</td>\n",
       "      <td>434</td>\n",
       "      <td>Low molecular weight growth-promoting factor</td>\n",
       "      <td>uniprot.chain:PRO_0000006690</td>\n",
       "      <td>WGHE</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:fd9ee00f93cbe5c7daef3a211f113b63-9606</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "            accession   entryName  \\\n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "37974  uniprot:P01042  KNG1_HUMAN   \n",
       "\n",
       "                                                Sequence Length  \\\n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...    644   \n",
       "\n",
       "                                           Protein names    Status  \\\n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "37974  Kininogen-1 (Alpha-2-thiol proteinase inhibito...  reviewed   \n",
       "\n",
       "          taxonomyId                                              Chain  \\\n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "37974  taxonomy:9606  CHAIN 19..644;  /note=\"Kininogen-1\";  /id=\"PRO...   \n",
       "\n",
       "                                                 Peptide  \\\n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "37974  PEPTIDE 376..389;  /note=\"T-kinin\";  /id=\"PRO_...   \n",
       "\n",
       "                      Gene ontology (biological process) reviewed  \\\n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "37974  antimicrobial humoral immune response mediated...     True   \n",
       "\n",
       "                                               synonymes  \\\n",
       "37974  Kininogen-1;Alpha-2-thiol proteinase inhibitor...   \n",
       "37974                                        Kininogen-1   \n",
       "37974                            Kininogen-1 heavy chain   \n",
       "37974                            Kininogen-1 light chain   \n",
       "37974                                            T-kinin   \n",
       "37974                                   Lysyl-bradykinin   \n",
       "37974                                         Bradykinin   \n",
       "37974       Low molecular weight growth-promoting factor   \n",
       "\n",
       "                                                Features     type start  end  \\\n",
       "37974                  [PROTEIN, 1, 644, Kininogen-1 , ]  PROTEIN     1  644   \n",
       "37974  [CHAIN, 19, 644, Kininogen-1, uniprot.chain:PR...    CHAIN    19  644   \n",
       "37974  [CHAIN, 19, 380, Kininogen-1 heavy chain, unip...    CHAIN    19  380   \n",
       "37974  [CHAIN, 390, 644, Kininogen-1 light chain, uni...    CHAIN   390  644   \n",
       "37974  [PEPTIDE, 376, 389, T-kinin, uniprot.chain:PRO...  PEPTIDE   376  389   \n",
       "37974  [PEPTIDE, 380, 389, Lysyl-bradykinin, uniprot....  PEPTIDE   380  389   \n",
       "37974  [PEPTIDE, 381, 389, Bradykinin, uniprot.chain:...  PEPTIDE   381  389   \n",
       "37974  [PEPTIDE, 431, 434, Low molecular weight growt...  PEPTIDE   431  434   \n",
       "\n",
       "                                               name  \\\n",
       "37974                                   Kininogen-1   \n",
       "37974                                   Kininogen-1   \n",
       "37974                       Kininogen-1 heavy chain   \n",
       "37974                       Kininogen-1 light chain   \n",
       "37974                                       T-kinin   \n",
       "37974                              Lysyl-bradykinin   \n",
       "37974                                    Bradykinin   \n",
       "37974  Low molecular weight growth-promoting factor   \n",
       "\n",
       "                              proId  \\\n",
       "37974                                 \n",
       "37974  uniprot.chain:PRO_0000006685   \n",
       "37974  uniprot.chain:PRO_0000006686   \n",
       "37974  uniprot.chain:PRO_0000006689   \n",
       "37974  uniprot.chain:PRO_0000372485   \n",
       "37974  uniprot.chain:PRO_0000006687   \n",
       "37974  uniprot.chain:PRO_0000006688   \n",
       "37974  uniprot.chain:PRO_0000006690   \n",
       "\n",
       "                                                sequence  fullLength  \\\n",
       "37974  MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNS...        True   \n",
       "37974  QESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATK...       False   \n",
       "37974  QESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATK...       False   \n",
       "37974  SSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEK...       False   \n",
       "37974                                     ISLMKRPPGFSPFR       False   \n",
       "37974                                         KRPPGFSPFR       False   \n",
       "37974                                          RPPGFSPFR       False   \n",
       "37974                                               WGHE       False   \n",
       "\n",
       "                                              id  \n",
       "37974  md5:693c7762bf152c58e00ff05e19347899-9606  \n",
       "37974  md5:7fce5e096d222db791e61728783862ef-9606  \n",
       "37974  md5:65df10fd1e958993a8df7cbc9eeaef49-9606  \n",
       "37974  md5:918354eb803d70a0af51f56240aa6918-9606  \n",
       "37974  md5:7c3750d37b3f3520024958fdba8c0d46-9606  \n",
       "37974  md5:33b2d4498a0558b6ae786d4a6d4620cd-9606  \n",
       "37974  md5:c5a9e54cc23314d0f69ea9cca09ee617-9606  \n",
       "37974  md5:fd9ee00f93cbe5c7daef3a211f113b63-9606  "
      ]
     },
     "execution_count": 39,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.query(\"accession == 'uniprot:P01042'\")"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Save proteins"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [],
   "source": [
    "columns = ['id', 'name', 'synonymes', 'accession', 'entryName', 'proId', 'taxonomyId','sequence', \n",
    "           'start', 'end', 'fullLength', 'reviewed']\n",
    "unp.to_csv(NEO4J_IMPORT / '01a-UniProtProtein.csv', columns=columns, index = False)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 44,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>accession</th>\n",
       "      <th>entryName</th>\n",
       "      <th>Sequence</th>\n",
       "      <th>Length</th>\n",
       "      <th>Protein names</th>\n",
       "      <th>Status</th>\n",
       "      <th>taxonomyId</th>\n",
       "      <th>Chain</th>\n",
       "      <th>Peptide</th>\n",
       "      <th>Gene ontology (biological process)</th>\n",
       "      <th>reviewed</th>\n",
       "      <th>synonymes</th>\n",
       "      <th>Features</th>\n",
       "      <th>type</th>\n",
       "      <th>start</th>\n",
       "      <th>end</th>\n",
       "      <th>name</th>\n",
       "      <th>proId</th>\n",
       "      <th>sequence</th>\n",
       "      <th>fullLength</th>\n",
       "      <th>id</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>uniprot:P0DTC5</td>\n",
       "      <td>VME1_SARS2</td>\n",
       "      <td>MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein (M) (E1 glycoprotein) (Matrix...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:2697049</td>\n",
       "      <td>CHAIN 1..222;  /note=\"Membrane protein\";  /id=...</td>\n",
       "      <td></td>\n",
       "      <td>mitigation of host immune response by virus [G...</td>\n",
       "      <td>True</td>\n",
       "      <td>Membrane protein;M;E1 glycoprotein;Matrix glyc...</td>\n",
       "      <td>[CHAIN, 1, 222, Membrane protein, uniprot.chai...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>222</td>\n",
       "      <td>Membrane protein</td>\n",
       "      <td>uniprot.chain:PRO_0000449652</td>\n",
       "      <td>MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...</td>\n",
       "      <td>True</td>\n",
       "      <td>md5:1cd6abff79ad3633e17582eb0e576539-2697049</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>uniprot:P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Replicase polyprotein 1a;pp1a;ORF1a polyprotein</td>\n",
       "      <td>[CHAIN, 1, 4405, Replicase polyprotein 1a, uni...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a</td>\n",
       "      <td>uniprot.chain:PRO_0000449634</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>True</td>\n",
       "      <td>md5:e781b58591b8dbdd15f84dcbdec82105-2697049</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>uniprot:P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>[CHAIN, 1, 180, Host translation inhibitor nsp...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>1</td>\n",
       "      <td>180</td>\n",
       "      <td>Host translation inhibitor nsp1</td>\n",
       "      <td>uniprot.chain:PRO_0000449635</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:5c2c364f44079728c451280435c4236a-2697049</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>uniprot:P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>[CHAIN, 181, 818, Non-structural protein 2, un...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>181</td>\n",
       "      <td>818</td>\n",
       "      <td>Non-structural protein 2</td>\n",
       "      <td>uniprot.chain:PRO_0000449636</td>\n",
       "      <td>AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKR...</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:073edb2349ddcd9a72ecd9f5c1dccdc4-2697049</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>uniprot:P0DTC1</td>\n",
       "      <td>R1A_SARS2</td>\n",
       "      <td>MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...</td>\n",
       "      <td>4405</td>\n",
       "      <td>Replicase polyprotein 1a (pp1a) (ORF1a polypro...</td>\n",
       "      <td>reviewed</td>\n",
       "      <td>taxonomy:2697049</td>\n",
       "      <td>CHAIN 1..4405;  /note=\"Replicase polyprotein 1...</td>\n",
       "      <td></td>\n",
       "      <td>induction by virus of catabolism of host mRNA ...</td>\n",
       "      <td>True</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>[CHAIN, 819, 2763, Non-structural protein 3, u...</td>\n",
       "      <td>CHAIN</td>\n",
       "      <td>819</td>\n",
       "      <td>2763</td>\n",
       "      <td>Non-structural protein 3</td>\n",
       "      <td>uniprot.chain:PRO_0000449637</td>\n",
       "      <td>APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVEL...</td>\n",
       "      <td>False</td>\n",
       "      <td>md5:73935ca55d0ab6130627210ef6743c39-2697049</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "        accession   entryName  \\\n",
       "0  uniprot:P0DTC5  VME1_SARS2   \n",
       "1  uniprot:P0DTC1   R1A_SARS2   \n",
       "1  uniprot:P0DTC1   R1A_SARS2   \n",
       "1  uniprot:P0DTC1   R1A_SARS2   \n",
       "1  uniprot:P0DTC1   R1A_SARS2   \n",
       "\n",
       "                                            Sequence Length  \\\n",
       "0  MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...    222   \n",
       "1  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "1  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...   4405   \n",
       "\n",
       "                                       Protein names    Status  \\\n",
       "0  Membrane protein (M) (E1 glycoprotein) (Matrix...  reviewed   \n",
       "1  Replicase polyprotein 1a (pp1a) (ORF1a polypro...  reviewed   \n",
       "1  Replicase polyprotein 1a (pp1a) (ORF1a polypro...  reviewed   \n",
       "1  Replicase polyprotein 1a (pp1a) (ORF1a polypro...  reviewed   \n",
       "1  Replicase polyprotein 1a (pp1a) (ORF1a polypro...  reviewed   \n",
       "\n",
       "         taxonomyId                                              Chain  \\\n",
       "0  taxonomy:2697049  CHAIN 1..222;  /note=\"Membrane protein\";  /id=...   \n",
       "1  taxonomy:2697049  CHAIN 1..4405;  /note=\"Replicase polyprotein 1...   \n",
       "1  taxonomy:2697049  CHAIN 1..4405;  /note=\"Replicase polyprotein 1...   \n",
       "1  taxonomy:2697049  CHAIN 1..4405;  /note=\"Replicase polyprotein 1...   \n",
       "1  taxonomy:2697049  CHAIN 1..4405;  /note=\"Replicase polyprotein 1...   \n",
       "\n",
       "  Peptide                 Gene ontology (biological process) reviewed  \\\n",
       "0          mitigation of host immune response by virus [G...     True   \n",
       "1          induction by virus of catabolism of host mRNA ...     True   \n",
       "1          induction by virus of catabolism of host mRNA ...     True   \n",
       "1          induction by virus of catabolism of host mRNA ...     True   \n",
       "1          induction by virus of catabolism of host mRNA ...     True   \n",
       "\n",
       "                                           synonymes  \\\n",
       "0  Membrane protein;M;E1 glycoprotein;Matrix glyc...   \n",
       "1    Replicase polyprotein 1a;pp1a;ORF1a polyprotein   \n",
       "1                    Host translation inhibitor nsp1   \n",
       "1                           Non-structural protein 2   \n",
       "1                           Non-structural protein 3   \n",
       "\n",
       "                                            Features   type start   end  \\\n",
       "0  [CHAIN, 1, 222, Membrane protein, uniprot.chai...  CHAIN     1   222   \n",
       "1  [CHAIN, 1, 4405, Replicase polyprotein 1a, uni...  CHAIN     1  4405   \n",
       "1  [CHAIN, 1, 180, Host translation inhibitor nsp...  CHAIN     1   180   \n",
       "1  [CHAIN, 181, 818, Non-structural protein 2, un...  CHAIN   181   818   \n",
       "1  [CHAIN, 819, 2763, Non-structural protein 3, u...  CHAIN   819  2763   \n",
       "\n",
       "                              name                         proId  \\\n",
       "0                 Membrane protein  uniprot.chain:PRO_0000449652   \n",
       "1         Replicase polyprotein 1a  uniprot.chain:PRO_0000449634   \n",
       "1  Host translation inhibitor nsp1  uniprot.chain:PRO_0000449635   \n",
       "1         Non-structural protein 2  uniprot.chain:PRO_0000449636   \n",
       "1         Non-structural protein 3  uniprot.chain:PRO_0000449637   \n",
       "\n",
       "                                            sequence  fullLength  \\\n",
       "0  MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFL...        True   \n",
       "1  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...        True   \n",
       "1  MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHL...       False   \n",
       "1  AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKR...       False   \n",
       "1  APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVEL...       False   \n",
       "\n",
       "                                             id  \n",
       "0  md5:1cd6abff79ad3633e17582eb0e576539-2697049  \n",
       "1  md5:e781b58591b8dbdd15f84dcbdec82105-2697049  \n",
       "1  md5:5c2c364f44079728c451280435c4236a-2697049  \n",
       "1  md5:073edb2349ddcd9a72ecd9f5c1dccdc4-2697049  \n",
       "1  md5:73935ca55d0ab6130627210ef6743c39-2697049  "
      ]
     },
     "execution_count": 44,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "unp.head()"
   ]
  }
 ],
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