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JN.1.39+S:F456L mostly misplaced under JN.1.16 (96 seqs, 10 countries, 3 with S:R346T, 5 with S:R346S) #2543

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aviczhl2 opened this issue Apr 1, 2024 · 5 comments

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@aviczhl2
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aviczhl2 commented Apr 1, 2024

From branch 11 of sars-cov-2-variants/lineage-proposals#1253

JN.1.39+T22928C(S:F456L)

GISAID query: G2782T,T22926C,T22928C,-T111C,-23601,-C1594T,-26873,-21034, -10369
No. of seqs: 43( Germany 2 China 1 Japan 1 USA 39(1 from Japan, 1 from Switzerland, 1 from UAE)

First: EPI_ISL_18695414, USA, 2023-12-16
Latest: EPI_ISL_19005864, Japan, 2024-3-13

Mostly misplace as JN.1.16+G2782T, as S:F456L(T22928C) is much more of a convergent mutation than G2782T this shall be JN.1.39+S:F456L(T22928C). Seqs placed on other branches are excluded, maybe recombs.

@AngieHinrichs @corneliusroemer

usher

image

@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (47 seqs, 9 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (43 seqs, 6 countries) Apr 1, 2024
@Mydtlwn
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Mydtlwn commented Apr 3, 2024

@corneliusroemer

@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (43 seqs, 6 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (49 seqs, 6 countries) Apr 7, 2024
@aviczhl2
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57, Canada,Australia

@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (49 seqs, 6 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (57 seqs, 8 countries) Apr 11, 2024
@aviczhl2
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68, Ireland

@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (57 seqs, 8 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (68 seqs, 9 countries) Apr 24, 2024
@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (68 seqs, 9 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (72 seqs, 9 countries) Apr 28, 2024
@FedeGueli
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it has now a FLiRS branch of 2
[JN.1.16> G2782T ] = JN.1.39 > S:F456L > S:R346S (A22600C), T25054C
Query: G2782T,T3565C,A22600C, T25054C

Screenshot 2024-05-01 alle 23 01 29 https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice2_genome_test_1b8fb_26cb10.json?c=userOrOld&label=id:node_11429162

Note that there is another likely misplaced JN.1.39 with S:S346S but this time it is anticipated by S:S31F and it chould not be the same lineage of the one found here even if there is Geographical contiguity (US):
https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_1cd44_2abef0.json?label=id:node_6934825
Screenshot 2024-05-01 alle 23 05 44
Screenshot 2024-05-01 alle 23 05 58

@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (72 seqs, 9 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (89 seqs, 9 countries) May 5, 2024
@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (89 seqs, 9 countries) JN.1.39+S:F456L mostly misplaced under JN.1.16 (89 seqs, 9 countries, 2 with S:R346T, 4 with S:R346S) May 5, 2024
@aviczhl2
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96, Singapore

@aviczhl2 aviczhl2 changed the title JN.1.39+S:F456L mostly misplaced under JN.1.16 (89 seqs, 9 countries, 2 with S:R346T, 4 with S:R346S) JN.1.39+S:F456L mostly misplaced under JN.1.16 (96 seqs, 10 countries, 3 with S:R346T, 5 with S:R346S) May 10, 2024
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