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Welcome to the ldsc
wiki. This is the main repository for LD Score documentation. If you're just starting to use LD Score, the tutorials on LD Scores, heritability, genetic correlation and the LD Score regression intercept and [[partitioned h2|Partitioned Heritability]] describe how to run ldsc
. The FAQ answers several common questions about ldsc
output.
Note: Summary statistics from linear mixed models cannot be used to estimate SNP-heritability, but they can be used for estimating genetic correlation and partitioned heritability. This is because they have an "effective sample size" which differs from the true sample size; this affects SNP-heritability estimates but cancels out in the estimation of genetic correlation or proportion of heritability.