Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

Sign up for GitHub

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Jump to bottom

rg with sample overlap #419

Open
Cui4399 opened this issue Mar 4, 2024 · 1 comment
Open

rg with sample overlap #419

Cui4399 opened this issue Mar 4, 2024 · 1 comment

Comments

@Cui4399
Copy link

Cui4399 commented Mar 4, 2024

I want to run rg with two GWAS summary statistics, both derived from Finngen. Should I make some additional restrictions to correct sample overlap?
@aksarkar
Copy link

aksarkar commented May 8, 2024

@Cui4399 The intercept term of genetic correlation absorbs residual confounding, sample overlap, and phenotypic correlation. You do not need to perform additional steps to fit the model.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Assignees
No one assigned
Labels
None yet
Projects
None yet
Milestone
No milestone
Development

No branches or pull requests
2 participants
@aksarkar @Cui4399