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ConvertAllele and Variant normalization #19
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Hi Mo, Thank you for your interest in our tool. BayesTyper does not support translocations and these will therefore always to filtered by Regarding the normalization it sounds like either you are running on a vcf still containing symbolic alleles (like <INS> or <DEL>) or that your sequences in the file contains nucleotides that are not A, C, G, T or N. Please let me know if you have any other questions. Best, Jonas |
Thank you for your quick reply Jonas, I very much appreciate it. I just have a few more questions:
Thanks again, |
Hi, Sorry for the delayed reply.
Please let me know if you have any other questions. Best, Jonas |
Hi,
Firstly thank you for creating such a great resource. I have two questions (using v1.5):
bayesTyperTools convertAllele
almost 20% of variants are skipped, for example:In your new version I understand that there is added support for insertions, is there a way to rescue these skipped insertions?
bcftools norm
a significant number of variants suffer from errors and are not normalized, for example:Do you have any recommendations for this? I tried the
bcftools norm --check-ref ws
to fix 'bad sites'.Best wishes,
Mo
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