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Come up with source organism description for each genome #191

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taltman opened this issue Jul 10, 2020 · 4 comments
Open

Come up with source organism description for each genome #191

taltman opened this issue Jul 10, 2020 · 4 comments
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@taltman
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taltman commented Jul 10, 2020

Here's what NCBI has to say about assigning a meaningful entry for the "source" of the sequence material in the face of uncertainty:

https://www.ncbi.nlm.nih.gov/books/NBK53701/#gbankquickstart.can_i_use_the_word__unkn

So we need to come up with an organism descriptor for our submissions that don't need to be placed precisely in the NCBI Taxonomy DB, but the nomenclature should probably not be too strange relative to the existing naming used for CoVs.

@taltman taltman created this issue from a note in Serratus Annotation (To do) Jul 10, 2020
@rcedgar
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rcedgar commented Jul 10, 2020

Serratax provides the identity of the source organism. They allow BLAST top hits as an approximate guide down to genus, which is a bad method for our situation. Serratax is much better because it reliably resolves sub-genus and species, while even genus can be wrong with BLAST (e.g. Bobbie). Perhaps this will need a discussion with GB, and possibly they won't allow it, but Serratax gives much better predictions than blast top hit to genus -- this is exactly why I implemented Serratax!

@rcedgar
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rcedgar commented Jul 11, 2020

Can we close this? Or unassign me? From my perspective Serratax is the solution.

@rcedgar
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rcedgar commented Jul 22, 2020

@taltman Can we close this? Or unassign me? From my perspective Serratax is the solution. If there is an open issue for me, please clarify, thanks.

@ababaian
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I think source in this case is host organism not virus

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