There is a need to update the vignettes for the ToxCast pipeline as outlined in: #210.

Here are the broad components for Data processing that may be relevant to update with the tcplfit2 package updates:

Data processing vignette updates to encompass:

• New overwrite bidirectional mc and sc methods
• Processing of all well types, even where NA/0 conc given conc fix to dev
• BMD bounds
• default error function
• poly2 biphasic updates

Points identified as points that need to be updated, or consider updates:

• Ensure Level 4 incorporates both bidirectional and biphasic aspects of modeling.
• Table 7 update with poly2 biphasic
• Figure 2 Update
• Figure 3 may need updated as well
• Table 9 may need updated
• Figure 4 may need updated as well

Note, there may be other necessary updates -- or comparisons/explanations, particularly considering the poly2 biphasic updates. Please use this as a starting point and may be expanded as necessary for the relevant audience.