Mast Cell Activation Syndrome (MCAS) can lead to a wide range of symptoms that can affect various organ systems. These symptoms can vary from person to person and may be mild or severe.
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Skin Symptoms: Itching (pruritus), flushing or redness of the skin. hives (urticaria). swelling (angioedema), rashes.
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Gastrointestinal Symptoms: Abdominal pain or cramping, diarrhea, nausea and vomiting, gastroesophageal reflux (GERD), food intolerances or sensitivities.
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Respiratory Symptoms: Wheezing, shortness of breath, coughing, congestion, sinus symptoms.
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Cardiovascular Symptoms: Rapid or irregular heartbeat (tachycardia, arrhythmias), low blood pressure (hypotension), fainting or near-fainting (syncope).
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Neurological Symptoms: Headaches, migraines, brain fog, cognitive impairment, dizziness, anxiety, panic attacks, neuropathic pain.
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Musculoskeletal Symptoms: Joint pain (arthralgia), muscle pain (myalgia), bone pain, weakness.
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Urological Symptoms: Frequent urination, painful urination, interstitial cystitis-like symptoms.
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Endocrine and Autonomic Symptoms: Fatigue, insomnia, temperature dysregulation (feeling too hot or too cold), sweating, weight fluctuations.
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Allergic Reactions: Anaphylaxis (severe and potentially life-threatening allergic reaction), increased sensitivity to allergens and other triggers