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Diphenhydramine

Diphenhydramine is an antihistamine that is commonly used to relieve symptoms associated with allergies and allergic reactions. Brand name: Benadryl.

It is available over-the-counter. Be aware that some Diphenhydramine medications contain artificial colors that may affect individuals, so ask about colorless versions.

Key points:

  • Mechanism of Action: Diphenhydramine works by blocking the effects of histamine, a natural substance produced by the body during an allergic reaction.

  • Indications: It is used to relieve symptoms of allergies, including itching, rash, watery eyes, sneezing, and runny nose. It is also used to treat motion sickness, insomnia (as a sleep aid), and symptoms of the common cold.

  • Forms: It is available in various forms, including oral tablets, capsules, liquid, and as a topical cream.

  • Sedative Effect: Diphenhydramine has a sedative effect and can cause drowsiness. Because of this, it is often used as a sleep aid.

  • Timing: Effects typically last for 4-6 hours.

  • Side Effects: Common side effects may include drowsiness, dry mouth, blurred vision, constipation, or urinary retention. It may also cause excitability, especially in children.

  • Interactions: Diphenhydramine may interact with other medications, including central nervous system depressants.