Review 'central nervous system tuberculosis' and add children

[allenbaron]

'central nervous system tuberculosis' (DOID:1638) currently has xrefs to:

• ICD9CM:013.2 = Tuberculoma of brain
• MESH:D016862 = Tuberculoma, Intracranial
• UMLS_CUI:C0085388

These should probably be replaced with:

• ICD9CM:013 = Tuberculosis of meninges and central nervous system
• MESH:D020306 = Tuberculosis, Central Nervous System
• UMLS CUI:C0275904

Potential children

1. A new child of DOID:1638 may be needed that corresponds with the current xrefs on that disease named 'intracranial tuberculoma' (based on MeSH)??
2. MeSH also has 'meningeal tuberculoma' (MESH:D014390)
3. Also consider adding 'spinal tuberculosis' as a child of DOID:1638.
   • Possible synonyms (ordered by amount of use):
     • Pott's disease --> https://europepmc.org/search?query=%22pott%27s%20disease%22
     • Pott disease --> https://europepmc.org/search?query=%22pott%20disease%22
     • Pott's disease of the spine --> https://europepmc.org/search?query=%22pott%27s%20disease%20of%20the%20spine%22
   • References:
     • https://europepmc.org/search?query=%22spinal%20tuberculosis%22
     • Pott Disease StatPearls
     • Pott Disease Wikipedia
     • https://patient.info/doctor/spinal-tuberculosis

[allenbaron]

It looks like 'spinal tuberculosis' is not considered a CNS tuberculosis but instead a bone/joint tuberculosis. This arrangement is supported by:

• MESH:D014399
• IC9CM:015.0
• ICD10CM:A18.01, for hierarchy: https://www.icd10data.com/ICD10CM/Codes/A00-B99/A15-A19/A18-

That could possibly make it a child of 'skeletal tuberculosis' (DOID:1639).

Another potentially useful reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184481/

[lschriml]

When looking at ICD9, MeSH -- I look to see if the disease terms are words that were previously used in a publication, but are no longer in use, asking were the terms really representing different diseases.
For this disease, I would add the additional xrefs mentioned above to 'CNS tuberculosis'

add spinal tuberculosis as a synonym for skeletal tuberculosis