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Guidance on identifying and masking specific bins before balancing using FAN-C Python API #173

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kalavattam opened this issue Oct 11, 2023 · 0 comments

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@kalavattam
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kalavattam commented Oct 11, 2023

Thank you again for creating and maintaining this excellent program.

I am aiming to mask specific bins across multiple FAN-C .hic contact matrices. My tentative goal is to record the bin indices in a vector. Then, I want to apply the vector of indices to each of the matrices to mask these bins before performing KR balancing. Or is it perhaps better to use an approach in which we specify genomic regions to mask? In any event, maybe these can be achieved using the FAN-C Python API. Since I am new to it, I wonder if you have any guidance on the specific classes, functions, or methods to use for this purpose?

Looking forward and feedback or insights. Thank you.

@kalavattam kalavattam changed the title Guidance on identifying and masking specific bins before KR Balancing using FAN-C Python API Guidance on identifying and masking specific bins before balancing using FAN-C Python API Oct 12, 2023
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