diff --git a/src/Node/Expression/CallExpression.php b/src/Node/Expression/CallExpression.php
index 5c7326bf4..fd218b007 100644
--- a/src/Node/Expression/CallExpression.php
+++ b/src/Node/Expression/CallExpression.php
@@ -37,7 +37,7 @@ protected function compileCallable(Compiler $compiler)
                 } else {
                     $compiler->raw(sprintf('$this->env->getRuntime(\'%s\')->%s', $callable[0], $callable[1]));
                 }
-            } elseif (\is_array($callable) && $callable[0] instanceof ExtensionInterface) {
+            } elseif (\is_array($callable) && $callable[0] instanceof ExtensionInterface && false === strpos($callable[1], 'closure:')) {
                 $class = \get_class($callable[0]);
                 if (!$compiler->getEnvironment()->hasExtension($class)) {
                     // Compile a non-optimized call to trigger a \Twig\Error\RuntimeError, which cannot be a compile-time error