power calculator for Genetic Risk Scores (GRS)
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Updated
Aug 9, 2018 - R
power calculator for Genetic Risk Scores (GRS)
Toolkit for the efficient construction and analysis of polygenic risk scores in R.
As a part of COVID-19 Host Genetics Initiative, we perform the following set of analyses to better understand the genetic basis of COVID-19 susceptibility and severity.
Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular manifestations in patients undergoing carotid endarterectomy
Polygenic risk modeling with latent trait-related genetic components
This repository contains the programming codes used in Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types https://advances.sciencemag.org/content/7/3/eabd9036
Cross-Trait Penalized Regression using Summary Statistics
Those are the code files for producing the PheWAS analyses in the manuscript "Phenome-Wide Association Study of Polygenic Risk Score for Alzheimer’s Disease in Electronic Health Records". Part of our analyses included sensitive genomic data. Codes to produce AD PRS were not included here.
Polygenic Risk Scores (PRS) pipeline.
Multi Kernel Linear Mixed Models for Complex Phenotype Prediction
Toolkit to aid generation of advanced Polygenic Risk Scores (PRS) including SNP-allele tagging and interaction models, especially in HLA. Developed and maintained by Seth Sharp (S.sharp@exeter.ac.uk).
quincunx: an R package to query, download and wrangle PGS Catalog data
Software program for generating synthetic datasets for genotypes and phenotypes
A toolkit to calculate polygenic scores using PLINK2, PRS-CS, RapidoPGS, or PRSice2.
quincunx: an R package to query, download and wrangle PGS Catalog data
Machine Learning in Genomics and Healthcare (COMP 565) Project
Machine Learning in Genomics and Healthcare (COMP 565) Project
INVESTIGATING THE ASSOCIATION BETWEEN POLYGENIC RISK SCORE OF ADIPOSE TISSUE FUNCTION AND CARDIOVASCULAR DISEASE
GAUDI: a penalized regression based PRS method designed specifically for admixed individuals
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