Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Support extra sib in twin models #161

Open
2 tasks done
tbates opened this issue Jun 9, 2021 · 2 comments
Open
2 tasks done

Support extra sib in twin models #161

tbates opened this issue Jun 9, 2021 · 2 comments
Assignees

Comments

@tbates
Copy link
Owner

tbates commented Jun 9, 2021

Following changes in #160, umx's twin models can reasonably easily be extended to include nSib >2 (need to change the expCovMZ/DZ algebras, the extra means should all be done automagically.

  • umxACEv
  • umxACE
@tbates tbates self-assigned this Jun 9, 2021
@tbates tbates added this to To do in bigger families via automation Jun 9, 2021
@tbates tbates moved this from To do to In progress in bigger families Jun 9, 2021
@mcneale
Copy link
Collaborator

mcneale commented Jun 9, 2021 via email

@tbates
Copy link
Owner Author

tbates commented Jun 9, 2021

H asked me about it and it turned out to be a fun problem to code into 'umx'.

Was using data to test where a covariate "age" correlated .8 with the DV "bmi" in twins and zero in the third sib, which made it look like there was an error in the new functions (h2 estimated at 0 in the 3 sib+cov model)...

Handily, the ACEv model however also gave the largest negative Variance estimate I've ever seen, which was a nice heads-up that the data might not have been simulated correctly!

So +1 for ACEv :-)

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
bigger families
In progress
Development

No branches or pull requests

2 participants