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animal to human genotype-phenotype prediction #118

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kexinhuang12345 opened this issue Sep 24, 2021 · 0 comments
Open

animal to human genotype-phenotype prediction #118

kexinhuang12345 opened this issue Sep 24, 2021 · 0 comments
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@kexinhuang12345
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Describe the problem

The gap between animal testing and human clinical trial is unfathomable. This is one of the reason why a drug is good in preclinical studies but show no efficacy in clinical trials. ML can potentially alleviate the issue.

The task is defined as: Given genotype-phenotype data of animals and only the genotype data of humans, train the model to fit the phenotype from the genotype and transfer this model to humans.

Reference: https://www.nature.com/articles/sdata20149

Describe the solution you'd like

from tdc.single_pred import GenoPhenoTrans
data = GenoPhenoTrans(name = 'sbv-improver',  path = './data')

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@kexinhuang12345 kexinhuang12345 self-assigned this Sep 24, 2021
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