models/toy_atp/toy_atp.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# toy_atp"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "sbmlutils: 0.1.8\n",
      "cobra: 0.9.1\n",
      "roadrunner: 1.4.24\n",
      "/home/mkoenig/git/dfba/models/toy_atp\n"
     ]
    }
   ],
   "source": [
    "from __future__ import absolute_import, print_function, division\n",
    "import os\n",
    "from matplotlib import pyplot as plt\n",
    "import pandas as pd\n",
    "import numpy as np\n",
    "import cobra\n",
    "import roadrunner\n",
    "\n",
    "from IPython.display import display, HTML\n",
    "\n",
    "import sbmlutils\n",
    "from sbmlutils import dfba\n",
    "from sbmlutils.dfba.simulator import simulate_dfba\n",
    "from sbmlutils.dfba import utils\n",
    "from sbmlutils.dfba import analysis\n",
    "\n",
    "analysis.set_matplotlib_parameters()\n",
    "\n",
    "print('sbmlutils:', sbmlutils.__version__)\n",
    "print('cobra:', cobra.__version__)\n",
    "print('roadrunner:', roadrunner.__version__)\n",
    "\n",
    "print(os.getcwd())"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Simulation settings"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "model_id = \"toy_atp\"\n",
    "tend = 15\n",
    "dt = 0.1\n",
    "abs_tol=1E-15\n",
    "rel_tol=1E-15"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": [
    "def plot_results(df, mid, key='mk'):\n",
    "    fig, (ax1, ax2) = plt.subplots(nrows=1, ncols=2, figsize=(10, 5))\n",
    "    plt.subplots_adjust(wspace=0.3)\n",
    "    kwargs = {}\n",
    "    for ax in (ax1, ax2):\n",
    "        if key == 'mk':\n",
    "            ax.plot(df.time, df['[atp]'], color='darkred', label=\"[atp]\", **kwargs)\n",
    "            ax.plot(df.time, df['[adp]'], color='darkblue', label=\"[adp]\", **kwargs)\n",
    "            ax.plot(df.time, df['[glc]'], color='darkgreen', label=\"[glc]\", **kwargs)\n",
    "            ax.plot(df.time, df['[pyr]'], color='darkorange', label=\"[pyr]\", **kwargs)\n",
    "            ax.plot(df.time, df['[atp]']+df['[adp]'], color='black', label=\"[atp]+[adp]\", **kwargs)\n",
    "            \n",
    "            \n",
    "            \n",
    "            \n",
    "        elif key == 'lw':\n",
    "            ax.plot(df.time, df['[ATP]'], color='darkred', label=\"[ATP]\", **kwargs)\n",
    "            ax.plot(df.time, df['[ADP]'], color='darkblue', label=\"[ADP]\", **kwargs)\n",
    "            ax.plot(df.time, df['[Glucose]'], color='darkgreen', label=\"[Glucose]\", **kwargs)\n",
    "            ax.plot(df.time, df['[Pyruvate]'], color='darkorange', label=\"[Pyruvate]\", **kwargs)\n",
    "            ax.plot(df.time, df['[ATP]']+df['[ADP]'], color='black', label=\"[ATP]+[ADP]\", **kwargs)\n",
    "\n",
    "    ax2.set_yscale('log')\n",
    "\n",
    "    for ax in (ax1, ax2):\n",
    "        ax.set_ylabel('Concentrations')\n",
    "\n",
    "    for ax in (ax1, ax2):\n",
    "        ax.set_title(mid)\n",
    "        ax.set_xlabel('time')\n",
    "        ax.legend()\n",
    "\n",
    "    plt.show()\n",
    "    return fig "
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## mk model"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {
    "scrolled": false
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "./mk/v12/toy_atp_top.xml\n",
      "toy_atp_mk_v12-sbmlutils_dt0.1_tend15\n",
      "--------------------------------------------------------------------------------\n",
      "ODE integrator settings\n",
      "--------------------------------------------------------------------------------\n",
      "<roadrunner.RoadRunner() { \n",
      "'this' : 0x4b3c490\n",
      "'modelLoaded' : true\n",
      "'modelName' : toy_atp (TOP)\n",
      "'libSBMLVersion' : LibSBML Version: 5.14.0\n",
      "'jacobianStepSize' : 1e-05\n",
      "'conservedMoietyAnalysis' : false\n",
      "'simulateOptions' : \n",
      "< roadrunner.SimulateOptions() \n",
      "{ \n",
      "'this' : 0x4b47d00, \n",
      "'reset' : 0,\n",
      "'structuredResult' : 0,\n",
      "'copyResult' : 1,\n",
      "'steps' : 50,\n",
      "'start' : 0,\n",
      "'duration' : 5\n",
      "}>, \n",
      "'integrator' : \n",
      "< roadrunner.Integrator() >\n",
      "  name: cvode\n",
      "  settings:\n",
      "      relative_tolerance: 0.000000000000001\n",
      "      absolute_tolerance: 0.000000000000001\n",
      "                   stiff: true\n",
      "       maximum_bdf_order: 5\n",
      "     maximum_adams_order: 12\n",
      "       maximum_num_steps: 20000\n",
      "       maximum_time_step: 0\n",
      "       minimum_time_step: 0\n",
      "       initial_time_step: 0\n",
      "          multiple_steps: false\n",
      "      variable_step_size: false\n",
      "\n",
      "}>\n",
      "--------------------------------------------------------------------------------\n",
      "\n",
      "Simulation time     : 0.945 [s]\n",
      "Total time          : 1.071 [s]\n",
      "Overhead time       : 0.125 [s] (11.7 %)\n",
      "\n"
     ]
    },
    {
     "data": {
      "image/png": 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A9s2bN9OrVy984+i5XPqWOyb9Z/gyBVpeDa2ucToapZQKOeFUcwZQq2FD2gwa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      "text/plain": [
       "<matplotlib.figure.Figure at 0x7fbab9191630>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
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       "<div>\n",
       "<style scoped>\n",
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       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
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       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>time</th>\n",
       "      <th>[adp]</th>\n",
       "      <th>[atp]</th>\n",
       "      <th>[dummy_S]</th>\n",
       "      <th>[fba__adp]</th>\n",
       "      <th>[fba__atp]</th>\n",
       "      <th>[fba__fru16bp]</th>\n",
       "      <th>[fba__glc]</th>\n",
       "      <th>[fba__pg2]</th>\n",
       "      <th>[fba__pyr]</th>\n",
       "      <th>...</th>\n",
       "      <th>lb_EX_glc</th>\n",
       "      <th>lb_EX_pyr</th>\n",
       "      <th>pEX_adp</th>\n",
       "      <th>pEX_atp</th>\n",
       "      <th>pEX_glc</th>\n",
       "      <th>pEX_pyr</th>\n",
       "      <th>ub_EX_adp</th>\n",
       "      <th>ub_EX_atp</th>\n",
       "      <th>ub_EX_glc</th>\n",
       "      <th>ub_EX_pyr</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0.0</th>\n",
       "      <td>0.0</td>\n",
       "      <td>1.000000</td>\n",
       "      <td>2.000000e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-5.000000e+01</td>\n",
       "      <td>-0.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.1</th>\n",
       "      <td>0.1</td>\n",
       "      <td>0.995243</td>\n",
       "      <td>2.004757e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.950000e+01</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.2</th>\n",
       "      <td>0.2</td>\n",
       "      <td>0.990498</td>\n",
       "      <td>2.009502e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.900000e+01</td>\n",
       "      <td>-2.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.3</th>\n",
       "      <td>0.3</td>\n",
       "      <td>0.985763</td>\n",
       "      <td>2.014237e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.850000e+01</td>\n",
       "      <td>-3.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.4</th>\n",
       "      <td>0.4</td>\n",
       "      <td>0.981038</td>\n",
       "      <td>2.018962e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.800000e+01</td>\n",
       "      <td>-4.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.5</th>\n",
       "      <td>0.5</td>\n",
       "      <td>0.976324</td>\n",
       "      <td>2.023676e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.750000e+01</td>\n",
       "      <td>-5.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.6</th>\n",
       "      <td>0.6</td>\n",
       "      <td>0.971620</td>\n",
       "      <td>2.028380e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.700000e+01</td>\n",
       "      <td>-6.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.7</th>\n",
       "      <td>0.7</td>\n",
       "      <td>0.966927</td>\n",
       "      <td>2.033073e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.650000e+01</td>\n",
       "      <td>-7.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.8</th>\n",
       "      <td>0.8</td>\n",
       "      <td>0.962244</td>\n",
       "      <td>2.037756e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.600000e+01</td>\n",
       "      <td>-8.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>0.9</th>\n",
       "      <td>0.9</td>\n",
       "      <td>0.957571</td>\n",
       "      <td>2.042429e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.550000e+01</td>\n",
       "      <td>-9.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.0</th>\n",
       "      <td>1.0</td>\n",
       "      <td>0.952909</td>\n",
       "      <td>2.047091e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.500000e+01</td>\n",
       "      <td>-10.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.1</th>\n",
       "      <td>1.1</td>\n",
       "      <td>0.948257</td>\n",
       "      <td>2.051743e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.450000e+01</td>\n",
       "      <td>-11.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.2</th>\n",
       "      <td>1.2</td>\n",
       "      <td>0.943614</td>\n",
       "      <td>2.056386e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.400000e+01</td>\n",
       "      <td>-12.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.3</th>\n",
       "      <td>1.3</td>\n",
       "      <td>0.938982</td>\n",
       "      <td>2.061018e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.350000e+01</td>\n",
       "      <td>-13.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.4</th>\n",
       "      <td>1.4</td>\n",
       "      <td>0.934359</td>\n",
       "      <td>2.065641e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.300000e+01</td>\n",
       "      <td>-14.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.5</th>\n",
       "      <td>1.5</td>\n",
       "      <td>0.929747</td>\n",
       "      <td>2.070253e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.250000e+01</td>\n",
       "      <td>-15.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.6</th>\n",
       "      <td>1.6</td>\n",
       "      <td>0.925144</td>\n",
       "      <td>2.074856e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.200000e+01</td>\n",
       "      <td>-16.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.7</th>\n",
       "      <td>1.7</td>\n",
       "      <td>0.920551</td>\n",
       "      <td>2.079449e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.150000e+01</td>\n",
       "      <td>-17.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.8</th>\n",
       "      <td>1.8</td>\n",
       "      <td>0.915967</td>\n",
       "      <td>2.084033e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.100000e+01</td>\n",
       "      <td>-18.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1.9</th>\n",
       "      <td>1.9</td>\n",
       "      <td>0.911393</td>\n",
       "      <td>2.088607e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.050000e+01</td>\n",
       "      <td>-19.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.0</th>\n",
       "      <td>2.0</td>\n",
       "      <td>0.906829</td>\n",
       "      <td>2.093171e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-4.000000e+01</td>\n",
       "      <td>-20.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.1</th>\n",
       "      <td>2.1</td>\n",
       "      <td>0.902274</td>\n",
       "      <td>2.097726e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.950000e+01</td>\n",
       "      <td>-21.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.2</th>\n",
       "      <td>2.2</td>\n",
       "      <td>0.897728</td>\n",
       "      <td>2.102272e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.900000e+01</td>\n",
       "      <td>-22.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.3</th>\n",
       "      <td>2.3</td>\n",
       "      <td>0.893192</td>\n",
       "      <td>2.106808e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.850000e+01</td>\n",
       "      <td>-23.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.4</th>\n",
       "      <td>2.4</td>\n",
       "      <td>0.888666</td>\n",
       "      <td>2.111334e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.800000e+01</td>\n",
       "      <td>-24.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.5</th>\n",
       "      <td>2.5</td>\n",
       "      <td>0.884148</td>\n",
       "      <td>2.115852e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.750000e+01</td>\n",
       "      <td>-25.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.6</th>\n",
       "      <td>2.6</td>\n",
       "      <td>0.879640</td>\n",
       "      <td>2.120360e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.700000e+01</td>\n",
       "      <td>-26.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.7</th>\n",
       "      <td>2.7</td>\n",
       "      <td>0.875140</td>\n",
       "      <td>2.124860e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.650000e+01</td>\n",
       "      <td>-27.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.8</th>\n",
       "      <td>2.8</td>\n",
       "      <td>0.870650</td>\n",
       "      <td>2.129350e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.600000e+01</td>\n",
       "      <td>-28.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2.9</th>\n",
       "      <td>2.9</td>\n",
       "      <td>0.866169</td>\n",
       "      <td>2.133831e+00</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-3.550000e+01</td>\n",
       "      <td>-29.0</td>\n",
       "      <td>-1.0</td>\n",
       "      <td>1.0</td>\n",
       "      <td>-0.5</td>\n",
       "      <td>1.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.1</th>\n",
       "      <td>12.1</td>\n",
       "      <td>2.508342</td>\n",
       "      <td>4.916580e-01</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.2</th>\n",
       "      <td>12.2</td>\n",
       "      <td>2.590144</td>\n",
       "      <td>4.098558e-01</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.3</th>\n",
       "      <td>12.3</td>\n",
       "      <td>2.668828</td>\n",
       "      <td>3.311725e-01</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.4</th>\n",
       "      <td>12.4</td>\n",
       "      <td>2.743339</td>\n",
       "      <td>2.566608e-01</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.5</th>\n",
       "      <td>12.5</td>\n",
       "      <td>2.812136</td>\n",
       "      <td>1.878644e-01</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.6</th>\n",
       "      <td>12.6</td>\n",
       "      <td>2.872990</td>\n",
       "      <td>1.270099e-01</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.7</th>\n",
       "      <td>12.7</td>\n",
       "      <td>2.922976</td>\n",
       "      <td>7.702430e-02</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.8</th>\n",
       "      <td>12.8</td>\n",
       "      <td>2.959267</td>\n",
       "      <td>4.073286e-02</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12.9</th>\n",
       "      <td>12.9</td>\n",
       "      <td>2.981318</td>\n",
       "      <td>1.868174e-02</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.0</th>\n",
       "      <td>13.0</td>\n",
       "      <td>2.992328</td>\n",
       "      <td>7.672474e-03</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.1</th>\n",
       "      <td>13.1</td>\n",
       "      <td>2.997041</td>\n",
       "      <td>2.958777e-03</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.2</th>\n",
       "      <td>13.2</td>\n",
       "      <td>2.998891</td>\n",
       "      <td>1.108797e-03</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.3</th>\n",
       "      <td>13.3</td>\n",
       "      <td>2.999589</td>\n",
       "      <td>4.107610e-04</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.4</th>\n",
       "      <td>13.4</td>\n",
       "      <td>2.999848</td>\n",
       "      <td>1.515028e-04</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.5</th>\n",
       "      <td>13.5</td>\n",
       "      <td>2.999944</td>\n",
       "      <td>5.578814e-05</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.6</th>\n",
       "      <td>13.6</td>\n",
       "      <td>2.999979</td>\n",
       "      <td>2.053055e-05</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.7</th>\n",
       "      <td>13.7</td>\n",
       "      <td>2.999992</td>\n",
       "      <td>7.553746e-06</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.8</th>\n",
       "      <td>13.8</td>\n",
       "      <td>2.999997</td>\n",
       "      <td>2.779001e-06</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13.9</th>\n",
       "      <td>13.9</td>\n",
       "      <td>2.999999</td>\n",
       "      <td>1.022355e-06</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.0</th>\n",
       "      <td>14.0</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>3.761059e-07</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.1</th>\n",
       "      <td>14.1</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>1.383619e-07</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.2</th>\n",
       "      <td>14.2</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>5.090054e-08</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.3</th>\n",
       "      <td>14.3</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>1.872525e-08</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.4</th>\n",
       "      <td>14.4</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>6.888624e-09</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.5</th>\n",
       "      <td>14.5</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>2.534180e-09</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.6</th>\n",
       "      <td>14.6</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>9.322679e-10</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.7</th>\n",
       "      <td>14.7</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>3.429746e-10</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.8</th>\n",
       "      <td>14.8</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>1.261831e-10</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14.9</th>\n",
       "      <td>14.9</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>4.642107e-11</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15.0</th>\n",
       "      <td>15.0</td>\n",
       "      <td>3.000000</td>\n",
       "      <td>1.707436e-11</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>...</td>\n",
       "      <td>-2.071647e-26</td>\n",
       "      <td>-100.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "      <td>1000.0</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>151 rows × 52 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "      time     [adp]         [atp]  [dummy_S]  [fba__adp]  [fba__atp]  \\\n",
       "0.0    0.0  1.000000  2.000000e+00        0.0         0.0         0.0   \n",
       "0.1    0.1  0.995243  2.004757e+00        0.0         0.0         0.0   \n",
       "0.2    0.2  0.990498  2.009502e+00        0.0         0.0         0.0   \n",
       "0.3    0.3  0.985763  2.014237e+00        0.0         0.0         0.0   \n",
       "0.4    0.4  0.981038  2.018962e+00        0.0         0.0         0.0   \n",
       "0.5    0.5  0.976324  2.023676e+00        0.0         0.0         0.0   \n",
       "0.6    0.6  0.971620  2.028380e+00        0.0         0.0         0.0   \n",
       "0.7    0.7  0.966927  2.033073e+00        0.0         0.0         0.0   \n",
       "0.8    0.8  0.962244  2.037756e+00        0.0         0.0         0.0   \n",
       "0.9    0.9  0.957571  2.042429e+00        0.0         0.0         0.0   \n",
       "1.0    1.0  0.952909  2.047091e+00        0.0         0.0         0.0   \n",
       "1.1    1.1  0.948257  2.051743e+00        0.0         0.0         0.0   \n",
       "1.2    1.2  0.943614  2.056386e+00        0.0         0.0         0.0   \n",
       "1.3    1.3  0.938982  2.061018e+00        0.0         0.0         0.0   \n",
       "1.4    1.4  0.934359  2.065641e+00        0.0         0.0         0.0   \n",
       "1.5    1.5  0.929747  2.070253e+00        0.0         0.0         0.0   \n",
       "1.6    1.6  0.925144  2.074856e+00        0.0         0.0         0.0   \n",
       "1.7    1.7  0.920551  2.079449e+00        0.0         0.0         0.0   \n",
       "1.8    1.8  0.915967  2.084033e+00        0.0         0.0         0.0   \n",
       "1.9    1.9  0.911393  2.088607e+00        0.0         0.0         0.0   \n",
       "2.0    2.0  0.906829  2.093171e+00        0.0         0.0         0.0   \n",
       "2.1    2.1  0.902274  2.097726e+00        0.0         0.0         0.0   \n",
       "2.2    2.2  0.897728  2.102272e+00        0.0         0.0         0.0   \n",
       "2.3    2.3  0.893192  2.106808e+00        0.0         0.0         0.0   \n",
       "2.4    2.4  0.888666  2.111334e+00        0.0         0.0         0.0   \n",
       "2.5    2.5  0.884148  2.115852e+00        0.0         0.0         0.0   \n",
       "2.6    2.6  0.879640  2.120360e+00        0.0         0.0         0.0   \n",
       "2.7    2.7  0.875140  2.124860e+00        0.0         0.0         0.0   \n",
       "2.8    2.8  0.870650  2.129350e+00        0.0         0.0         0.0   \n",
       "2.9    2.9  0.866169  2.133831e+00        0.0         0.0         0.0   \n",
       "...    ...       ...           ...        ...         ...         ...   \n",
       "12.1  12.1  2.508342  4.916580e-01        0.0         0.0         0.0   \n",
       "12.2  12.2  2.590144  4.098558e-01        0.0         0.0         0.0   \n",
       "12.3  12.3  2.668828  3.311725e-01        0.0         0.0         0.0   \n",
       "12.4  12.4  2.743339  2.566608e-01        0.0         0.0         0.0   \n",
       "12.5  12.5  2.812136  1.878644e-01        0.0         0.0         0.0   \n",
       "12.6  12.6  2.872990  1.270099e-01        0.0         0.0         0.0   \n",
       "12.7  12.7  2.922976  7.702430e-02        0.0         0.0         0.0   \n",
       "12.8  12.8  2.959267  4.073286e-02        0.0         0.0         0.0   \n",
       "12.9  12.9  2.981318  1.868174e-02        0.0         0.0         0.0   \n",
       "13.0  13.0  2.992328  7.672474e-03        0.0         0.0         0.0   \n",
       "13.1  13.1  2.997041  2.958777e-03        0.0         0.0         0.0   \n",
       "13.2  13.2  2.998891  1.108797e-03        0.0         0.0         0.0   \n",
       "13.3  13.3  2.999589  4.107610e-04        0.0         0.0         0.0   \n",
       "13.4  13.4  2.999848  1.515028e-04        0.0         0.0         0.0   \n",
       "13.5  13.5  2.999944  5.578814e-05        0.0         0.0         0.0   \n",
       "13.6  13.6  2.999979  2.053055e-05        0.0         0.0         0.0   \n",
       "13.7  13.7  2.999992  7.553746e-06        0.0         0.0         0.0   \n",
       "13.8  13.8  2.999997  2.779001e-06        0.0         0.0         0.0   \n",
       "13.9  13.9  2.999999  1.022355e-06        0.0         0.0         0.0   \n",
       "14.0  14.0  3.000000  3.761059e-07        0.0         0.0         0.0   \n",
       "14.1  14.1  3.000000  1.383619e-07        0.0         0.0         0.0   \n",
       "14.2  14.2  3.000000  5.090054e-08        0.0         0.0         0.0   \n",
       "14.3  14.3  3.000000  1.872525e-08        0.0         0.0         0.0   \n",
       "14.4  14.4  3.000000  6.888624e-09        0.0         0.0         0.0   \n",
       "14.5  14.5  3.000000  2.534180e-09        0.0         0.0         0.0   \n",
       "14.6  14.6  3.000000  9.322679e-10        0.0         0.0         0.0   \n",
       "14.7  14.7  3.000000  3.429746e-10        0.0         0.0         0.0   \n",
       "14.8  14.8  3.000000  1.261831e-10        0.0         0.0         0.0   \n",
       "14.9  14.9  3.000000  4.642107e-11        0.0         0.0         0.0   \n",
       "15.0  15.0  3.000000  1.707436e-11        0.0         0.0         0.0   \n",
       "\n",
       "      [fba__fru16bp]  [fba__glc]  [fba__pg2]  [fba__pyr]    ...      \\\n",
       "0.0              0.0         0.0         0.0         0.0    ...       \n",
       "0.1              0.0         0.0         0.0         0.0    ...       \n",
       "0.2              0.0         0.0         0.0         0.0    ...       \n",
       "0.3              0.0         0.0         0.0         0.0    ...       \n",
       "0.4              0.0         0.0         0.0         0.0    ...       \n",
       "0.5              0.0         0.0         0.0         0.0    ...       \n",
       "0.6              0.0         0.0         0.0         0.0    ...       \n",
       "0.7              0.0         0.0         0.0         0.0    ...       \n",
       "0.8              0.0         0.0         0.0         0.0    ...       \n",
       "0.9              0.0         0.0         0.0         0.0    ...       \n",
       "1.0              0.0         0.0         0.0         0.0    ...       \n",
       "1.1              0.0         0.0         0.0         0.0    ...       \n",
       "1.2              0.0         0.0         0.0         0.0    ...       \n",
       "1.3              0.0         0.0         0.0         0.0    ...       \n",
       "1.4              0.0         0.0         0.0         0.0    ...       \n",
       "1.5              0.0         0.0         0.0         0.0    ...       \n",
       "1.6              0.0         0.0         0.0         0.0    ...       \n",
       "1.7              0.0         0.0         0.0         0.0    ...       \n",
       "1.8              0.0         0.0         0.0         0.0    ...       \n",
       "1.9              0.0         0.0         0.0         0.0    ...       \n",
       "2.0              0.0         0.0         0.0         0.0    ...       \n",
       "2.1              0.0         0.0         0.0         0.0    ...       \n",
       "2.2              0.0         0.0         0.0         0.0    ...       \n",
       "2.3              0.0         0.0         0.0         0.0    ...       \n",
       "2.4              0.0         0.0         0.0         0.0    ...       \n",
       "2.5              0.0         0.0         0.0         0.0    ...       \n",
       "2.6              0.0         0.0         0.0         0.0    ...       \n",
       "2.7              0.0         0.0         0.0         0.0    ...       \n",
       "2.8              0.0         0.0         0.0         0.0    ...       \n",
       "2.9              0.0         0.0         0.0         0.0    ...       \n",
       "...              ...         ...         ...         ...    ...       \n",
       "12.1             0.0         0.0         0.0         0.0    ...       \n",
       "12.2             0.0         0.0         0.0         0.0    ...       \n",
       "12.3             0.0         0.0         0.0         0.0    ...       \n",
       "12.4             0.0         0.0         0.0         0.0    ...       \n",
       "12.5             0.0         0.0         0.0         0.0    ...       \n",
       "12.6             0.0         0.0         0.0         0.0    ...       \n",
       "12.7             0.0         0.0         0.0         0.0    ...       \n",
       "12.8             0.0         0.0         0.0         0.0    ...       \n",
       "12.9             0.0         0.0         0.0         0.0    ...       \n",
       "13.0             0.0         0.0         0.0         0.0    ...       \n",
       "13.1             0.0         0.0         0.0         0.0    ...       \n",
       "13.2             0.0         0.0         0.0         0.0    ...       \n",
       "13.3             0.0         0.0         0.0         0.0    ...       \n",
       "13.4             0.0         0.0         0.0         0.0    ...       \n",
       "13.5             0.0         0.0         0.0         0.0    ...       \n",
       "13.6             0.0         0.0         0.0         0.0    ...       \n",
       "13.7             0.0         0.0         0.0         0.0    ...       \n",
       "13.8             0.0         0.0         0.0         0.0    ...       \n",
       "13.9             0.0         0.0         0.0         0.0    ...       \n",
       "14.0             0.0         0.0         0.0         0.0    ...       \n",
       "14.1             0.0         0.0         0.0         0.0    ...       \n",
       "14.2             0.0         0.0         0.0         0.0    ...       \n",
       "14.3             0.0         0.0         0.0         0.0    ...       \n",
       "14.4             0.0         0.0         0.0         0.0    ...       \n",
       "14.5             0.0         0.0         0.0         0.0    ...       \n",
       "14.6             0.0         0.0         0.0         0.0    ...       \n",
       "14.7             0.0         0.0         0.0         0.0    ...       \n",
       "14.8             0.0         0.0         0.0         0.0    ...       \n",
       "14.9             0.0         0.0         0.0         0.0    ...       \n",
       "15.0             0.0         0.0         0.0         0.0    ...       \n",
       "\n",
       "         lb_EX_glc  lb_EX_pyr  pEX_adp  pEX_atp  pEX_glc  pEX_pyr  ub_EX_adp  \\\n",
       "0.0  -5.000000e+01       -0.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.1  -4.950000e+01       -1.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.2  -4.900000e+01       -2.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.3  -4.850000e+01       -3.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.4  -4.800000e+01       -4.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.5  -4.750000e+01       -5.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.6  -4.700000e+01       -6.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.7  -4.650000e+01       -7.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.8  -4.600000e+01       -8.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "0.9  -4.550000e+01       -9.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.0  -4.500000e+01      -10.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.1  -4.450000e+01      -11.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.2  -4.400000e+01      -12.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.3  -4.350000e+01      -13.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.4  -4.300000e+01      -14.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.5  -4.250000e+01      -15.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.6  -4.200000e+01      -16.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.7  -4.150000e+01      -17.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.8  -4.100000e+01      -18.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "1.9  -4.050000e+01      -19.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.0  -4.000000e+01      -20.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.1  -3.950000e+01      -21.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.2  -3.900000e+01      -22.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.3  -3.850000e+01      -23.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.4  -3.800000e+01      -24.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.5  -3.750000e+01      -25.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.6  -3.700000e+01      -26.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.7  -3.650000e+01      -27.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.8  -3.600000e+01      -28.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "2.9  -3.550000e+01      -29.0     -1.0      1.0     -0.5      1.0     1000.0   \n",
       "...            ...        ...      ...      ...      ...      ...        ...   \n",
       "12.1 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.2 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.3 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.4 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.5 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.6 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.7 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.8 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "12.9 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.0 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.1 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.2 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.3 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.4 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.5 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.6 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.7 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.8 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "13.9 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.0 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.1 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.2 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.3 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.4 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.5 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.6 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.7 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.8 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "14.9 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "15.0 -2.071647e-26     -100.0      0.0      0.0      0.0      0.0     1000.0   \n",
       "\n",
       "      ub_EX_atp  ub_EX_glc  ub_EX_pyr  \n",
       "0.0      1000.0     1000.0     1000.0  \n",
       "0.1      1000.0     1000.0     1000.0  \n",
       "0.2      1000.0     1000.0     1000.0  \n",
       "0.3      1000.0     1000.0     1000.0  \n",
       "0.4      1000.0     1000.0     1000.0  \n",
       "0.5      1000.0     1000.0     1000.0  \n",
       "0.6      1000.0     1000.0     1000.0  \n",
       "0.7      1000.0     1000.0     1000.0  \n",
       "0.8      1000.0     1000.0     1000.0  \n",
       "0.9      1000.0     1000.0     1000.0  \n",
       "1.0      1000.0     1000.0     1000.0  \n",
       "1.1      1000.0     1000.0     1000.0  \n",
       "1.2      1000.0     1000.0     1000.0  \n",
       "1.3      1000.0     1000.0     1000.0  \n",
       "1.4      1000.0     1000.0     1000.0  \n",
       "1.5      1000.0     1000.0     1000.0  \n",
       "1.6      1000.0     1000.0     1000.0  \n",
       "1.7      1000.0     1000.0     1000.0  \n",
       "1.8      1000.0     1000.0     1000.0  \n",
       "1.9      1000.0     1000.0     1000.0  \n",
       "2.0      1000.0     1000.0     1000.0  \n",
       "2.1      1000.0     1000.0     1000.0  \n",
       "2.2      1000.0     1000.0     1000.0  \n",
       "2.3      1000.0     1000.0     1000.0  \n",
       "2.4      1000.0     1000.0     1000.0  \n",
       "2.5      1000.0     1000.0     1000.0  \n",
       "2.6      1000.0     1000.0     1000.0  \n",
       "2.7      1000.0     1000.0     1000.0  \n",
       "2.8      1000.0     1000.0     1000.0  \n",
       "2.9      1000.0     1000.0     1000.0  \n",
       "...         ...        ...        ...  \n",
       "12.1     1000.0     1000.0     1000.0  \n",
       "12.2     1000.0     1000.0     1000.0  \n",
       "12.3     1000.0     1000.0     1000.0  \n",
       "12.4     1000.0     1000.0     1000.0  \n",
       "12.5     1000.0     1000.0     1000.0  \n",
       "12.6     1000.0     1000.0     1000.0  \n",
       "12.7     1000.0     1000.0     1000.0  \n",
       "12.8     1000.0     1000.0     1000.0  \n",
       "12.9     1000.0     1000.0     1000.0  \n",
       "13.0     1000.0     1000.0     1000.0  \n",
       "13.1     1000.0     1000.0     1000.0  \n",
       "13.2     1000.0     1000.0     1000.0  \n",
       "13.3     1000.0     1000.0     1000.0  \n",
       "13.4     1000.0     1000.0     1000.0  \n",
       "13.5     1000.0     1000.0     1000.0  \n",
       "13.6     1000.0     1000.0     1000.0  \n",
       "13.7     1000.0     1000.0     1000.0  \n",
       "13.8     1000.0     1000.0     1000.0  \n",
       "13.9     1000.0     1000.0     1000.0  \n",
       "14.0     1000.0     1000.0     1000.0  \n",
       "14.1     1000.0     1000.0     1000.0  \n",
       "14.2     1000.0     1000.0     1000.0  \n",
       "14.3     1000.0     1000.0     1000.0  \n",
       "14.4     1000.0     1000.0     1000.0  \n",
       "14.5     1000.0     1000.0     1000.0  \n",
       "14.6     1000.0     1000.0     1000.0  \n",
       "14.7     1000.0     1000.0     1000.0  \n",
       "14.8     1000.0     1000.0     1000.0  \n",
       "14.9     1000.0     1000.0     1000.0  \n",
       "15.0     1000.0     1000.0     1000.0  \n",
       "\n",
       "[151 rows x 52 columns]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "version_mk = 'v12'\n",
    "sbml_mk = './mk/{}/{}_top.xml'.format(version_mk, model_id)\n",
    "mid_mk = '{}_mk_{}-sbmlutils_dt{}_tend{}'.format(model_id, version_mk, dt, tend)\n",
    "print(sbml_mk)\n",
    "print(mid_mk)\n",
    "\n",
    "# simulating\n",
    "df_mk, dfba_model_mk, dfba_simulator_mk = simulate_dfba(sbml_mk, tend=tend, dt=dt, \n",
    "                                                        rel_tol=rel_tol, abs_tol=abs_tol, show_settings=True)\n",
    "\n",
    "# figure\n",
    "fig = plot_results(df_mk, mid_mk, key=\"mk\")\n",
    "fig.savefig('./{}.png'.format(mid_mk), bbox_inches='tight')\n",
    "fig.savefig('./{}.pdf'.format(mid_mk), bbox_inches='tight')\n",
    "\n",
    "# results\n",
    "df_mk.to_csv('./{}.csv'.format(mid_mk), sep='\\t')\n",
    "display(df_mk)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {
    "collapsed": true
   },
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "dfba",
   "language": "python",
   "name": "dfba"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.5.2"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 2
}