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1be9.pdb
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1be9.pdb
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HEADER PEPTIDE RECOGNITION 20-MAY-98 1BE9
TITLE THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH
TITLE 2 A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: PSD-95;
COMPND 3 CHAIN: A;
COMPND 4 FRAGMENT: THE THIRD PDZ DOMAIN OF PSD-95;
COMPND 5 ENGINEERED: YES;
COMPND 6 MOL_ID: 2;
COMPND 7 MOLECULE: CRIPT;
COMPND 8 CHAIN: B;
COMPND 9 FRAGMENT: C-TERMINAL PEPTIDE
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS;
SOURCE 3 ORGANISM_COMMON: NORWAY RAT;
SOURCE 4 ORGANISM_TAXID: 10116;
SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;
SOURCE 6 EXPRESSION_SYSTEM_TAXID: 511693;
SOURCE 7 EXPRESSION_SYSTEM_STRAIN: BL21;
SOURCE 8 EXPRESSION_SYSTEM_PLASMID: PGEX-4T-1;
SOURCE 9 MOL_ID: 2
KEYWDS PEPTIDE RECOGNITION, PROTEIN LOCALIZATION
EXPDTA X-RAY DIFFRACTION
AUTHOR D.A.DOYLE,A.LEE,J.LEWIS,E.KIM,M.SHENG,R.MACKINNON
REVDAT 5 07-MAR-18 1BE9 1 REMARK
REVDAT 4 22-SEP-10 1BE9 1 REMARK
REVDAT 3 24-FEB-09 1BE9 1 VERSN
REVDAT 2 01-APR-03 1BE9 1 JRNL
REVDAT 1 21-OCT-98 1BE9 0
JRNL AUTH D.A.DOYLE,A.LEE,J.LEWIS,E.KIM,M.SHENG,R.MACKINNON
JRNL TITL CRYSTAL STRUCTURES OF A COMPLEXED AND PEPTIDE-FREE MEMBRANE
JRNL TITL 2 PROTEIN-BINDING DOMAIN: MOLECULAR BASIS OF PEPTIDE
JRNL TITL 3 RECOGNITION BY PDZ.
JRNL REF CELL(CAMBRIDGE,MASS.) V. 85 1067 1996
JRNL PUBL CELL PRESS
JRNL REFN ISSN 0092-8674
JRNL PMID 8674113
JRNL DOI 10.1016/S0092-8674(00)81307-0
REMARK 1
REMARK 1 REFERENCE 1
REMARK 1 AUTH D.L.DANIELS,A.R.COHEN,J.M.ANDERSON,A.T.BRUNGER
REMARK 1 TITL CRYSTAL STRUCTURE OF THE HCASK PDZ DOMAIN REVEALS THE
REMARK 1 TITL 2 STRUCTURAL BASIS OF CLASS II PDZ DOMAIN TARGET RECOGNITION
REMARK 1 REF NAT.STRUCT.BIOL. V. 5 317 1998
REMARK 1 REFN ISSN 1072-8368
REMARK 1 REFERENCE 2
REMARK 1 AUTH M.NIETHAMMER,J.G.VALTSCHANOFF,T.M.KAPOOR,D.W.ALLISON,
REMARK 1 AUTH 2 T.M.WEINBERG,A.M.CRAIG,M.SHENG
REMARK 1 TITL CRIPT, A NOVEL POSTSYNAPTIC PROTEIN THAT BINDS TO THE THIRD
REMARK 1 TITL 2 PDZ DOMAIN OF PSD-95/SAP90
REMARK 1 REF NEURON V. 20 693 1998
REMARK 1 REFN ISSN 0896-6273
REMARK 1 REFERENCE 3
REMARK 1 AUTH M.CABRAL,C.PETOSA,M.J.SUTCLIFFE,S.RAZA,O.BYRON,F.POY,
REMARK 1 AUTH 2 S.M.MARFATIA,A.H.CHISHTI,R.C.LIDDINGTON
REMARK 1 TITL CRYSTAL STRUCTURE OF A PDZ DOMAIN
REMARK 1 REF NATURE V. 382 649 1996
REMARK 1 REFN ISSN 0028-0836
REMARK 2
REMARK 2 RESOLUTION. 1.82 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 PROGRAM : X-PLOR 3.851
REMARK 3 AUTHORS : BRUNGER
REMARK 3
REMARK 3 DATA USED IN REFINEMENT.
REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.82
REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 20.00
REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL
REMARK 3 DATA CUTOFF HIGH (ABS(F)) : NULL
REMARK 3 DATA CUTOFF LOW (ABS(F)) : NULL
REMARK 3 COMPLETENESS (WORKING+TEST) (%) : NULL
REMARK 3 NUMBER OF REFLECTIONS : NULL
REMARK 3
REMARK 3 FIT TO DATA USED IN REFINEMENT.
REMARK 3 CROSS-VALIDATION METHOD : NULL
REMARK 3 FREE R VALUE TEST SET SELECTION : NULL
REMARK 3 R VALUE (WORKING SET) : 0.207
REMARK 3 FREE R VALUE : 0.278
REMARK 3 FREE R VALUE TEST SET SIZE (%) : NULL
REMARK 3 FREE R VALUE TEST SET COUNT : NULL
REMARK 3 ESTIMATED ERROR OF FREE R VALUE : NULL
REMARK 3
REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN.
REMARK 3 TOTAL NUMBER OF BINS USED : NULL
REMARK 3 BIN RESOLUTION RANGE HIGH (A) : NULL
REMARK 3 BIN RESOLUTION RANGE LOW (A) : NULL
REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : NULL
REMARK 3 REFLECTIONS IN BIN (WORKING SET) : NULL
REMARK 3 BIN R VALUE (WORKING SET) : NULL
REMARK 3 BIN FREE R VALUE : NULL
REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : NULL
REMARK 3 BIN FREE R VALUE TEST SET COUNT : NULL
REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : NULL
REMARK 3
REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.
REMARK 3 PROTEIN ATOMS : 899
REMARK 3 NUCLEIC ACID ATOMS : 0
REMARK 3 HETEROGEN ATOMS : 0
REMARK 3 SOLVENT ATOMS : 146
REMARK 3
REMARK 3 B VALUES.
REMARK 3 FROM WILSON PLOT (A**2) : NULL
REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE.
REMARK 3 B11 (A**2) : NULL
REMARK 3 B22 (A**2) : NULL
REMARK 3 B33 (A**2) : NULL
REMARK 3 B12 (A**2) : NULL
REMARK 3 B13 (A**2) : NULL
REMARK 3 B23 (A**2) : NULL
REMARK 3
REMARK 3 ESTIMATED COORDINATE ERROR.
REMARK 3 ESD FROM LUZZATI PLOT (A) : NULL
REMARK 3 ESD FROM SIGMAA (A) : NULL
REMARK 3 LOW RESOLUTION CUTOFF (A) : NULL
REMARK 3
REMARK 3 CROSS-VALIDATED ESTIMATED COORDINATE ERROR.
REMARK 3 ESD FROM C-V LUZZATI PLOT (A) : NULL
REMARK 3 ESD FROM C-V SIGMAA (A) : NULL
REMARK 3
REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES.
REMARK 3 BOND LENGTHS (A) : NULL
REMARK 3 BOND ANGLES (DEGREES) : NULL
REMARK 3 DIHEDRAL ANGLES (DEGREES) : NULL
REMARK 3 IMPROPER ANGLES (DEGREES) : NULL
REMARK 3
REMARK 3 ISOTROPIC THERMAL MODEL : NULL
REMARK 3
REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA
REMARK 3 MAIN-CHAIN BOND (A**2) : NULL ; NULL
REMARK 3 MAIN-CHAIN ANGLE (A**2) : NULL ; NULL
REMARK 3 SIDE-CHAIN BOND (A**2) : NULL ; NULL
REMARK 3 SIDE-CHAIN ANGLE (A**2) : NULL ; NULL
REMARK 3
REMARK 3 NCS MODEL : NULL
REMARK 3
REMARK 3 NCS RESTRAINTS. RMS SIGMA/WEIGHT
REMARK 3 GROUP 1 POSITIONAL (A) : NULL ; NULL
REMARK 3 GROUP 1 B-FACTOR (A**2) : NULL ; NULL
REMARK 3
REMARK 3 PARAMETER FILE 1 : NULL
REMARK 3 TOPOLOGY FILE 1 : NULL
REMARK 3
REMARK 3 OTHER REFINEMENT REMARKS: NULL
REMARK 4
REMARK 4 1BE9 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY BNL.
REMARK 100 THE DEPOSITION ID IS D_1000171651.
REMARK 200
REMARK 200 EXPERIMENTAL DETAILS
REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION
REMARK 200 DATE OF DATA COLLECTION : JAN-96
REMARK 200 TEMPERATURE (KELVIN) : 100
REMARK 200 PH : 7.5
REMARK 200 NUMBER OF CRYSTALS USED : 1
REMARK 200
REMARK 200 SYNCHROTRON (Y/N) : N
REMARK 200 RADIATION SOURCE : ROTATING ANODE
REMARK 200 BEAMLINE : NULL
REMARK 200 X-RAY GENERATOR MODEL : SIEMENS
REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M
REMARK 200 WAVELENGTH OR RANGE (A) : 1.5418
REMARK 200 MONOCHROMATOR : NI FILTER
REMARK 200 OPTICS : COLLIMATOR
REMARK 200
REMARK 200 DETECTOR TYPE : IMAGE PLATE
REMARK 200 DETECTOR MANUFACTURER : MARRESEARCH
REMARK 200 INTENSITY-INTEGRATION SOFTWARE : MOSFLM
REMARK 200 DATA SCALING SOFTWARE : SCALEPACK
REMARK 200
REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 11108
REMARK 200 RESOLUTION RANGE HIGH (A) : 1.820
REMARK 200 RESOLUTION RANGE LOW (A) : 20.000
REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 2.000
REMARK 200
REMARK 200 OVERALL.
REMARK 200 COMPLETENESS FOR RANGE (%) : 95.7
REMARK 200 DATA REDUNDANCY : NULL
REMARK 200 R MERGE (I) : 0.04800
REMARK 200 R SYM (I) : NULL
REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : NULL
REMARK 200
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.
REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.82
REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.88
REMARK 200 COMPLETENESS FOR SHELL (%) : 92.6
REMARK 200 DATA REDUNDANCY IN SHELL : NULL
REMARK 200 R MERGE FOR SHELL (I) : 0.14400
REMARK 200 R SYM FOR SHELL (I) : NULL
REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL
REMARK 200
REMARK 200 DIFFRACTION PROTOCOL: NULL
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: DIFFERENCE FOURIER
REMARK 200 ANALYSIS
REMARK 200 SOFTWARE USED: X-PLOR 3.851
REMARK 200 STARTING MODEL: NULL
REMARK 200
REMARK 200 REMARK: THE PEPTIDE-FREE PDZ3 MODEL WAS USED IN A RIGID BODY
REMARK 200 REFINEMENT, FOLLOWED BY CYCLES OF LEAST-SQUARES REFINEMENT AND
REMARK 200 MODEL BUILDING.
REMARK 280
REMARK 280 CRYSTAL
REMARK 280 SOLVENT CONTENT, VS (%): 44.87
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.23
REMARK 280
REMARK 280 CRYSTALLIZATION CONDITIONS: 0.8 M SODIUM CITRATE, 0.1 M HEPES, PH
REMARK 280 7.5
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 41 3 2
REMARK 290
REMARK 290 SYMOP SYMMETRY
REMARK 290 NNNMMM OPERATOR
REMARK 290 1555 X,Y,Z
REMARK 290 2555 -X+1/2,-Y,Z+1/2
REMARK 290 3555 -X,Y+1/2,-Z+1/2
REMARK 290 4555 X+1/2,-Y+1/2,-Z
REMARK 290 5555 Z,X,Y
REMARK 290 6555 Z+1/2,-X+1/2,-Y
REMARK 290 7555 -Z+1/2,-X,Y+1/2
REMARK 290 8555 -Z,X+1/2,-Y+1/2
REMARK 290 9555 Y,Z,X
REMARK 290 10555 -Y,Z+1/2,-X+1/2
REMARK 290 11555 Y+1/2,-Z+1/2,-X
REMARK 290 12555 -Y+1/2,-Z,X+1/2
REMARK 290 13555 Y+3/4,X+1/4,-Z+1/4
REMARK 290 14555 -Y+3/4,-X+3/4,-Z+3/4
REMARK 290 15555 Y+1/4,-X+1/4,Z+3/4
REMARK 290 16555 -Y+1/4,X+3/4,Z+1/4
REMARK 290 17555 X+3/4,Z+1/4,-Y+1/4
REMARK 290 18555 -X+1/4,Z+3/4,Y+1/4
REMARK 290 19555 -X+3/4,-Z+3/4,-Y+3/4
REMARK 290 20555 X+1/4,-Z+1/4,Y+3/4
REMARK 290 21555 Z+3/4,Y+1/4,-X+1/4
REMARK 290 22555 Z+1/4,-Y+1/4,X+3/4
REMARK 290 23555 -Z+1/4,Y+3/4,X+1/4
REMARK 290 24555 -Z+3/4,-Y+3/4,-X+3/4
REMARK 290
REMARK 290 WHERE NNN -> OPERATOR NUMBER
REMARK 290 MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000
REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000
REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 44.67000
REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000
REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 44.67000
REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 44.67000
REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 44.67000
REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 44.67000
REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 44.67000
REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000
REMARK 290 SMTRY1 5 0.000000 0.000000 1.000000 0.00000
REMARK 290 SMTRY2 5 1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY3 5 0.000000 1.000000 0.000000 0.00000
REMARK 290 SMTRY1 6 0.000000 0.000000 1.000000 44.67000
REMARK 290 SMTRY2 6 -1.000000 0.000000 0.000000 44.67000
REMARK 290 SMTRY3 6 0.000000 -1.000000 0.000000 0.00000
REMARK 290 SMTRY1 7 0.000000 0.000000 -1.000000 44.67000
REMARK 290 SMTRY2 7 -1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY3 7 0.000000 1.000000 0.000000 44.67000
REMARK 290 SMTRY1 8 0.000000 0.000000 -1.000000 0.00000
REMARK 290 SMTRY2 8 1.000000 0.000000 0.000000 44.67000
REMARK 290 SMTRY3 8 0.000000 -1.000000 0.000000 44.67000
REMARK 290 SMTRY1 9 0.000000 1.000000 0.000000 0.00000
REMARK 290 SMTRY2 9 0.000000 0.000000 1.000000 0.00000
REMARK 290 SMTRY3 9 1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY1 10 0.000000 -1.000000 0.000000 0.00000
REMARK 290 SMTRY2 10 0.000000 0.000000 1.000000 44.67000
REMARK 290 SMTRY3 10 -1.000000 0.000000 0.000000 44.67000
REMARK 290 SMTRY1 11 0.000000 1.000000 0.000000 44.67000
REMARK 290 SMTRY2 11 0.000000 0.000000 -1.000000 44.67000
REMARK 290 SMTRY3 11 -1.000000 0.000000 0.000000 0.00000
REMARK 290 SMTRY1 12 0.000000 -1.000000 0.000000 44.67000
REMARK 290 SMTRY2 12 0.000000 0.000000 -1.000000 0.00000
REMARK 290 SMTRY3 12 1.000000 0.000000 0.000000 44.67000
REMARK 290 SMTRY1 13 0.000000 1.000000 0.000000 67.00500
REMARK 290 SMTRY2 13 1.000000 0.000000 0.000000 22.33500
REMARK 290 SMTRY3 13 0.000000 0.000000 -1.000000 22.33500
REMARK 290 SMTRY1 14 0.000000 -1.000000 0.000000 67.00500
REMARK 290 SMTRY2 14 -1.000000 0.000000 0.000000 67.00500
REMARK 290 SMTRY3 14 0.000000 0.000000 -1.000000 67.00500
REMARK 290 SMTRY1 15 0.000000 1.000000 0.000000 22.33500
REMARK 290 SMTRY2 15 -1.000000 0.000000 0.000000 22.33500
REMARK 290 SMTRY3 15 0.000000 0.000000 1.000000 67.00500
REMARK 290 SMTRY1 16 0.000000 -1.000000 0.000000 22.33500
REMARK 290 SMTRY2 16 1.000000 0.000000 0.000000 67.00500
REMARK 290 SMTRY3 16 0.000000 0.000000 1.000000 22.33500
REMARK 290 SMTRY1 17 1.000000 0.000000 0.000000 67.00500
REMARK 290 SMTRY2 17 0.000000 0.000000 1.000000 22.33500
REMARK 290 SMTRY3 17 0.000000 -1.000000 0.000000 22.33500
REMARK 290 SMTRY1 18 -1.000000 0.000000 0.000000 22.33500
REMARK 290 SMTRY2 18 0.000000 0.000000 1.000000 67.00500
REMARK 290 SMTRY3 18 0.000000 1.000000 0.000000 22.33500
REMARK 290 SMTRY1 19 -1.000000 0.000000 0.000000 67.00500
REMARK 290 SMTRY2 19 0.000000 0.000000 -1.000000 67.00500
REMARK 290 SMTRY3 19 0.000000 -1.000000 0.000000 67.00500
REMARK 290 SMTRY1 20 1.000000 0.000000 0.000000 22.33500
REMARK 290 SMTRY2 20 0.000000 0.000000 -1.000000 22.33500
REMARK 290 SMTRY3 20 0.000000 1.000000 0.000000 67.00500
REMARK 290 SMTRY1 21 0.000000 0.000000 1.000000 67.00500
REMARK 290 SMTRY2 21 0.000000 1.000000 0.000000 22.33500
REMARK 290 SMTRY3 21 -1.000000 0.000000 0.000000 22.33500
REMARK 290 SMTRY1 22 0.000000 0.000000 1.000000 22.33500
REMARK 290 SMTRY2 22 0.000000 -1.000000 0.000000 22.33500
REMARK 290 SMTRY3 22 1.000000 0.000000 0.000000 67.00500
REMARK 290 SMTRY1 23 0.000000 0.000000 -1.000000 22.33500
REMARK 290 SMTRY2 23 0.000000 1.000000 0.000000 67.00500
REMARK 290 SMTRY3 23 1.000000 0.000000 0.000000 22.33500
REMARK 290 SMTRY1 24 0.000000 0.000000 -1.000000 67.00500
REMARK 290 SMTRY2 24 0.000000 -1.000000 0.000000 67.00500
REMARK 290 SMTRY3 24 -1.000000 0.000000 0.000000 67.00500
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC
REMARK 350 SOFTWARE USED: PISA
REMARK 350 TOTAL BURIED SURFACE AREA: 760 ANGSTROM**2
REMARK 350 SURFACE AREA OF THE COMPLEX: 6510 ANGSTROM**2
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -3.0 KCAL/MOL
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 GLY A 297
REMARK 465 SER A 298
REMARK 465 PRO A 299
REMARK 465 GLU A 300
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 PHE A 301 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASP A 332 CG OD1 OD2
REMARK 470 LYS B 5 CG CD CE NZ
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 GLU A 334 -59.02 7.04
REMARK 500
REMARK 500 REMARK: NULL
REMARK 800
REMARK 800 SITE
REMARK 800 SITE_IDENTIFIER: PEP
REMARK 800 EVIDENCE_CODE: UNKNOWN
REMARK 800 SITE_DESCRIPTION: RESIDUES INVOLVED IN THE BINDING OF THE FOUR C
REMARK 800 -TERMINAL RESIDUES OF CRIPT.
DBREF 1BE9 A 298 414 UNP P31016 DLG4_RAT 295 420
DBREF 1BE9 B 5 9 PDB 1BE9 1BE9 5 9
SEQADV 1BE9 A UNP P31016 VAL 297 DELETION
SEQADV 1BE9 A UNP P31016 ALA 298 DELETION
SEQADV 1BE9 A UNP P31016 LYS 299 DELETION
SEQADV 1BE9 GLU A 300 UNP P31016 ASP 300 CONFLICT
SEQADV 1BE9 PHE A 301 UNP P31016 LEU 301 CONFLICT
SEQADV 1BE9 ILE A 328 UNP P31016 VAL 328 CONFLICT
SEQADV 1BE9 A UNP P31016 LYS 403 DELETION
SEQADV 1BE9 A UNP P31016 ILE 404 DELETION
SEQADV 1BE9 A UNP P31016 HIS 405 DELETION
SEQADV 1BE9 A UNP P31016 ASP 406 DELETION
SEQADV 1BE9 A UNP P31016 LEU 407 DELETION
SEQADV 1BE9 A UNP P31016 ARG 408 DELETION
SEQADV 1BE9 ASN A 403 UNP P31016 GLU 409 CONFLICT
SEQADV 1BE9 SER A 404 UNP P31016 GLN 410 CONFLICT
SEQADV 1BE9 ARG A 405 UNP P31016 LEU 411 CONFLICT
SEQADV 1BE9 VAL A 406 UNP P31016 MET 412 CONFLICT
SEQADV 1BE9 GLY A 410 UNP P31016 LEU 416 CONFLICT
SEQADV 1BE9 ARG A 411 UNP P31016 GLY 417 CONFLICT
SEQADV 1BE9 ILE A 412 UNP P31016 SER 418 CONFLICT
SEQADV 1BE9 VAL A 413 UNP P31016 GLY 419 CONFLICT
SEQRES 1 A 119 GLY SER PRO GLU PHE LEU GLY GLU GLU ASP ILE PRO ARG
SEQRES 2 A 119 GLU PRO ARG ARG ILE VAL ILE HIS ARG GLY SER THR GLY
SEQRES 3 A 119 LEU GLY PHE ASN ILE ILE GLY GLY GLU ASP GLY GLU GLY
SEQRES 4 A 119 ILE PHE ILE SER PHE ILE LEU ALA GLY GLY PRO ALA ASP
SEQRES 5 A 119 LEU SER GLY GLU LEU ARG LYS GLY ASP GLN ILE LEU SER
SEQRES 6 A 119 VAL ASN GLY VAL ASP LEU ARG ASN ALA SER HIS GLU GLN
SEQRES 7 A 119 ALA ALA ILE ALA LEU LYS ASN ALA GLY GLN THR VAL THR
SEQRES 8 A 119 ILE ILE ALA GLN TYR LYS PRO GLU GLU TYR SER ARG PHE
SEQRES 9 A 119 GLU ALA ASN SER ARG VAL ASN SER SER GLY ARG ILE VAL
SEQRES 10 A 119 THR ASN
SEQRES 1 B 5 LYS GLN THR SER VAL
FORMUL 3 HOH *146(H2 O)
HELIX 1 1 LEU A 302 GLU A 304 5 3
HELIX 2 2 PRO A 346 SER A 350 1 5
HELIX 3 3 HIS A 372 LYS A 380 1 9
HELIX 4 4 PRO A 394 ARG A 399 1 6
SHEET 1 A 3 ARG A 312 HIS A 317 0
SHEET 2 A 3 THR A 385 TYR A 392 -1 N ALA A 390 O ARG A 312
SHEET 3 A 3 ASP A 357 VAL A 362 -1 N SER A 361 O ILE A 389
SHEET 1 B 2 SER A 404 VAL A 406 0
SHEET 2 B 2 ILE A 412 THR A 414 -1 N VAL A 413 O ARG A 405
SHEET 1 C 2 PHE A 325 GLY A 329 0
SHEET 2 C 2 ILE A 336 ILE A 341 -1 N PHE A 340 O ASN A 326
SITE 1 PEP 9 GLY A 322 LEU A 323 GLY A 324 PHE A 325
SITE 2 PEP 9 ASN A 326 ILE A 327 SER A 339 HIS A 372
SITE 3 PEP 9 LEU A 379
CRYST1 89.340 89.340 89.340 90.00 90.00 90.00 P 41 3 2 24
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 0.011193 0.000000 0.000000 0.00000
SCALE2 0.000000 0.011193 0.000000 0.00000
SCALE3 0.000000 0.000000 0.011193 0.00000
ATOM 1 N PHE A 301 60.491 64.723 43.937 1.00 46.74 N
ATOM 2 CA PHE A 301 59.665 65.467 44.936 1.00 47.04 C
ATOM 3 C PHE A 301 58.206 65.030 44.972 1.00 47.68 C
ATOM 4 O PHE A 301 57.855 64.059 45.638 1.00 48.40 O
ATOM 5 CB PHE A 301 59.738 66.973 44.672 1.00 47.19 C
ATOM 6 N LEU A 302 57.353 65.771 44.273 1.00 47.77 N
ATOM 7 CA LEU A 302 55.930 65.460 44.229 1.00 48.13 C
ATOM 8 C LEU A 302 55.710 63.975 43.957 1.00 48.63 C
ATOM 9 O LEU A 302 54.909 63.324 44.631 1.00 47.21 O
ATOM 10 CB LEU A 302 55.241 66.279 43.132 1.00 49.52 C
ATOM 11 CG LEU A 302 55.502 67.789 43.077 1.00 49.38 C
ATOM 12 CD1 LEU A 302 54.858 68.380 41.824 1.00 50.42 C
ATOM 13 CD2 LEU A 302 54.940 68.446 44.321 1.00 48.37 C
ATOM 14 N GLY A 303 56.440 63.455 42.969 1.00 49.39 N
ATOM 15 CA GLY A 303 56.331 62.061 42.559 1.00 49.20 C
ATOM 16 C GLY A 303 56.369 60.996 43.638 1.00 48.54 C
ATOM 17 O GLY A 303 56.195 59.806 43.359 1.00 47.23 O
ATOM 18 N GLU A 304 56.593 61.415 44.874 1.00 48.36 N
ATOM 19 CA GLU A 304 56.648 60.478 45.980 1.00 48.84 C
ATOM 20 C GLU A 304 55.431 60.652 46.881 1.00 46.67 C
ATOM 21 O GLU A 304 55.248 59.915 47.850 1.00 48.06 O
ATOM 22 CB GLU A 304 57.956 60.686 46.741 1.00 54.47 C
ATOM 23 CG GLU A 304 59.160 60.631 45.800 1.00 59.72 C
ATOM 24 CD GLU A 304 60.461 61.060 46.443 1.00 63.78 C
ATOM 25 OE1 GLU A 304 60.424 61.766 47.476 1.00 65.46 O
ATOM 26 OE2 GLU A 304 61.527 60.688 45.905 1.00 65.83 O
ATOM 27 N GLU A 305 54.594 61.628 46.540 1.00 40.78 N
ATOM 28 CA GLU A 305 53.376 61.897 47.293 1.00 36.71 C
ATOM 29 C GLU A 305 52.269 61.054 46.686 1.00 32.98 C
ATOM 30 O GLU A 305 52.228 60.858 45.471 1.00 30.51 O
ATOM 31 CB GLU A 305 53.003 63.375 47.193 1.00 38.76 C
ATOM 32 CG GLU A 305 54.152 64.325 47.471 1.00 40.45 C
ATOM 33 CD GLU A 305 53.715 65.772 47.470 1.00 40.61 C
ATOM 34 OE1 GLU A 305 52.703 66.088 46.808 1.00 39.25 O
ATOM 35 OE2 GLU A 305 54.386 66.591 48.133 1.00 44.78 O
ATOM 36 N ASP A 306 51.368 60.562 47.525 1.00 28.60 N
ATOM 37 CA ASP A 306 50.281 59.726 47.039 1.00 30.37 C
ATOM 38 C ASP A 306 49.301 60.508 46.176 1.00 28.08 C
ATOM 39 O ASP A 306 48.973 61.653 46.478 1.00 26.38 O
ATOM 40 CB ASP A 306 49.538 59.092 48.217 1.00 34.12 C
ATOM 41 CG ASP A 306 50.437 58.203 49.064 1.00 39.04 C
ATOM 42 OD1 ASP A 306 51.441 57.671 48.530 1.00 36.45 O
ATOM 43 OD2 ASP A 306 50.138 58.040 50.269 1.00 41.96 O
ATOM 44 N ILE A 307 48.847 59.886 45.093 1.00 25.30 N
ATOM 45 CA ILE A 307 47.884 60.523 44.205 1.00 21.89 C
ATOM 46 C ILE A 307 46.501 60.413 44.863 1.00 20.31 C
ATOM 47 O ILE A 307 46.085 59.332 45.267 1.00 17.92 O
ATOM 48 CB ILE A 307 47.872 59.829 42.817 1.00 21.13 C
ATOM 49 CG1 ILE A 307 49.250 59.977 42.157 1.00 21.72 C
ATOM 50 CG2 ILE A 307 46.796 60.448 41.924 1.00 18.43 C
ATOM 51 CD1 ILE A 307 49.413 59.214 40.854 1.00 23.93 C
ATOM 52 N PRO A 308 45.783 61.542 45.002 1.00 18.93 N
ATOM 53 CA PRO A 308 44.453 61.495 45.625 1.00 18.88 C
ATOM 54 C PRO A 308 43.543 60.460 44.966 1.00 17.94 C
ATOM 55 O PRO A 308 43.438 60.403 43.741 1.00 13.21 O
ATOM 56 CB PRO A 308 43.934 62.923 45.465 1.00 18.25 C
ATOM 57 CG PRO A 308 45.185 63.758 45.363 1.00 16.52 C
ATOM 58 CD PRO A 308 46.162 62.911 44.610 1.00 15.24 C
ATOM 59 N ARG A 309 42.886 59.643 45.785 1.00 16.37 N
ATOM 60 CA ARG A 309 42.015 58.605 45.252 1.00 15.10 C
ATOM 61 C ARG A 309 40.523 58.894 45.404 1.00 15.59 C
ATOM 62 O ARG A 309 39.683 58.084 45.006 1.00 15.12 O
ATOM 63 CB ARG A 309 42.380 57.253 45.881 1.00 16.26 C
ATOM 64 CG ARG A 309 43.570 56.588 45.190 1.00 17.86 C
ATOM 65 CD ARG A 309 44.106 55.425 45.990 1.00 16.83 C
ATOM 66 NE ARG A 309 45.320 54.873 45.394 1.00 17.91 N
ATOM 67 CZ ARG A 309 45.346 53.855 44.538 1.00 20.17 C
ATOM 68 NH1 ARG A 309 44.219 53.270 44.159 1.00 20.06 N
ATOM 69 NH2 ARG A 309 46.500 53.407 44.064 1.00 21.33 N
ATOM 70 N GLU A 310 40.190 60.052 45.968 1.00 16.80 N
ATOM 71 CA GLU A 310 38.781 60.422 46.120 1.00 18.33 C
ATOM 72 C GLU A 310 38.282 61.093 44.827 1.00 16.50 C
ATOM 73 O GLU A 310 39.079 61.588 44.030 1.00 14.19 O
ATOM 74 CB GLU A 310 38.593 61.349 47.327 1.00 19.63 C
ATOM 75 CG GLU A 310 38.634 62.855 47.055 1.00 30.81 C
ATOM 76 CD GLU A 310 38.303 63.671 48.316 1.00 39.26 C
ATOM 77 OE1 GLU A 310 38.866 63.368 49.401 1.00 45.57 O
ATOM 78 OE2 GLU A 310 37.474 64.616 48.250 1.00 42.33 O
ATOM 79 N PRO A 311 36.953 61.087 44.599 1.00 15.93 N
ATOM 80 CA PRO A 311 36.424 61.714 43.380 1.00 13.50 C
ATOM 81 C PRO A 311 36.711 63.203 43.347 1.00 13.49 C
ATOM 82 O PRO A 311 36.789 63.853 44.393 1.00 16.15 O
ATOM 83 CB PRO A 311 34.920 61.432 43.424 1.00 14.51 C
ATOM 84 CG PRO A 311 34.695 60.524 44.560 1.00 15.67 C
ATOM 85 CD PRO A 311 35.905 60.500 45.439 1.00 14.21 C
ATOM 86 N ARG A 312 36.888 63.725 42.133 1.00 11.90 N
ATOM 87 CA ARG A 312 37.164 65.134 41.906 1.00 13.21 C
ATOM 88 C ARG A 312 36.256 65.675 40.808 1.00 13.50 C
ATOM 89 O ARG A 312 35.872 64.944 39.899 1.00 12.93 O
ATOM 90 CB ARG A 312 38.612 65.347 41.446 1.00 12.92 C
ATOM 91 CG ARG A 312 39.688 64.936 42.433 1.00 15.05 C
ATOM 92 CD ARG A 312 40.598 63.857 41.859 1.00 10.73 C
ATOM 93 NE ARG A 312 41.010 64.126 40.487 1.00 10.18 N
ATOM 94 CZ ARG A 312 41.123 63.187 39.556 1.00 12.03 C
ATOM 95 NH1 ARG A 312 40.844 61.926 39.855 1.00 11.50 N
ATOM 96 NH2 ARG A 312 41.511 63.503 38.329 1.00 10.70 N
ATOM 97 N ARG A 313 35.906 66.955 40.891 1.00 13.84 N
ATOM 98 CA ARG A 313 35.106 67.556 39.831 1.00 15.73 C
ATOM 99 C ARG A 313 36.075 68.363 38.976 1.00 12.83 C
ATOM 100 O ARG A 313 36.901 69.103 39.495 1.00 14.36 O
ATOM 101 CB ARG A 313 34.028 68.479 40.380 1.00 17.02 C
ATOM 102 CG ARG A 313 33.237 69.167 39.271 1.00 19.80 C
ATOM 103 CD ARG A 313 32.370 70.290 39.806 1.00 21.89 C
ATOM 104 NE ARG A 313 31.368 69.799 40.747 1.00 22.79 N
ATOM 105 CZ ARG A 313 31.498 69.834 42.071 1.00 22.23 C
ATOM 106 NH1 ARG A 313 32.593 70.338 42.627 1.00 19.04 N
ATOM 107 NH2 ARG A 313 30.523 69.369 42.841 1.00 22.82 N
ATOM 108 N ILE A 314 35.991 68.192 37.665 1.00 15.57 N
ATOM 109 CA ILE A 314 36.863 68.917 36.750 1.00 16.15 C
ATOM 110 C ILE A 314 35.982 69.601 35.717 1.00 15.41 C
ATOM 111 O ILE A 314 35.194 68.950 35.033 1.00 17.90 O
ATOM 112 CB ILE A 314 37.848 67.967 36.015 1.00 15.89 C
ATOM 113 CG1 ILE A 314 38.748 67.255 37.028 1.00 15.48 C
ATOM 114 CG2 ILE A 314 38.691 68.759 35.021 1.00 13.51 C
ATOM 115 CD1 ILE A 314 38.258 65.861 37.431 1.00 16.31 C
ATOM 116 N VAL A 315 36.098 70.918 35.624 1.00 16.89 N
ATOM 117 CA VAL A 315 35.310 71.661 34.656 1.00 18.70 C
ATOM 118 C VAL A 315 36.225 72.114 33.536 1.00 17.83 C
ATOM 119 O VAL A 315 37.137 72.914 33.734 1.00 18.32 O
ATOM 120 CB VAL A 315 34.629 72.879 35.293 1.00 20.18 C
ATOM 121 CG1 VAL A 315 33.876 73.676 34.229 1.00 22.50 C
ATOM 122 CG2 VAL A 315 33.672 72.414 36.380 1.00 14.77 C
ATOM 123 N ILE A 316 35.974 71.581 32.352 1.00 19.96 N
ATOM 124 CA ILE A 316 36.777 71.904 31.194 1.00 19.29 C
ATOM 125 C ILE A 316 35.996 72.772 30.221 1.00 18.88 C
ATOM 126 O ILE A 316 34.867 72.454 29.852 1.00 17.02 O
ATOM 127 CB ILE A 316 37.230 70.618 30.484 1.00 20.46 C
ATOM 128 CG1 ILE A 316 38.185 69.844 31.399 1.00 18.40 C
ATOM 129 CG2 ILE A 316 37.874 70.954 29.144 1.00 19.54 C
ATOM 130 CD1 ILE A 316 38.967 68.766 30.696 1.00 18.49 C
ATOM 131 N HIS A 317 36.602 73.886 29.830 1.00 18.87 N
ATOM 132 CA HIS A 317 35.985 74.788 28.874 1.00 23.24 C
ATOM 133 C HIS A 317 36.733 74.548 27.570 1.00 21.52 C
ATOM 134 O HIS A 317 37.865 74.996 27.407 1.00 26.66 O
ATOM 135 CB HIS A 317 36.145 76.234 29.347 1.00 25.70 C
ATOM 136 CG HIS A 317 35.611 76.466 30.725 1.00 27.94 C
ATOM 137 ND1 HIS A 317 34.264 76.471 31.006 1.00 26.80 N
ATOM 138 CD2 HIS A 317 36.248 76.657 31.905 1.00 28.12 C
ATOM 139 CE1 HIS A 317 34.090 76.652 32.306 1.00 29.48 C
ATOM 140 NE2 HIS A 317 35.277 76.768 32.871 1.00 30.52 N
ATOM 141 N ARG A 318 36.107 73.826 26.647 1.00 20.49 N
ATOM 142 CA ARG A 318 36.759 73.500 25.382 1.00 19.81 C
ATOM 143 C ARG A 318 36.070 74.076 24.158 1.00 18.16 C
ATOM 144 O ARG A 318 36.464 73.791 23.026 1.00 19.50 O
ATOM 145 CB ARG A 318 36.864 71.980 25.234 1.00 16.72 C
ATOM 146 CG ARG A 318 35.588 71.242 25.601 1.00 14.85 C
ATOM 147 CD ARG A 318 34.648 71.160 24.410 1.00 13.51 C
ATOM 148 NE ARG A 318 33.597 70.169 24.611 1.00 15.66 N
ATOM 149 CZ ARG A 318 33.608 68.944 24.091 1.00 17.94 C
ATOM 150 NH1 ARG A 318 34.622 68.544 23.334 1.00 18.48 N
ATOM 151 NH2 ARG A 318 32.608 68.108 24.346 1.00 18.05 N
ATOM 152 N GLY A 319 35.044 74.886 24.379 1.00 17.11 N
ATOM 153 CA GLY A 319 34.343 75.466 23.251 1.00 19.37 C
ATOM 154 C GLY A 319 33.942 74.392 22.261 1.00 19.56 C
ATOM 155 O GLY A 319 33.214 73.465 22.613 1.00 19.45 O
ATOM 156 N SER A 320 34.420 74.501 21.027 1.00 20.48 N
ATOM 157 CA SER A 320 34.067 73.521 20.007 1.00 22.84 C
ATOM 158 C SER A 320 35.264 72.720 19.540 1.00 20.94 C
ATOM 159 O SER A 320 35.435 72.455 18.350 1.00 21.21 O
ATOM 160 CB SER A 320 33.402 74.207 18.812 1.00 22.02 C
ATOM 161 OG SER A 320 31.999 74.246 18.986 1.00 21.22 O
ATOM 162 N THR A 321 36.094 72.325 20.494 1.00 22.15 N
ATOM 163 CA THR A 321 37.271 71.539 20.183 1.00 18.92 C
ATOM 164 C THR A 321 37.227 70.252 21.000 1.00 16.89 C
ATOM 165 O THR A 321 36.437 70.127 21.937 1.00 15.13 O
ATOM 166 CB THR A 321 38.562 72.342 20.486 1.00 24.16 C
ATOM 167 OG1 THR A 321 38.596 72.714 21.873 1.00 23.85 O
ATOM 168 CG2 THR A 321 38.604 73.611 19.629 1.00 21.26 C
ATOM 169 N GLY A 322 38.052 69.284 20.625 1.00 16.33 N
ATOM 170 CA GLY A 322 38.077 68.031 21.349 1.00 15.88 C
ATOM 171 C GLY A 322 38.557 68.252 22.771 1.00 16.25 C
ATOM 172 O GLY A 322 39.191 69.261 23.067 1.00 16.85 O
ATOM 173 N LEU A 323 38.250 67.309 23.655 1.00 16.16 N
ATOM 174 CA LEU A 323 38.665 67.403 25.048 1.00 14.78 C
ATOM 175 C LEU A 323 40.160 67.124 25.149 1.00 13.20 C
ATOM 176 O LEU A 323 40.832 67.593 26.069 1.00 14.11 O
ATOM 177 CB LEU A 323 37.874 66.409 25.899 1.00 12.62 C
ATOM 178 CG LEU A 323 36.451 66.895 26.183 1.00 14.27 C
ATOM 179 CD1 LEU A 323 35.521 65.729 26.412 1.00 10.09 C
ATOM 180 CD2 LEU A 323 36.473 67.807 27.391 1.00 15.83 C
ATOM 181 N GLY A 324 40.681 66.359 24.196 1.00 10.17 N
ATOM 182 CA GLY A 324 42.097 66.074 24.204 1.00 8.68 C
ATOM 183 C GLY A 324 42.540 64.898 25.045 1.00 10.96 C
ATOM 184 O GLY A 324 43.581 64.961 25.711 1.00 12.00 O
ATOM 185 N PHE A 325 41.738 63.838 25.060 1.00 12.66 N
ATOM 186 CA PHE A 325 42.118 62.620 25.768 1.00 12.59 C
ATOM 187 C PHE A 325 41.445 61.386 25.188 1.00 12.59 C
ATOM 188 O PHE A 325 40.454 61.480 24.460 1.00 11.46 O
ATOM 189 CB PHE A 325 41.900 62.733 27.289 1.00 11.85 C
ATOM 190 CG PHE A 325 40.463 62.819 27.720 1.00 13.45 C
ATOM 191 CD1 PHE A 325 39.692 61.671 27.862 1.00 12.91 C
ATOM 192 CD2 PHE A 325 39.914 64.042 28.094 1.00 14.38 C
ATOM 193 CE1 PHE A 325 38.389 61.737 28.376 1.00 12.50 C
ATOM 194 CE2 PHE A 325 38.615 64.119 28.608 1.00 14.20 C
ATOM 195 CZ PHE A 325 37.855 62.960 28.752 1.00 11.37 C
ATOM 196 N ASN A 326 42.039 60.236 25.484 1.00 15.98 N
ATOM 197 CA ASN A 326 41.581 58.931 25.006 1.00 18.26 C
ATOM 198 C ASN A 326 40.897 58.159 26.133 1.00 14.20 C
ATOM 199 O ASN A 326 41.284 58.273 27.294 1.00 11.07 O
ATOM 200 CB ASN A 326 42.783 58.099 24.532 1.00 20.99 C
ATOM 201 CG ASN A 326 43.110 58.296 23.064 1.00 23.08 C
ATOM 202 OD1 ASN A 326 42.847 59.347 22.482 1.00 20.96 O
ATOM 203 ND2 ASN A 326 43.699 57.273 22.460 1.00 28.01 N
ATOM 204 N ILE A 327 39.889 57.372 25.783 1.00 13.72 N
ATOM 205 CA ILE A 327 39.198 56.557 26.771 1.00 14.13 C
ATOM 206 C ILE A 327 39.232 55.100 26.330 1.00 12.55 C
ATOM 207 O ILE A 327 39.238 54.807 25.137 1.00 13.43 O
ATOM 208 CB ILE A 327 37.703 56.973 26.954 1.00 16.22 C
ATOM 209 CG1 ILE A 327 36.951 56.879 25.621 1.00 14.36 C
ATOM 210 CG2 ILE A 327 37.616 58.378 27.532 1.00 16.00 C
ATOM 211 CD1 ILE A 327 35.449 56.733 25.784 1.00 11.90 C
ATOM 212 N ILE A 328 39.289 54.203 27.308 1.00 12.94 N
ATOM 213 CA ILE A 328 39.273 52.761 27.077 1.00 14.88 C
ATOM 214 C ILE A 328 38.246 52.197 28.065 1.00 16.30 C
ATOM 215 O ILE A 328 37.899 52.854 29.048 1.00 12.07 O
ATOM 216 CB ILE A 328 40.643 52.100 27.358 1.00 15.57 C
ATOM 217 CG1 ILE A 328 41.048 52.333 28.811 1.00 18.59 C
ATOM 218 CG2 ILE A 328 41.689 52.671 26.453 1.00 16.98 C
ATOM 219 CD1 ILE A 328 42.482 51.993 29.097 1.00 27.69 C
ATOM 220 N GLY A 329 37.769 50.985 27.803 1.00 18.81 N
ATOM 221 CA GLY A 329 36.783 50.366 28.669 1.00 20.74 C
ATOM 222 C GLY A 329 35.371 50.490 28.120 1.00 19.78 C
ATOM 223 O GLY A 329 35.171 50.885 26.970 1.00 19.50 O
ATOM 224 N GLY A 330 34.384 50.171 28.947 1.00 24.57 N
ATOM 225 CA GLY A 330 33.008 50.253 28.503 1.00 29.06 C
ATOM 226 C GLY A 330 32.507 48.914 28.009 1.00 34.01 C
ATOM 227 O GLY A 330 31.429 48.823 27.416 1.00 37.98 O
ATOM 228 N GLU A 331 33.297 47.873 28.231 1.00 38.49 N
ATOM 229 CA GLU A 331 32.897 46.532 27.828 1.00 44.72 C
ATOM 230 C GLU A 331 32.596 45.694 29.065 1.00 44.82 C
ATOM 231 O GLU A 331 33.464 45.454 29.905 1.00 47.68 O
ATOM 232 CB GLU A 331 33.993 45.870 26.989 1.00 46.07 C
ATOM 233 CG GLU A 331 33.994 46.358 25.559 1.00 53.49 C
ATOM 234 CD GLU A 331 35.146 45.830 24.740 1.00 61.07 C
ATOM 235 OE1 GLU A 331 35.843 44.892 25.203 1.00 65.76 O
ATOM 236 OE2 GLU A 331 35.357 46.356 23.616 1.00 64.90 O
ATOM 237 N ASP A 332 31.342 45.293 29.202 1.00 46.50 N
ATOM 238 CA ASP A 332 30.945 44.453 30.318 1.00 48.45 C
ATOM 239 C ASP A 332 31.215 45.014 31.711 1.00 48.79 C
ATOM 240 O ASP A 332 31.824 44.332 32.539 1.00 51.57 O
ATOM 241 CB ASP A 332 31.631 43.102 30.191 1.00 48.50 C
ATOM 242 N GLY A 333 30.788 46.243 31.977 1.00 48.90 N
ATOM 243 CA GLY A 333 30.996 46.798 33.307 1.00 48.17 C
ATOM 244 C GLY A 333 32.223 47.674 33.474 1.00 47.11 C
ATOM 245 O GLY A 333 32.091 48.872 33.718 1.00 50.84 O
ATOM 246 N GLU A 334 33.404 47.076 33.353 1.00 45.31 N
ATOM 247 CA GLU A 334 34.694 47.770 33.473 1.00 43.63 C
ATOM 248 C GLU A 334 34.710 49.245 33.917 1.00 39.13 C
ATOM 249 O GLU A 334 35.335 49.599 34.922 1.00 40.54 O
ATOM 250 CB GLU A 334 35.466 47.660 32.150 1.00 47.36 C
ATOM 251 CG GLU A 334 35.988 46.272 31.857 1.00 57.08 C
ATOM 252 CD GLU A 334 36.680 45.647 33.052 1.00 65.38 C
ATOM 253 OE1 GLU A 334 37.294 46.399 33.855 1.00 68.10 O
ATOM 254 OE2 GLU A 334 36.613 44.398 33.198 1.00 71.28 O
ATOM 255 N GLY A 335 34.042 50.112 33.164 1.00 31.77 N
ATOM 256 CA GLY A 335 34.038 51.524 33.501 1.00 22.95 C
ATOM 257 C GLY A 335 34.790 52.248 32.399 1.00 19.05 C
ATOM 258 O GLY A 335 35.392 51.591 31.546 1.00 15.92 O
ATOM 259 N ILE A 336 34.763 53.580 32.406 1.00 15.28 N
ATOM 260 CA ILE A 336 35.446 54.372 31.379 1.00 14.99 C
ATOM 261 C ILE A 336 36.695 55.027 31.966 1.00 11.80 C
ATOM 262 O ILE A 336 36.610 55.815 32.907 1.00 12.20 O
ATOM 263 CB ILE A 336 34.503 55.471 30.797 1.00 15.26 C
ATOM 264 CG1 ILE A 336 33.250 54.827 30.175 1.00 14.11 C
ATOM 265 CG2 ILE A 336 35.251 56.312 29.762 1.00 13.09 C
ATOM 266 CD1 ILE A 336 33.536 53.764 29.130 1.00 12.36 C
ATOM 267 N PHE A 337 37.858 54.695 31.411 1.00 12.24 N
ATOM 268 CA PHE A 337 39.117 55.245 31.915 1.00 12.77 C
ATOM 269 C PHE A 337 39.887 56.073 30.896 1.00 11.75 C
ATOM 270 O PHE A 337 39.801 55.832 29.689 1.00 11.63 O
ATOM 271 CB PHE A 337 40.036 54.120 32.408 1.00 9.54 C
ATOM 272 CG PHE A 337 39.397 53.212 33.413 1.00 13.93 C
ATOM 273 CD1 PHE A 337 38.422 52.298 33.026 1.00 14.14 C
ATOM 274 CD2 PHE A 337 39.761 53.279 34.757 1.00 16.95 C
ATOM 275 CE1 PHE A 337 37.811 51.465 33.963 1.00 14.24 C
ATOM 276 CE2 PHE A 337 39.159 52.453 35.699 1.00 14.83 C
ATOM 277 CZ PHE A 337 38.180 51.544 35.300 1.00 16.41 C
ATOM 278 N ILE A 338 40.637 57.051 31.399 1.00 8.82 N
ATOM 279 CA ILE A 338 41.461 57.885 30.544 1.00 12.07 C
ATOM 280 C ILE A 338 42.756 57.108 30.310 1.00 12.41 C
ATOM 281 O ILE A 338 43.428 56.705 31.259 1.00 14.05 O
ATOM 282 CB ILE A 338 41.788 59.227 31.208 1.00 13.80 C
ATOM 283 CG1 ILE A 338 40.499 60.040 31.390 1.00 16.31 C
ATOM 284 CG2 ILE A 338 42.811 59.982 30.356 1.00 13.32 C
ATOM 285 CD1 ILE A 338 40.707 61.452 31.927 1.00 13.29 C
ATOM 286 N SER A 339 43.098 56.885 29.049 1.00 9.36 N
ATOM 287 CA SER A 339 44.297 56.135 28.727 1.00 10.88 C
ATOM 288 C SER A 339 45.401 57.022 28.200 1.00 13.10 C
ATOM 289 O SER A 339 46.554 56.597 28.104 1.00 14.09 O
ATOM 290 CB SER A 339 43.986 55.085 27.664 1.00 13.04 C
ATOM 291 OG SER A 339 43.514 55.706 26.481 1.00 12.83 O
ATOM 292 N PHE A 340 45.049 58.254 27.860 1.00 12.55 N
ATOM 293 CA PHE A 340 46.020 59.170 27.275 1.00 11.75 C
ATOM 294 C PHE A 340 45.534 60.613 27.340 1.00 8.95 C
ATOM 295 O PHE A 340 44.357 60.895 27.120 1.00 9.69 O
ATOM 296 CB PHE A 340 46.253 58.734 25.811 1.00 13.24 C
ATOM 297 CG PHE A 340 47.120 59.665 25.001 1.00 10.45 C
ATOM 298 CD1 PHE A 340 46.596 60.838 24.456 1.00 12.05 C
ATOM 299 CD2 PHE A 340 48.442 59.324 24.717 1.00 14.86 C
ATOM 300 CE1 PHE A 340 47.377 61.655 23.642 1.00 11.97 C
ATOM 301 CE2 PHE A 340 49.238 60.140 23.899 1.00 14.05 C
ATOM 302 CZ PHE A 340 48.701 61.304 23.361 1.00 10.29 C
ATOM 303 N ILE A 341 46.450 61.518 27.661 1.00 8.14 N
ATOM 304 CA ILE A 341 46.120 62.930 27.712 1.00 9.23 C
ATOM 305 C ILE A 341 47.000 63.606 26.669 1.00 8.59 C
ATOM 306 O ILE A 341 48.223 63.500 26.703 1.00 10.00 O
ATOM 307 CB ILE A 341 46.378 63.527 29.109 1.00 8.49 C
ATOM 308 CG1 ILE A 341 45.722 62.634 30.177 1.00 12.43 C
ATOM 309 CG2 ILE A 341 45.917 64.989 29.142 1.00 11.02 C
ATOM 310 CD1 ILE A 341 44.646 63.284 31.039 1.00 14.65 C
ATOM 311 N LEU A 342 46.361 64.279 25.721 1.00 10.31 N
ATOM 312 CA LEU A 342 47.065 64.950 24.641 1.00 8.74 C
ATOM 313 C LEU A 342 47.755 66.223 25.099 1.00 10.56 C
ATOM 314 O LEU A 342 47.147 67.070 25.747 1.00 11.56 O
ATOM 315 CB LEU A 342 46.079 65.278 23.521 1.00 10.69 C
ATOM 316 CG LEU A 342 46.607 66.136 22.376 1.00 15.55 C
ATOM 317 CD1 LEU A 342 47.560 65.304 21.517 1.00 15.24 C
ATOM 318 CD2 LEU A 342 45.444 66.647 21.553 1.00 13.96 C
ATOM 319 N ALA A 343 49.030 66.357 24.754 1.00 13.86 N
ATOM 320 CA ALA A 343 49.792 67.547 25.118 1.00 15.26 C
ATOM 321 C ALA A 343 49.189 68.779 24.447 1.00 15.26 C
ATOM 322 O ALA A 343 49.004 68.806 23.226 1.00 14.40 O
ATOM 323 CB ALA A 343 51.248 67.386 24.690 1.00 14.86 C
ATOM 324 N GLY A 344 48.875 69.790 25.249 1.00 13.89 N
ATOM 325 CA GLY A 344 48.321 71.013 24.702 1.00 12.93 C
ATOM 326 C GLY A 344 46.813 71.047 24.604 1.00 14.71 C
ATOM 327 O GLY A 344 46.239 72.102 24.342 1.00 14.71 O
ATOM 328 N GLY A 345 46.164 69.907 24.807 1.00 12.42 N
ATOM 329 CA GLY A 345 44.717 69.869 24.729 1.00 14.06 C
ATOM 330 C GLY A 345 44.034 70.461 25.956 1.00 13.40 C
ATOM 331 O GLY A 345 44.691 70.726 26.960 1.00 12.78 O
ATOM 332 N PRO A 346 42.716 70.716 25.888 1.00 13.39 N
ATOM 333 CA PRO A 346 41.964 71.279 27.015 1.00 13.69 C
ATOM 334 C PRO A 346 42.119 70.466 28.299 1.00 13.67 C
ATOM 335 O PRO A 346 42.243 71.033 29.381 1.00 16.01 O
ATOM 336 CB PRO A 346 40.517 71.286 26.519 1.00 15.27 C
ATOM 337 CG PRO A 346 40.633 71.318 25.033 1.00 16.21 C
ATOM 338 CD PRO A 346 41.863 70.527 24.700 1.00 14.40 C
ATOM 339 N ALA A 347 42.106 69.142 28.186 1.00 13.11 N
ATOM 340 CA ALA A 347 42.251 68.286 29.368 1.00 15.75 C
ATOM 341 C ALA A 347 43.632 68.467 30.011 1.00 15.54 C
ATOM 342 O ALA A 347 43.767 68.472 31.233 1.00 17.98 O
ATOM 343 CB ALA A 347 42.028 66.815 28.992 1.00 13.50 C
ATOM 344 N ASP A 348 44.657 68.604 29.179 1.00 16.82 N
ATOM 345 CA ASP A 348 46.016 68.817 29.667 1.00 17.75 C
ATOM 346 C ASP A 348 46.096 70.184 30.375 1.00 19.21 C
ATOM 347 O ASP A 348 46.566 70.284 31.512 1.00 17.79 O
ATOM 348 CB ASP A 348 46.991 68.772 28.484 1.00 14.89 C
ATOM 349 CG ASP A 348 48.430 69.029 28.892 1.00 16.16 C
ATOM 350 OD1 ASP A 348 48.811 68.732 30.045 1.00 14.85 O
ATOM 351 OD2 ASP A 348 49.188 69.530 28.046 1.00 17.67 O
ATOM 352 N LEU A 349 45.612 71.224 29.699 1.00 17.94 N
ATOM 353 CA LEU A 349 45.625 72.583 30.232 1.00 21.74 C
ATOM 354 C LEU A 349 44.802 72.742 31.514 1.00 23.67 C
ATOM 355 O LEU A 349 44.913 73.749 32.210 1.00 26.00 O
ATOM 356 CB LEU A 349 45.129 73.566 29.164 1.00 23.96 C
ATOM 357 CG LEU A 349 45.874 73.570 27.821 1.00 27.19 C
ATOM 358 CD1 LEU A 349 45.481 74.803 27.029 1.00 30.00 C
ATOM 359 CD2 LEU A 349 47.374 73.548 28.042 1.00 26.65 C
ATOM 360 N SER A 350 43.966 71.756 31.819 1.00 25.14 N
ATOM 361 CA SER A 350 43.166 71.787 33.038 1.00 25.11 C
ATOM 362 C SER A 350 44.067 71.324 34.183 1.00 25.71 C
ATOM 363 O SER A 350 43.875 71.704 35.345 1.00 25.29 O
ATOM 364 CB SER A 350 41.966 70.843 32.916 1.00 24.46 C
ATOM 365 OG SER A 350 42.257 69.562 33.461 1.00 24.35 O
ATOM 366 N GLY A 351 45.055 70.501 33.830 1.00 24.86 N
ATOM 367 CA GLY A 351 45.997 69.965 34.795 1.00 19.53 C
ATOM 368 C GLY A 351 45.334 69.177 35.905 1.00 18.94 C
ATOM 369 O GLY A 351 45.957 68.915 36.930 1.00 19.72 O
ATOM 370 N GLU A 352 44.079 68.783 35.708 1.00 17.06 N
ATOM 371 CA GLU A 352 43.350 68.045 36.734 1.00 17.95 C
ATOM 372 C GLU A 352 42.970 66.612 36.379 1.00 18.97 C
ATOM 373 O GLU A 352 42.312 65.932 37.166 1.00 17.08 O
ATOM 374 CB GLU A 352 42.074 68.788 37.110 1.00 19.10 C
ATOM 375 CG GLU A 352 42.292 70.131 37.747 1.00 25.17 C
ATOM 376 CD GLU A 352 41.013 70.939 37.793 1.00 31.33 C
ATOM 377 OE1 GLU A 352 40.708 71.627 36.797 1.00 33.99 O
ATOM 378 OE2 GLU A 352 40.307 70.885 38.822 1.00 37.15 O
ATOM 379 N LEU A 353 43.363 66.160 35.195 1.00 19.39 N
ATOM 380 CA LEU A 353 43.054 64.801 34.760 1.00 17.30 C
ATOM 381 C LEU A 353 44.342 64.072 34.430 1.00 16.86 C
ATOM 382 O LEU A 353 45.352 64.699 34.118 1.00 18.17 O
ATOM 383 CB LEU A 353 42.167 64.823 33.516 1.00 18.00 C
ATOM 384 CG LEU A 353 40.744 65.370 33.647 1.00 15.10 C
ATOM 385 CD1 LEU A 353 40.182 65.636 32.254 1.00 17.34 C
ATOM 386 CD2 LEU A 353 39.867 64.371 34.388 1.00 16.66 C
ATOM 387 N ARG A 354 44.304 62.747 34.492 1.00 15.49 N
ATOM 388 CA ARG A 354 45.478 61.945 34.183 1.00 15.04 C
ATOM 389 C ARG A 354 45.100 60.528 33.771 1.00 15.46 C
ATOM 390 O ARG A 354 43.981 60.063 34.012 1.00 12.34 O
ATOM 391 CB ARG A 354 46.413 61.890 35.389 1.00 16.16 C
ATOM 392 CG ARG A 354 46.006 60.876 36.439 1.00 17.70 C
ATOM 393 CD ARG A 354 47.168 60.533 37.351 1.00 27.69 C
ATOM 394 NE ARG A 354 47.596 61.668 38.166 1.00 31.67 N
ATOM 395 CZ ARG A 354 48.864 62.048 38.309 1.00 37.68 C
ATOM 396 NH1 ARG A 354 49.837 61.385 37.686 1.00 36.80 N
ATOM 397 NH2 ARG A 354 49.164 63.092 39.074 1.00 35.54 N
ATOM 398 N LYS A 355 46.045 59.849 33.135 1.00 15.40 N
ATOM 399 CA LYS A 355 45.839 58.476 32.712 1.00 15.69 C
ATOM 400 C LYS A 355 45.558 57.666 33.978 1.00 14.46 C
ATOM 401 O LYS A 355 46.214 57.869 35.004 1.00 13.40 O
ATOM 402 CB LYS A 355 47.098 57.960 32.019 1.00 14.55 C
ATOM 403 CG LYS A 355 47.059 56.491 31.690 1.00 17.13 C
ATOM 404 CD LYS A 355 48.244 56.106 30.831 1.00 17.26 C
ATOM 405 CE LYS A 355 49.376 55.559 31.683 1.00 21.10 C
ATOM 406 NZ LYS A 355 50.278 54.668 30.889 1.00 26.31 N
ATOM 407 N GLY A 356 44.585 56.761 33.910 1.00 12.02 N
ATOM 408 CA GLY A 356 44.248 55.956 35.077 1.00 13.41 C
ATOM 409 C GLY A 356 42.997 56.463 35.775 1.00 11.90 C
ATOM 410 O GLY A 356 42.415 55.771 36.611 1.00 10.50 O
ATOM 411 N ASP A 357 42.590 57.683 35.427 1.00 11.22 N
ATOM 412 CA ASP A 357 41.395 58.307 35.979 1.00 8.99 C
ATOM 413 C ASP A 357 40.169 57.661 35.349 1.00 12.51 C
ATOM 414 O ASP A 357 40.137 57.426 34.138 1.00 11.87 O
ATOM 415 CB ASP A 357 41.355 59.794 35.628 1.00 10.59 C
ATOM 416 CG ASP A 357 41.975 60.675 36.686 1.00 9.14 C
ATOM 417 OD1 ASP A 357 42.145 60.229 37.837 1.00 8.93 O
ATOM 418 OD2 ASP A 357 42.293 61.836 36.356 1.00 14.55 O
ATOM 419 N GLN A 358 39.164 57.367 36.163 1.00 14.16 N
ATOM 420 CA GLN A 358 37.932 56.804 35.639 1.00 13.07 C
ATOM 421 C GLN A 358 36.962 57.970 35.551 1.00 12.07 C
ATOM 422 O GLN A 358 36.907 58.801 36.459 1.00 10.43 O
ATOM 423 CB GLN A 358 37.350 55.736 36.567 1.00 14.39 C
ATOM 424 CG GLN A 358 36.089 55.091 35.978 1.00 19.65 C
ATOM 425 CD GLN A 358 35.327 54.210 36.961 1.00 19.32 C
ATOM 426 OE1 GLN A 358 35.750 54.001 38.099 1.00 13.89 O
ATOM 427 NE2 GLN A 358 34.191 53.689 36.514 1.00 16.98 N
ATOM 428 N ILE A 359 36.216 58.050 34.453 1.00 12.70 N
ATOM 429 CA ILE A 359 35.240 59.123 34.296 1.00 13.71 C
ATOM 430 C ILE A 359 33.939 58.617 34.895 1.00 11.02 C
ATOM 431 O ILE A 359 33.262 57.781 34.297 1.00 13.53 O
ATOM 432 CB ILE A 359 34.968 59.473 32.815 1.00 17.06 C
ATOM 433 CG1 ILE A 359 36.286 59.629 32.034 1.00 15.88 C
ATOM 434 CG2 ILE A 359 34.107 60.734 32.750 1.00 15.26 C
ATOM 435 CD1 ILE A 359 37.108 60.844 32.415 1.00 19.25 C
ATOM 436 N LEU A 360 33.597 59.116 36.077 1.00 12.57 N
ATOM 437 CA LEU A 360 32.382 58.689 36.753 1.00 13.57 C
ATOM 438 C LEU A 360 31.139 59.288 36.108 1.00 14.87 C
ATOM 439 O LEU A 360 30.075 58.664 36.077 1.00 15.90 O
ATOM 440 CB LEU A 360 32.452 59.069 38.230 1.00 14.94 C
ATOM 441 CG LEU A 360 33.629 58.457 39.001 1.00 12.51 C
ATOM 442 CD1 LEU A 360 33.340 58.524 40.491 1.00 14.64 C
ATOM 443 CD2 LEU A 360 33.856 57.015 38.564 1.00 14.94 C
ATOM 444 N SER A 361 31.280 60.496 35.577 1.00 16.97 N
ATOM 445 CA SER A 361 30.157 61.152 34.922 1.00 16.86 C
ATOM 446 C SER A 361 30.601 62.371 34.126 1.00 16.92 C
ATOM 447 O SER A 361 31.684 62.915 34.343 1.00 14.15 O
ATOM 448 CB SER A 361 29.114 61.576 35.958 1.00 14.21 C
ATOM 449 OG SER A 361 29.564 62.699 36.691 1.00 19.61 O
ATOM 450 N VAL A 362 29.751 62.773 33.190 1.00 15.74 N
ATOM 451 CA VAL A 362 29.993 63.942 32.365 1.00 18.66 C
ATOM 452 C VAL A 362 28.711 64.774 32.415 1.00 18.84 C
ATOM 453 O VAL A 362 27.640 64.315 32.015 1.00 18.08 O
ATOM 454 CB VAL A 362 30.329 63.557 30.889 1.00 19.71 C
ATOM 455 CG1 VAL A 362 29.174 62.815 30.245 1.00 24.01 C
ATOM 456 CG2 VAL A 362 30.651 64.808 30.095 1.00 22.47 C
ATOM 457 N ASN A 363 28.817 65.988 32.942 1.00 18.33 N
ATOM 458 CA ASN A 363 27.661 66.867 33.045 1.00 19.63 C
ATOM 459 C ASN A 363 26.484 66.159 33.721 1.00 21.40 C
ATOM 460 O ASN A 363 25.359 66.179 33.218 1.00 21.79 O
ATOM 461 CB ASN A 363 27.246 67.352 31.651 1.00 20.86 C
ATOM 462 CG ASN A 363 28.251 68.313 31.042 1.00 21.20 C
ATOM 463 OD1 ASN A 363 29.212 68.716 31.693 1.00 22.32 O
ATOM 464 ND2 ASN A 363 28.032 68.683 29.785 1.00 20.10 N
ATOM 465 N GLY A 364 26.749 65.523 34.859 1.00 21.91 N
ATOM 466 CA GLY A 364 25.691 64.840 35.583 1.00 20.55 C
ATOM 467 C GLY A 364 25.321 63.459 35.074 1.00 21.12 C
ATOM 468 O GLY A 364 24.694 62.684 35.797 1.00 21.54 O
ATOM 469 N VAL A 365 25.695 63.136 33.840 1.00 19.93 N
ATOM 470 CA VAL A 365 25.379 61.823 33.293 1.00 19.08 C
ATOM 471 C VAL A 365 26.346 60.751 33.801 1.00 20.44 C
ATOM 472 O VAL A 365 27.547 60.783 33.522 1.00 18.40 O
ATOM 473 CB VAL A 365 25.408 61.837 31.758 1.00 17.84 C
ATOM 474 CG1 VAL A 365 24.892 60.511 31.217 1.00 15.43 C
ATOM 475 CG2 VAL A 365 24.560 62.983 31.248 1.00 21.64 C
ATOM 476 N ASP A 366 25.800 59.807 34.556 1.00 18.04 N
ATOM 477 CA ASP A 366 26.561 58.703 35.128 1.00 19.44 C
ATOM 478 C ASP A 366 27.154 57.841 34.015 1.00 20.23 C
ATOM 479 O ASP A 366 26.429 57.317 33.166 1.00 20.94 O
ATOM 480 CB ASP A 366 25.632 57.864 36.010 1.00 20.05 C
ATOM 481 CG ASP A 366 26.366 56.808 36.809 1.00 20.79 C
ATOM 482 OD1 ASP A 366 27.610 56.745 36.731 1.00 16.73 O
ATOM 483 OD2 ASP A 366 25.684 56.037 37.521 1.00 25.68 O
ATOM 484 N LEU A 367 28.475 57.697 34.015 1.00 18.10 N
ATOM 485 CA LEU A 367 29.138 56.895 32.996 1.00 15.06 C
ATOM 486 C LEU A 367 29.786 55.646 33.579 1.00 15.66 C
ATOM 487 O LEU A 367 30.475 54.917 32.873 1.00 16.78 O
ATOM 488 CB LEU A 367 30.209 57.727 32.293 1.00 17.69 C
ATOM 489 CG LEU A 367 29.740 58.906 31.440 1.00 18.58 C
ATOM 490 CD1 LEU A 367 30.935 59.515 30.724 1.00 17.30 C
ATOM 491 CD2 LEU A 367 28.692 58.434 30.443 1.00 16.88 C
ATOM 492 N ARG A 368 29.568 55.391 34.864 1.00 18.04 N
ATOM 493 CA ARG A 368 30.177 54.231 35.509 1.00 19.28 C
ATOM 494 C ARG A 368 29.911 52.921 34.788 1.00 19.39 C
ATOM 495 O ARG A 368 30.795 52.068 34.686 1.00 20.04 O
ATOM 496 CB ARG A 368 29.716 54.139 36.959 1.00 17.34 C
ATOM 497 CG ARG A 368 30.452 55.110 37.862 1.00 16.27 C
ATOM 498 CD ARG A 368 29.880 55.110 39.266 1.00 20.42 C
ATOM 499 NE ARG A 368 28.437 55.319 39.261 1.00 18.88 N
ATOM 500 CZ ARG A 368 27.592 54.698 40.074 1.00 16.32 C
ATOM 501 NH1 ARG A 368 28.049 53.826 40.962 1.00 18.04 N
ATOM 502 NH2 ARG A 368 26.294 54.948 39.996 1.00 15.98 N
ATOM 503 N ASN A 369 28.701 52.768 34.267 1.00 20.09 N
ATOM 504 CA ASN A 369 28.342 51.546 33.558 1.00 21.99 C
ATOM 505 C ASN A 369 27.994 51.792 32.095 1.00 21.05 C
ATOM 506 O ASN A 369 27.173 51.090 31.510 1.00 23.68 O
ATOM 507 CB ASN A 369 27.178 50.870 34.276 1.00 24.40 C
ATOM 508 CG ASN A 369 27.498 50.581 35.726 1.00 26.56 C
ATOM 509 OD1 ASN A 369 27.953 49.485 36.065 1.00 31.85 O
ATOM 510 ND2 ASN A 369 27.277 51.568 36.592 1.00 23.39 N
ATOM 511 N ALA A 370 28.633 52.794 31.507 1.00 20.28 N
ATOM 512 CA ALA A 370 28.394 53.135 30.113 1.00 18.65 C
ATOM 513 C ALA A 370 29.131 52.171 29.190 1.00 17.03 C
ATOM 514 O ALA A 370 30.094 51.534 29.598 1.00 16.36 O
ATOM 515 CB ALA A 370 28.864 54.553 29.852 1.00 14.10 C
ATOM 516 N SER A 371 28.663 52.050 27.951 1.00 16.37 N
ATOM 517 CA SER A 371 29.336 51.204 26.977 1.00 15.12 C
ATOM 518 C SER A 371 30.365 52.139 26.347 1.00 15.55 C
ATOM 519 O SER A 371 30.282 53.357 26.512 1.00 16.15 O
ATOM 520 CB SER A 371 28.359 50.703 25.917 1.00 16.99 C
ATOM 521 OG SER A 371 27.573 51.767 25.420 1.00 22.49 O
ATOM 522 N HIS A 372 31.331 51.587 25.628 1.00 16.60 N
ATOM 523 CA HIS A 372 32.359 52.420 25.025 1.00 16.83 C
ATOM 524 C HIS A 372 31.848 53.546 24.135 1.00 19.05 C
ATOM 525 O HIS A 372 32.117 54.723 24.401 1.00 17.13 O
ATOM 526 CB HIS A 372 33.343 51.570 24.220 1.00 18.31 C
ATOM 527 CG HIS A 372 34.565 52.327 23.804 1.00 16.27 C
ATOM 528 ND1 HIS A 372 35.725 52.347 24.552 1.00 15.35 N
ATOM 529 CD2 HIS A 372 34.806 53.116 22.725 1.00 16.64 C
ATOM 530 CE1 HIS A 372 36.615 53.116 23.962 1.00 17.77 C
ATOM 531 NE2 HIS A 372 36.086 53.596 22.849 1.00 16.13 N
ATOM 532 N GLU A 373 31.117 53.198 23.079 1.00 17.98 N
ATOM 533 CA GLU A 373 30.622 54.215 22.159 1.00 21.43 C
ATOM 534 C GLU A 373 29.713 55.247 22.798 1.00 18.53 C
ATOM 535 O GLU A 373 29.877 56.441 22.547 1.00 22.40 O
ATOM 536 CB GLU A 373 29.912 53.581 20.957 1.00 24.74 C
ATOM 537 CG GLU A 373 30.035 54.421 19.682 1.00 31.92 C
ATOM 538 CD GLU A 373 28.982 54.095 18.626 1.00 37.31 C
ATOM 539 OE1 GLU A 373 28.454 52.959 18.638 1.00 43.29 O
ATOM 540 OE2 GLU A 373 28.684 54.976 17.780 1.00 34.25 O
ATOM 541 N GLN A 374 28.760 54.806 23.618 1.00 16.93 N
ATOM 542 CA GLN A 374 27.838 55.741 24.278 1.00 16.67 C
ATOM 543 C GLN A 374 28.632 56.732 25.145 1.00 14.57 C
ATOM 544 O GLN A 374 28.309 57.915 25.189 1.00 15.06 O
ATOM 545 CB GLN A 374 26.815 54.991 25.154 1.00 18.40 C
ATOM 546 CG GLN A 374 25.390 54.787 24.596 1.00 15.08 C
ATOM 547 CD GLN A 374 25.045 55.619 23.368 1.00 19.83 C
ATOM 548 OE1 GLN A 374 24.640 56.781 23.478 1.00 19.49 O
ATOM 549 NE2 GLN A 374 25.180 55.017 22.193 1.00 19.93 N
ATOM 550 N ALA A 375 29.660 56.244 25.839 1.00 14.19 N
ATOM 551 CA ALA A 375 30.503 57.106 26.674 1.00 14.92 C
ATOM 552 C ALA A 375 31.199 58.139 25.794 1.00 12.85 C
ATOM 553 O ALA A 375 31.282 59.318 26.142 1.00 14.07 O
ATOM 554 CB ALA A 375 31.550 56.277 27.413 1.00 13.41 C
ATOM 555 N ALA A 376 31.710 57.678 24.654 1.00 17.76 N
ATOM 556 CA ALA A 376 32.385 58.557 23.710 1.00 16.53 C