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tau value for GCaMP8 #183

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immj22 opened this issue Oct 7, 2021 · 2 comments
Open

tau value for GCaMP8 #183

immj22 opened this issue Oct 7, 2021 · 2 comments

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@immj22
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immj22 commented Oct 7, 2021

Hi,

now my lab is using GCaMP8 version instead of GCaMP6 for two-photon imaging. Since the decay time of GCaMP8 is faster than GCaMP6 and also if my understanding is correct, the Suite2p is developed based on GCaMP6 data, so we think that we need to change tau value. I'm wondering whether you have any recommendation value for GCaMP8.

@hmacomber
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I'd also love to get a clear answer on this as we're on 8f now as well. Anecdotally it seems to do an okay job with the tau set to 0.1, but that was determined entirely by trial-and-error guessing and not something empiric.

@iampritishpatil
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0.1 also works well for me, though it can be as low as 0.07, like in the paper.

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