openssl issue with Rstudio when installing monocle3 through bioconda

[iaradsouza1]

Hello,

I'm using Rstudio through conda environments. Therefore, the recommended way of installing R packages is through conda channels. I've installed monocle3 using the bioconda channel in a newly created environment. However, when opening Rstudio, it raises this error:

Error in tools::startDynamicHelp() : 
  internet routines cannot be loaded

I've observed this error in 2023.12.0 and 2022.07.0 versions of Rstudio. When comparing the versions of openssl in another conda environment that does not present this error, I noted that openssl version is 3.1.3. The version of openssl attached to monocle3 in bioconda is the 3.2.0 (the newest).

Then, I just downgraded the openssl version which comes with monocle3 (3.2.0) to the 3.1.3 and the error disappears.

Maybe it would be beneficial to check the monocle3 requirements regarding the openssl package.