Leveraging the recent release of the anatomical fiducial framework for developing an open software infrastructure to solve the landmark regression problem on 3D MRI images
1 - skull stripping 2 - conforming image 3 - intensity normalization (i.e., WM to 110)
1 - extract points from landmark file (.fcsv is supported) 2 - extact a landmark Euclidean distance map (could be considered probability map; each voxel communicates the distance to a AFID of interest)
1 - a standard 3D Unet