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What did you expect to happen?
A PEtab parameter with estimate=0 is treated as a fixed parameter during import.
The parameter is defined in the PEtab parameters table, then the initial condition species(t=0) = parameter is specified in the PEtab conditions table. The parameter does not exist in the SBML model.
What has happened instead?
The parameter is treated as estimated.
I also see the warning
- amici.petab_import - WARNING - Column 'initial_Susceptible' used in condition table but not entity with the corresponding ID exists. Ignoring.
To Reproduce
Compile the attached PEtab problem twice, with initial_Susceptible set to estimate=0 the first time, and estimate=1 the second time. The generated C++ are identical (the parameter isn't fixed in the first case).
What did you expect to happen?
A PEtab parameter with
estimate=0
is treated as a fixed parameter during import.The parameter is defined in the PEtab parameters table, then the initial condition
species(t=0) = parameter
is specified in the PEtab conditions table. The parameter does not exist in the SBML model.What has happened instead?
The parameter is treated as estimated.
I also see the warning
To Reproduce
Compile the attached PEtab problem twice, with
initial_Susceptible
set toestimate=0
the first time, andestimate=1
the second time. The generated C++ are identical (the parameter isn't fixed in the first case).AMICI version and system environment
Bertozzi_PNAS2020.zip
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